Results 231 to 240 of about 211,577 (291)

Mechanistic insights into the iron-sulfur cluster-dependent interaction of the autophagy receptor NCOA4 with the E3 ligase HERC2. [PDF]

Proc Natl Acad Sci U S A
Liu H, Shen L, Gong X, Zhou X, Huang Y, Zhou Y, Guo Z, Guo H, Wang S, Pan L.   +9 more
europepmc   +1 more source

E3 Ubiquitin-Protein Ligase RFWD3 [PDF]

, 2020
openaire   +1 more source

Gut microbiome‐derived metabolites show promise in cancer research and therapy

Interdisciplinary Medicine, EarlyView.
The metabolites produced by the gut microbiome, which are subject to regulation by multiple factors, play a pivotal role in the progression of various types of cancer. These metabolites not only function as potential biomarkers for the early detection and monitoring of tumor development, but also actively participate in cancer therapeutic processes ...
Kangjie Yang, Yifan Wang, Daolin Tang, Peilong Li, Lutao Du   +4 more
wiley   +1 more source

TaGW2-TaVOZ1 module regulates wheat salt tolerance via both E3 ligase-dependent and -independent pathways. [PDF]

Sci Adv
Li S, Zhang P, Wang X, Feng W, Zhu H, Qin Z, Chen B, Wang C, Nie X, Kang Z, Mao H.   +10 more
europepmc   +1 more source

Exploring the Relationship Between MDM4 Gene Polymorphisms (rs1380576 and rs4245739) and Breast Cancer Susceptibility in Bangladesh: A Case–Control Study

Journal of Clinical Laboratory Analysis, EarlyView.
Our findings indicated that the rs4245739 A>C polymorphism was not associated with BC risk in the Bangladeshi population, whereas the rs1380576 C>G polymorphism was significantly associated with BC risk. This study provides new insights into the genetic factors influencing breast cancer susceptibility in the Bangladeshi population, highlighting the ...
J. M. Aousiful Islam, Sharif Ahamed, Shafiqul Islam, M. Mahboob Hossain, Md Sadbean Hossain, Md. Shaki Mostaid, Md. Rabiul Islam, Md. Aminul Haque   +7 more
wiley   +1 more source

Mechanism of D-type cyclin recognition by the AMBRA1 E3 ligase receptor. [PDF]

Sci Adv
Wang Y, Liu M, Wang S, Mai X, Wang X, Teng F, Lyu T, Su MY, Stjepanovic G.   +8 more
europepmc   +1 more source

Enhancing polyphenol synthesis and antioxidant activity in Camellia sinensis using shikimic and salicylic acids

JSFA reports, EarlyView.
Abstract Background Camellia sinensis, widely consumed as tea, is the second most popular beverage globally and is valued for its health benefits. However, environmental stressors pose a significant challenge to the tea industry. This study investigates the potential of shikimic acid (ShA) and its derivative, salicylic acid (SA), as inducers to enhance
Mir Sultanul Arafin, Shelina Akter Sheuli, Sadia Sultana, Mahir Azmal, Ajit Ghosh   +4 more
wiley   +1 more source

PARG inhibition suppresses breast cancer progression and potentiates immunoresponse through MTDH degradation mediated by E3 ligase ITCH-dependent ubiquitination. [PDF]

NPJ Breast Cancer
Wang J, Dong Y, Lun W, Nai M, Shi Y, Geng J, Cai W, Liu J, Li H, Li L.   +9 more
europepmc   +1 more source

UBE3A Inhibits Trophoblast Cell Migration and Invasion by Promoting ITGB1 Degradation and Affecting PI3K/AKT Signaling

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Preeclampsia (PE) is an obstetric disease that is characterized by reduced migration and invasion of placental trophoblast cells. Here, the effects of the E3 ubiquitin ligase UBE3A on the migration and invasion of trophoblast cells were evaluated.
Xiu‐Jun Li, Ning Wang, Fan Jiang, Jie‐Cheng Yang, Yan‐Yun Wang, Kun Wang   +5 more
wiley   +1 more source

Ring Finger Protein 1, a Novel Ubiquitin E3 Ligase Targeting Cancerous Inhibitor of Protein Phosphatase 2A to Suppress Smoking-Induced Lung Tumorigenesis. [PDF]

MedComm (2020)
Jeong IH, Yun JK, Jin JO, Lee GD, Lee PC.   +4 more
europepmc   +1 more source