Results 41 to 50 of about 22,560,687 (314)

Infrastructure priority list [PDF]

open access: yes, 2016
The Infrastructure Priority List is a prioritised list of nationally significant investments. It provides decision makers with advice and guidance on specific infrastructure investments that will underpin Australia\u27s continued prosperity ...
Infrastructure Australia
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Preliminary e-infrastructure for digital metrology

open access: yesMeasurement: Sensors, 2022
The digital transformation of the economy is the result of profound changes in science, technology and society. The response to these changes should be the latest version of the SI and the corresponding development of the new measurement standards.
Pavel Neyezhmakov   +2 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Machine Learning Assessment of Crash Severity in ADS and ADAS-L2 Involved Crashes with NHTSA Data

open access: yesSafety
As the deployment of Automated Driving Systems (ADS) and Advanced Driver Assistance Systems (ADAS-L2) expands, understanding their real-world safety performance becomes essential.
Nasim Samadi   +5 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

e-Infrastructure Acceptance in e-Health, eLearning and e-Agriculture in Zimbabwe: The Quest for the User Acceptance Variable

open access: yes, 2013
One of the best ways to achieve global literacy is through communication, collaborative learning, research, and problem solving. Technology helps tremendously in these areas, so it is a great tool to use in this process.
Chiome, Chrispen
core   +1 more source

MMR-Colon Study: First Attempt at Quantifying MMR Protein Expression as a Prognostic Factor in Colorectal Cancer

open access: yesEpidemiology, Biostatistics and Public Health
Introduction Colorectal cancer (CRC) represents one of the most important public health issues worldwide and the third most diagnosed cancer globally.
Carlotta Bertolina   +6 more
doaj   +1 more source

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