Results 71 to 80 of about 811,917 (322)
Challenges for E-Government Strategy [PDF]
Governments worldwide are faced with the challenge of transformation and the need to reinvent government systems in order to deliver efficient and cost effective services, information and knowledge through information and communication technologies ...
Mircea GEORGESCU
core
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Introducing the municipal digital offering index for evaluating online services and addressing the digital divide [PDF]
PeerJ Computer ScienceThis research introduces the Municipal Digital Offering Index (MDOI) to assess municipal online service development in Chile. The study utilizes content analysis of municipal websites, creating a systematic instrument to evaluate digital services.
Carolina Busco +5 more
doaj +2 more sources
Development of System Architecture for E-Government Cloud Platforms
, 2016 Requirements and criteria for selection of cloud platform and platform visualization are stated by which optimal cloud products will be chosen for the Republic of Kazakhstan e-Government considering quality-price ratio, and also the framework of ...
Aubakirov, M., Nikulchev, E.
core +2 more sources
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
SEARCHING AND TRACKING OF LOCATION BY PROXY BASED APPROACH
ICTACT Journal on Soft Computing, 2017 Location based services became an important application in recent world. Users can search a location using smart phones and can also track the location. It is also possible for the users to retrieve information about the nearest location.
K. Nirmala +1 more
doaj
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
E-government em portais públicos de municípios
, 2021 Fabrício Ramos Neves +1 more
openalex +2 more sources
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source