Results 121 to 130 of about 4,764,911 (309)

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Investigation of the Status of IoT-Based Health Information Systems in a Three-Dimensional Conceptual Framework

مجله انفورماتیک سلامت و زیست پزشکی, 2020
Introduction: The ability to transfer data over the Internet of Things (IoT) to make right and timely decisions through accurate data collection has provided incredible interactive power and has resulted in an intelligent world with automated decision ...
Shirin Ayani, Khadijeh Moulaei, Mohammad Javad Mahabadi   +2 more
doaj  

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source

Impact of e-learning on learner participation, attainment, retention, and progression in further education : report of a scoping study [PDF]

, 2004
Recent and ongoing work has assessed progress in the provision of Information and Learning Technologies (ILT) to support e-learning in the UK further education (FE) sector.
Hall, John, Harris, Rachel, McAteer, Erica, Muirhead, Alison, Schmoller, Seb, Thorpe, Graham   +5 more
core  

Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan, Marco Pitteri, Michael Foster, Sara Collorone, Sara Salama, Elisa Colato, Ferran Prados, Baris Kanber, Marios Yiannakas, Claudia A. M. Gandini Wheeler‐Kingshott, Indran Davagnanam, Frederik Barkhof, Declan Chard, Olga Ciccarelli, Ahmed Toosy   +14 more
wiley   +1 more source

Student Partnership in E-learning: the Development of Online Resources for Students by Students in Dentistry [PDF]

, 2016
Dentistry is a dynamic and ever changing specialty that has been strongly influenced by developments in technology and therefore our teaching strategies must evolve to keep pace with these changes.
Al-Ani, Ziad, Bragg, Jeremy, Hudda, Shabana, McAllan, Wendy, McKerlie, Robert, Rennie, Evelyn, Ritchie, Martyn, Taha, Amr, Wasige, Claudia   +8 more
core  

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source

E-Learning Methodology Development Using Modeling

, 2011
Simulation and modeling computer programs are concerned with construction of models for analyzing different perspectives and possibilities in changing conditions environment. The paper presents theoretical justification and evaluation of qualitative e-learning development model in perspective of advancing modern technologies.
Cakula, Sarma, Sedleniece, Maija
openaire   +1 more source

Evaluating empowerment and control of HE e-learning in a secure environment

, 2008
With the increased spread of HE distance learning into a wide variety of contexts it is important for us to understand the factors involved in its successful deployment for students.
Adams, Anne, Pike, Anne
core  

E-Pedagogy of Handheld Devices 2013 Survey: Patterns of student use for learning [PDF]

, 2015
The Pedagogy of Ebooks (E-Ped) project began in 2012 and seeks to document, analyse and explain the changing study practices of UK distance learning students as they employ, adapt and integrate the use of new portable digital devices such as e-book ...
Cross, Simon, Healing, Graham, Sharples, Mike   +2 more
core