Results 21 to 30 of about 77,626 (259)
Precision medicine: a new era for inner ear diseases
Frontiers in PharmacologyThe inner ear is the organ responsible for hearing and balance. Inner ear dysfunction can be the result of infection, trauma, ototoxic drugs, genetic mutation or predisposition. Often, like for Ménière disease, the cause is unknown.
Elisa Tavazzani +8 more
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Genetic Causes of Inner Ear Anomalies: a Review from the Turkish Study Group for Inner Ear Anomalies
Balkan Medical Journal, 2019 Inner ear anomalies diagnosed using a radiological study are detected in almost 30% of cases with congenital or prelingual-onset sensorineural hearing loss.
Emre Ocak, Duygu Duman, Mustafa Tekin
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Extratympanic Observation of Middle and Inner Ear Structures in Rodents Using Optical Coherence Tomography [PDF]
Clinical and Experimental Otorhinolaryngology, 2020 Objectives This study aimed to investigate whether optical coherence tomography (OCT) provides useful information about the microstructures of the middle and inner ear via extratympanic approach and thereby could be utilized as an alternative diagnostic ...
Se-Joon Oh +5 more
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Frontiers in NeuroscienceHearing loss is the most common sensory disorder in human beings. Cochlear sensory cells are the basis of hearing. Cochlear sensory cells suffer from various acute or chronic injuries, such as excessive sound stimulation, ototoxic drugs, and age-related ...
Yu-Chen Liu, Kai Xu
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Frontiers in Cell and Developmental Biology, 2019 Hair cells are specialized mechanosensitive cells responsible for mediating balance and hearing within the inner ear. In mammals, hair cells are limited in number and do not regenerate.
Cristiana Mattei +14 more
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Inner ear‐specific autoantibodies [PDF]
The Laryngoscope, 1993 AbstractThe sera of patients with idiopathic sensorineural hearing loss (SNHL) were examined, using qualitative immunoblotting (Western blotting), for the presence of inner ear (IE)‐specific autoantibodies. The water‐soluble extracts and the sodium dodecyl sulfate‐soluble extracts were prepared as the antigens from bovine IE tissues and several other ...
S, Yamanobe, J P, Harris
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Immune system of the inner ear as a novel therapeutic target for sensorineural hearing loss
Frontiers in Pharmacology, 2014 Sensorineural hearing loss (SNHL) is a common clinical condition resulting from dysfunction in one or more parts in the auditory pathway between the inner ear and auditory cortex.
Takayuki eOkano
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Assessment of drug permeability through an ex vivo porcine round window membrane model
iScience, 2023 Summary: Delivery of pharmaceutical therapeutics to the inner ear to treat and prevent hearing loss is challenging. Systemic delivery is not effective as only a small fraction of the therapeutic agent reaches the inner ear.
Adele Moatti +9 more
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Application of Nanomedicine in Inner Ear Diseases
Frontiers in Bioengineering and Biotechnology, 2022 The treatment of inner ear disorders always remains a challenge for researchers. The presence of various physiological barriers, primarily the blood–labyrinth barrier (BLB), limits the accessibility of the inner ear and hinders the efficacy of various ...
Qianyu Lin +12 more
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Advanced Functional Materials, EarlyView.FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu +5 more
wiley +1 more source