Results 231 to 240 of about 68,518 (300)

High-Throughput Discovery of Substrate Peptide Sequences for E3 Ubiquitin Ligases Using a cDNA Display Method. [PDF]

Chembiochem
Tamagawa K, Campbell RE, Terai T.
europepmc   +1 more source

E3 Ubiquitin-Protein Ligase UHRF1 [PDF]

, 2020
openaire   +1 more source

Testis‐Enriched F‐Box Protein FBXO39 Is Important for Spermiogenesis and Male Fertility in Mice

Andrology, EarlyView.
ABSTRACT Background The SCF (Skp–Cullin–F‐box) complex is a major class of E3 ubiquitin ligases. F‐box proteins constitute the SCF complex and play a critical role in recognizing substrates for ubiquitination. In mice, several F‐box proteins, including FBXO36 and FBXO39, are predominantly expressed in testes.
Yuki Kaneda, Haruhiko Miyata, Masahito Ikawa   +2 more
wiley   +1 more source

Human E3 ubiquitin ligases: accelerators and brakes for SARS-CoV-2 infection. [PDF]

Biochem Soc Trans
Pellman J, Goldstein A, Słabicki M.
europepmc   +1 more source

E3 Ubiquitin-Protein Ligase TRIM36 [PDF]

, 2020
openaire   +1 more source

Red blood cell membrane proteome as a reporter of disease severity, transfusion impact and genetic background in transfusion‐dependent β‐thalassaemia

British Journal of Haematology, EarlyView.
Summary Omics technologies have transformed research in haemoglobinopathies, yet the proteome of RBCs remains largely unexplored in transfusion‐dependent thalassaemia (TDT). In this proteomic analysis, Red blood cell (RBC) membranes from 48 adults with TDT were compared with healthy controls.
Konstantina Theocharaki, Sophia Delicou, Aikaterini Ntzoura‐Kani, Nikolaos Simantiris, Marianna Politou, Veroniki Komninaka, Martina Samiotaki, Jerome Zoidakis, Marianna H. Antonelou   +8 more
wiley   +1 more source

Non‐canonical PKG1 regulation in cardiovascular health and disease

British Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

Structural basis for C-degron selectivity across KLHDCX family E3 ubiquitin ligases. [PDF]

Nat Commun
Scott DC, Chittori S, Purser N, King MT, Maiwald SA, Churion K, Nourse A, Lee C, Paulo JA, Miller DJ, Elledge SJ, Harper JW, Kleiger G, Schulman BA.   +13 more
europepmc   +1 more source

Evolution of cullin E3 ubiquitin ligases and function in trypanosomes

, 2023
del Pino RC, Zoltner M, Yamada K, Butterfield ER, Field MC.   +4 more
europepmc   +1 more source

E3 Ubiquitin-Protein Ligase COP1 [PDF]

, 2020
openaire   +1 more source