Results 41 to 50 of about 22,560,687 (314)
Infrastructure priority list [PDF]
The Infrastructure Priority List is a prioritised list of nationally significant investments. It provides decision makers with advice and guidance on specific infrastructure investments that will underpin Australia\u27s continued prosperity ...
Infrastructure Australia
core
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Preliminary e-infrastructure for digital metrology
The digital transformation of the economy is the result of profound changes in science, technology and society. The response to these changes should be the latest version of the SI and the corresponding development of the new measurement standards.
Pavel Neyezhmakov +2 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Machine Learning Assessment of Crash Severity in ADS and ADAS-L2 Involved Crashes with NHTSA Data
As the deployment of Automated Driving Systems (ADS) and Advanced Driver Assistance Systems (ADAS-L2) expands, understanding their real-world safety performance becomes essential.
Nasim Samadi +5 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
One of the best ways to achieve global literacy is through communication, collaborative learning, research, and problem solving. Technology helps tremendously in these areas, so it is a great tool to use in this process.
Chiome, Chrispen
core +1 more source
Introduction Colorectal cancer (CRC) represents one of the most important public health issues worldwide and the third most diagnosed cancer globally.
Carlotta Bertolina +6 more
doaj +1 more source

