Results 61 to 70 of about 22,560,687 (314)
Integration of the Laboratory Instruments with e-Infrastructure
Computational Methods in Science and Technology, 2010 A combination of networks, computational, storage infrastructure and the scientific instrumentation (equipped with sensor networks) composes a new kind of e-Infrastructure. The integration of scientific instruments into e-Infrastructure empowers possibilities in conducting experiments. The development of technologies that allow remote and shared access
M. PLÓCIENNIK +10 more
openaire +2 more sources
Report on e-infrastructure evaluation
, 2021 This document reports the results of an e-infrastructure evaluation performed by the Improved Observation Usage in NWP (iOBS) project. The goal was to evaluate how future e-infrastructure for numerical weather prediction (NWP) could make use of cloud and high-performance computing (HPC) resources.
Kallio, Aleksi +2 more
openaire +2 more sources
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
10 year infrastructure plan : 2019-2028
, 2020 The Northern Territory provides many opportunities for strategic private sector investment and the Northern Territory Government will support the growth and adaptability of local industry so it is strategically aligned with our growth sectors and global ...
core
Victoria's draft 30-year infrastructure strategy
, 2016 Infrastructure Victoria is undertaking the first ever thirty year infrastructure strategy for Victoria. The community and stakeholders are active participants in the development of this strategy through consultation and engagement.
Infrastructure Victoria
core +1 more source
IATSS Research, 2017 For the first time, a driving simulator has been integrated with a traffic simulator at the network level to allow subjects to drive in a fairly realistic environment with a realistic traffic flow and density. A 10 mi2 (25 km2) network was developed in a
Mansoureh Jeihani +2 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
ChemosensorsAsbestos research, identification, and quantification have been performed over the years, and the relationship between fiber inhalation and lung disease development is well defined.
Alessandro Croce +8 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source