Results 71 to 80 of about 164,060 (248)
FEBS Open Bio, EarlyView.Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
The Journal of Cell Biology, 2004 ![Graphic][1] E-cadherin endocytosis is blocked by IQGAP1 unless actin filaments are disrupted by Lat-A.E-cadherin interacts with other E-cadherin molecules on neighboring cells to form cell–cell adhesions.
openaire +2 more sources
PLoS ONE, 2011 The Cas scaffolding proteins (NEDD9/HEF1/CAS-L, BCAR1/p130Cas, EFSSIN, and HEPL/CASS4) regulate cell migration, division and survival, and are often deregulated in cancer. High BCAR1 expression is linked to poor prognosis in breast cancer patients, while upregulation of NEDD9 contributes to the metastatic behavior of melanoma and glioblastoma cells ...
Nadezhda Tikhmyanova, Erica A Golemis
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Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce +72 more
wiley +1 more source
JCI Insight, 2023 Metastatic progression of epithelial cancers can be associated with epithelial-mesenchymal transition (EMT) including transcriptional inhibition of E-cadherin (CDH1) expression.
Kuppusamy Balamurugan +12 more
doaj +1 more source
Advanced Functional Materials, EarlyView.A mechanically tunable hydrogel composed of gelatin, chondroitin sulfate and laminin promotes angiogenesis in vitro without the supplement of growth factors. Endothelial cells morphogenesis was further enhanced by medium conditioned with bioactive glass 58S‐released ions (Ca and Si), thus offering a promising strategy to vascularize 3D tissue ...
Marco Piazzoni +13 more
wiley +1 more source
E-cadherin: gatekeeper of airway mucosa and allergic sensitization
Trends in Immunology, 2011 The airway epithelium plays a role in immune regulation during environmental challenge, which is intertwined with its barrier function and capacity to limit submucosal access of environmental factors. In asthma, mucosal barrier function is often compromised, with disrupted expression of the adhesion molecule E-cadherin.
Nawijn, Martijn C +4 more
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Advanced Functional Materials, EarlyView.Fibrous benzenetrispeptide (BTP) hydrogels, fabricated via strain‐promoted azide‐alkyne cycloaddition (SPAAC) crosslinking, form robust, bioinert networks. These hydrogels can support 3D cell culture, where cell viability and colony growth depend on the fiber content.
Ceren C. Pihlamagi +5 more
wiley +1 more source
Expression of E-cadherin and specific CXCR3 isoforms impact each other in prostate cancer
Cell Communication and Signaling, 2019 Background Carcinoma cells shift between epithelial and mesenchymal phenotypes during cancer progression, as defined by surface presentation of the cell-cell cohesion molecule E-cadherin, affecting dissemination, progression and therapy responsiveness ...
Bo Ma +4 more
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Data in Brief, 2018 This article contains data related to the research article entitled, “A catenin-dependent balance between N-cadherin and E-cadherin controls neuroectodermal cell fate choices” (Rogers et. al., 2018) [1].
Crystal D. Rogers
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