The R2TP complex stabilises E7 to drive human papillomavirus-mediated pathogenesis in cellular models of cervical cancer. [PDF]
Shadang M +9 more
europepmc +1 more source
Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu +6 more
wiley +1 more source
Head and neck cancer therapeutic vaccines: a review. [PDF]
Huetteman A, Rabinowits G.
europepmc +1 more source
Interactive Groupwise Comparison for Reinforcement Learning from Human Feedback
The standard RLHF uses pairwise comparisons and therefore requires a large number of comparisons leading to a high workload. The comparison pairs are suggested by the system and cannot be chosen by the user. Our RLHF approach provides more agency to the user and demands less work: we leverage the user's visual abilities to effectively explore the ...
Jan Kompatscher +4 more
wiley +1 more source
Blood plasma and oral rinse liquid profiling for human papillomavirus in head and neck cancer - Unmasking false-positive p16 tissue cases and tracking disease dynamics. [PDF]
Mack M +17 more
europepmc +1 more source
Abstract Annotation is a central mechanism in visualization design that enables people to communicate key insights. Prior research has provided essential accounts of the visual forms annotations take, but less attention has been paid to the decisions behind them.
Md Dilshadur Rahman +3 more
wiley +1 more source
The Role of HPV and Hormone in Cervical Precancer and Cancer: Molecular Pathophysiology and Cell Biology of Disease and Treatment. [PDF]
Kao PY, Chen JH, Chen KH.
europepmc +1 more source
REINA study shows decreased immediate and long‐term risks of CIN2+ and CIN3+ lesions in mRNA HPV‐positive women with minor cytological abnormalities after a previous negative Aptima HPV test in the first round. The decreased CIN2+/CIN3+ risks, below colposcopy referral thresholds, can modify women's management, highlighting the importance of ...
Rosario Granados +6 more
wiley +1 more source
Silencing SFRP1 in bone mesenchymal stem cells alleviates pediatric B-ALL-driven bone loss by activating Wnt/β-catenin signaling. [PDF]
Li M +10 more
europepmc +1 more source
HPV42 – a human papillomavirus classified as a low‐risk type with oncogenic potential
Summary Human papillomavirus (HPV) type 42 is a rare HPV type currently classified as “low‐risk” and belongs to the alpha genus. It has primarily been detected in benign vulvar papillomas and is predominantly associated with benign lesions such as anogenital warts.
Sven Niklas Burmann +7 more
wiley +1 more source

