Results 131 to 140 of about 3,162,158 (317)

Challenges and learning outcomes of educational design research for PhD students

, 2016
Educational design research (EDR) is described as a complex research approach. The challenges resulting from this complexity are typically described as procedural, whereas EDR might also be challenging for different reasons, specifically for early career
Leerstoel van Tartwijk, Renske A.M. de Kleijn, Leerstoel van Gog, Bronkhorst, Larike H., Education and Learning: Development in Interaction, Larike H. Bronkhorst, Bronkhorst, L.H., de Kleijn, R.A.M., Hafd Onderwijsadvies en training, de Kleijn, Renske A.M.   +9 more
core   +1 more source

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem, Angel Liu, Sargis Manukyan, Mustafa Subhi, Elaina Luskin, Bryan Quah, Sreekanth Madhusoodhanan Nair, Arzu C. Has Silemek, Gabriela Zabala, Yujie Cui, Laura Locke, Paula Barreras, Marwa Kaisey, Vinicius Calsavara, Daniel S. Reich, Nancy L. Sicotte, Pascal Sati, Omar Al‐Louzi   +17 more
wiley   +1 more source

Development of a Social Gamified Platform for e-Learning

, 2017
The way in which nowadays education is evolving, makes it possible to associate it with MOOCs courses and gamification techniques to improve learning outcomes of students. It is indeed a new combination, but with a high potential. To this end, this paper shows the development of an educational e-learning platform built upon the Elgg open-source social ...
Caro-Alvaro, Sergio, Garcia-Lopez, Eva, Garcia-Cabot, Antonio, de Marcos, Luis, Martínez-Herráiz, José Javier   +4 more
openaire   +2 more sources

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Integrating Learning Development into the Student Experience

, 2013
‘Embedding skills’ has become an educational buzz word which evokes many different responses. Whilst acknowledging this diversity, this article focuses on the promotion of the integration of skills development into the subject curriculum as theory is put
Hill, Patricia, Hill, Pat, Tinker, Amanda   +2 more
core  

Investigation of the Status of IoT-Based Health Information Systems in a Three-Dimensional Conceptual Framework

مجله انفورماتیک سلامت و زیست پزشکی, 2020
Introduction: The ability to transfer data over the Internet of Things (IoT) to make right and timely decisions through accurate data collection has provided incredible interactive power and has resulted in an intelligent world with automated decision ...
Shirin Ayani, Khadijeh Moulaei, Mohammad Javad Mahabadi   +2 more
doaj  

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

A new ethos for a multipolar design learning community: A mechanism for the development and diffusion of teaching materials on design for sustainability in an open-source and copy left ethos

, 2010
Copyright @ 2010 International Association of Technology, Education and DevelopmentFinally, the time has arrived in which there is a shared opinion that sustainable development requires a system discontinuity, meaning that radical changes in the way we ...
CESCHIN, FABRIZIO, VEZZOLI, CARLO ARNALDO, Vezzoli, C, Ceschin, F   +3 more
core