Results 31 to 40 of about 164,060 (248)
PLoS ONE, 2014 E-cadherin is a key cell-cell adhesion molecule but the impact of receptor density and the precise contribution of individual cadherin ectodomains in promoting cell adhesion are only incompletely understood.
Dagmar Fichtner +8 more
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E-cadherin is transcriptionally activated via suppression of ZEB1 transcriptional repressor by small RNA-mediated gene silencing. [PDF]
PLoS ONE, 2011 RNA activation has been reported to be induced by small interfering RNAs (siRNAs) that act on the promoters of several genes containing E-cadherin. In this study, we present an alternative mechanism of E-cadherin activation in human PC-3 cells by siRNAs ...
Minami Mazda +3 more
doaj +1 more source
E-cadherin, guardian of liver physiology [PDF]
Clinics and Research in Hepatology and Gastroenterology, 2015 E-cadherin is a cell-to-cell adhesion molecule involved in epithelial cell behavior, tissue formation and cancer suppression. In the liver, E-cadherin is expressed by hepatocytes and biliary epithelial cells. However, the exact role of E-cadherin in hepatic pathophysiology remains largely unknown.
Gonzalez-Sanchez, Ester +3 more
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Clinics, 2011 OBJECTIVE: To evaluate the expression of the cell adhesion molecules E-cadherin and N-cadherin and the transcription factor Snail in invasive ductal breast carcinomas and to determine their relationships with clinicopathological features.
Hanan Mohamed Abd ElMoneim +1 more
doaj +1 more source
Microtubules Inhibit E-Cadherin Adhesive Activity by Maintaining Phosphorylated p120-Catenin in a Colon Carcinoma Cell Model. [PDF]
PLoS ONE, 2016 Tight regulation of cadherin-mediated intercellular adhesions is critical to both tissue morphogenesis during development and tissue homeostasis in adults.
Stephanie L Maiden +2 more
doaj +1 more source
E-cadherin expression in thymomas
Yonsei Medical Journal, 1998 For the purpose of investigating the pattern of E-cadherin (E-CD) expression in thymomas, 72 cases were immunostained using monoclonal antibody (HECD-1) and microwave-enhanced immunohistochemical method on formalin-fixed, paraffin-embedded tissue sections. The thymomas were classified according to modified Müller-Hermelink classification.
W I, Yang +3 more
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E-Cadherin Engagement Stimulates Tyrosine Phosphorylation [PDF]
Cell Adhesion and Communication, 1997 Cadherins are cell adhesion molecules concentrated at intercellular adherens junctions, where they form a multiprotein complex with cytoplasmic catenins. Although cell-cell interactions affect many aspects of cell behavior, little is known about signaling pathways triggered by cadherin engagement.
M S, Kinch +3 more
openaire +2 more sources
Characterizing interactions in E-cadherin assemblages
Biophysical Journal, 2023 Cadherin intermolecular interactions are critical for cell-cell adhesion and play essential roles in tissue formation and the maintenance of tissue structures. In this study, we focus on E-cadherin, a classical cadherin that connects epithelial cells, to understand how they interact in cis and trans conformations when attached to the same cell or ...
Sayane Shome +3 more
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Transcriptional repression of E-cadherin by human papillomavirus type 16 E6. [PDF]
PLoS ONE, 2012 There is increasing evidence supporting DNA virus regulation of the cell adhesion and tumour suppressor protein, E-cadherin. We previously reported that loss of E-cadherin in human papillomavirus (HPV) type 16-infected epidermis is contributed to by the ...
Zarina J D'Costa +5 more
doaj +1 more source
Cancer: leaping the E‐cadherin hurdle [PDF]
The EMBO Journal, 2015 Aberrant activation of the Wnt signaling pathway is a common cause of colon cancer and other tumor types, accomplishing many of the hallmarks of cancer including sustained proliferative signaling, replicative immortality, reprogrammed metabolism, angiogenesis, and invasion.
Chen, GT, Waterman, ML
openaire +4 more sources