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Audio-vestibular symptoms in systemic autoimmune diseases [PDF]
, 2018 Immune-mediated inner ear disease can be primary, when the autoimmune response is against the inner ear, or secondary. The latter is characterized by the involvement of the ear in the presence of systemic autoimmune conditions. Sensorineural hearing loss
Adelchi, Croce +7 more
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Diagnostics, 2020 The diagnostics of inner ear diseases are primarily functional, but there is a growing interest in inner ear biomarkers. The present scoping review aimed to elucidate gaps in the literature regarding the definition, classification system, and an overview
Nahla A. Gomaa +4 more
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Inner ear barriers to nanomedicine-augmented drug delivery and imaging
Journal of Otology, 2016 There are several challenges to inner ear drug delivery and imaging due to the existence of tight biological barriers to the target structure and the dense bone surrounding it. Advances in imaging and nanomedicine may provide knowledge for overcoming the
Jing Zou, Ilmari Pyykkö, Jari Hyttinen
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Development of a dynamic virtual reality model of the inner ear sensory system as a learning and demonstrating tool [PDF]
, 2009 In order to keep track of the position and motion of our body in space, nature has given us a fascinating and very ingenious organ, the inner ear. Each inner ear includes five biological sensors - three angular and two linear accelerometers - which ...
Gourinat, Yves +2 more
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Biomedicines, 2021 Zebrafish is an excellent model for exploring the development of the inner ear. Its inner ear has similar functions to that of humans, specifically in the maintenance of hearing and balance. Mafba is a component of the Maf transcription factor family. It
Xiang Chen +10 more
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Modulation of Wnt Signaling Enhances Inner Ear Organoid Development in 3D Culture. [PDF]
PLoS ONE, 2016 Stem cell-derived inner ear sensory epithelia are a promising source of tissues for treating patients with hearing loss and dizziness. We recently demonstrated how to generate inner ear sensory epithelia, designated as inner ear organoids, from mouse ...
Rachel E DeJonge +5 more
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Visualization of macrophage subsets in the development of the fetal human inner ear
Frontiers in Immunology, 2022 BackgroundHuman inner ear contains macrophages whose functional role in early development is yet unclear. Recent studies describe inner ear macrophages act as effector cells of the innate immune system and are often activated following acoustic trauma or
Claudia Steinacher +11 more
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Molecular and functional characterization of gap junctions in the avian inner ear. [PDF]
, 2006 To analyze the fundamental role of gap junctions in the vertebrate inner ear, we examined molecular and functional characteristics of gap junctional communication (GJC) in the auditory and vestibular system of the chicken.
Becker, D, Forge, A, Nickel, R
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Current strategies for drug delivery to the inner ear
Acta Pharmaceutica Sinica B, 2013 For many years, drug delivery to the inner ear has been a challenge to physicians in the treatment of inner ear disorders. In the past decade, the field of inner ear drug delivery has emerged with the development of new biomaterials and drug delivery ...
Hongzhuo Liu, Jinsong Hao, Kevin S. Li
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Potential application value of pigment epithelium-derived factor in sensorineural hearing loss
Frontiers in Neuroscience, 2023 The inner ear is a complex and precise auditory perception system responsible for receiving and converting sound signals into neural signals, enabling us to perceive and understand sound.
Zihui Sun +12 more
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