Results 161 to 170 of about 86,081 (238)

A Spike-Linked HPV16 E7 DNA Vaccine Induces Potent Antitumor and Anti-Spike Immune Responses. [PDF]

Int J Mol Sci
Xu Y, Liu Y, Chang YC, Tsai YC, Huang CH, Wu TC, Hung CF.   +6 more
europepmc   +1 more source

Progress in bone tissue engineering biomaterials: Development, challenges, and prospects

VIEW, EarlyView.
Scheme 1 Application of biomaterials in immunomodulation during bone tissue engineering. Abstract Bone defect repair remains a major clinical challenge in orthopedics. Over 2 million cases caused by trauma, tumors, and other factors occur annually, with large‐scale defects posing a particular bottleneck due to limited self‐healing capacity.
Yuanbin Zhang, Junlei Chai, Quanwei Ding, Luping Liu, Kejie Zhang, Jie Lin, Jianhua Zhang, Youju Huang   +7 more
wiley   +1 more source

Endolysosomal routing combined with immune stimulation enhances anti-tumor efficacy of an HPV16 mRNA therapeutic vaccine. [PDF]

Mater Today Bio
Song W, Ying B, Gao P, Zhang Z, Ma X, Ma J, Yang S, Wu Y, Wu D, Wu J, Du T.   +10 more
europepmc   +1 more source

Biomarkers Predictive of Immunotherapy Efficacy in Head and Neck Squamous Cell Carcinoma: Current Insights and Future Perspectives

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT With the approval of immunotherapies by regulatory bodies, head and neck squamous cell carcinoma (HNSCC) treatment has been revolutionized, and anti‐programmed cell death‐1 (anti‐PD‐1) agents are now the standard for platinum‐resistant recurrent/metastatic HNSCC.
Xiao‐Tong Yan, Zhao‐Hong An, Chang‐Ming An   +2 more
wiley   +1 more source

Immunoinformatics-Driven Rational Design of Altered Peptide Ligands and In Vitro Validation of a Multi-Epitope CTL Formulation Targeting HPV16 E6/E7. [PDF]

Vaccines (Basel)
Dong D, Zhang X, Li B.
europepmc   +1 more source

Distinct Immunometabolic Profiles in Finnish and Russian Karelian Adolescents With Contrasting Allergy Risk

Allergy, EarlyView.
We compared Finnish and Russian Karelian adolescents with contrasting allergy burden using integrated proteomic, metabolomic, and transcriptomic profiling. Finnish adolescents showed a broader pro‐inflammatory PBMC secretory profile consistent with a low‐grade inflammatory phenotype.
Nanna Fyhrquist, Matilda Riskumäki, Piia Karisola, Anni Nieminen, Tiina Laatikainen, Hanna Sinkko, Laura Paalanen, Pekka Jousilahti, Erkki Vartiainen, Mika J. Mäkelä, Tari Haahtela, Harri Alenius   +11 more
wiley   +1 more source

Isolation, characterization, and genomic analysis of a novel lytic bacteriophage with potent antibiofilm activity against multidrug-resistant Acinetobacter baumannii. [PDF]

BMC Microbiol
M Amin E, Aziz RK, Murad FE, Elrakaiby MT, Samir R.   +4 more
europepmc   +1 more source

Palaeoenvironmental and climatic changes from the lateglacial of the Saalian to the Late Weichselian in central Poland: a multiproxy study from Józefów

Boreas, EarlyView.
Józefów site is a case study which provides a detailed record of environmental and climate changes and confirms the main traces of the landscape morphogenesis of the Late Pleistocene established in central‐eastern Europe. This study presents a multiproxy reconstruction of palaeoenvironment under variable climatic conditions from the retreat of the ...
Aleksandra Majecka, Jacek Forysiak, Ryszard Borówka, Andreas Börner, Łukasz Bujak, Leszek Marks, Radosław Mieszkowski, Piotr Moska, Daniel Okupny, Małgorzata Pisarska‐Jamroży, Renata Stachowicz‐Rybka, Krzysztof Stachowicz   +11 more
wiley   +1 more source

A Cell-Penetrating Peptide and Signal Sequence Fusion DNA Vaccine Enhances CD8+ T Cell-Mediated Anti-Tumor Immunity Targeting HPV-16 Cervical Cancer Antigens. [PDF]

Obstet Gynecol Res
Chang YC, McSweeney K, Xu Y, Liu Y, Tsai YC, Wu TC, Hung CF.   +6 more
europepmc   +1 more source

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source