Results 21 to 30 of about 434,910 (305)

Current strategies for drug delivery to the inner ear

open access: yesActa Pharmaceutica Sinica B, 2013
For many years, drug delivery to the inner ear has been a challenge to physicians in the treatment of inner ear disorders. In the past decade, the field of inner ear drug delivery has emerged with the development of new biomaterials and drug delivery ...
Hongzhuo Liu, Jinsong Hao, Kevin S. Li
doaj   +1 more source

Potential application value of pigment epithelium-derived factor in sensorineural hearing loss

open access: yesFrontiers in Neuroscience, 2023
The inner ear is a complex and precise auditory perception system responsible for receiving and converting sound signals into neural signals, enabling us to perceive and understand sound.
Zihui Sun   +12 more
doaj   +1 more source

Molecular and functional characterization of gap junctions in the avian inner ear. [PDF]

open access: yes, 2006
To analyze the fundamental role of gap junctions in the vertebrate inner ear, we examined molecular and functional characteristics of gap junctional communication (GJC) in the auditory and vestibular system of the chicken.
Becker, D, Forge, A, Nickel, R
core   +1 more source

Effects of Glucocorticoids on the Inner Ear [PDF]

open access: yesFrontiers in Surgery, 2021
Hypothesis: Recently, several lines of evidence have suggested that the inner ear is under hormonal control. It is likely that steroids have some influence on the inner ear.Background: Many clinicians have been empirically using steroids for the treatment of diseases associated with endolymphatic hydrops. The theoretical grounds for this are not clear,
Setsuko Takeda   +2 more
openaire   +4 more sources

Inner ear morphology in the Atlantic molly Poecilia mexicana [PDF]

open access: yes, 2011
Fishes show an amazing diversity in hearing abilities, inner ear structures, and otolith morphology. Inner ear morphology, however, has not yet been investigated in detail in any member of the diverse order Cyprinodontiformes.
Hess, Martin   +2 more
core   +1 more source

Biocompatibility of Liposome Nanocarriers in the Rat Inner Ear After Intratympanic Administration

open access: yesNanoscale Research Letters, 2017
Liposome nanocarriers (LPNs) are potentially the future of inner ear therapy due to their high drug loading capacity and efficient uptake in the inner ear after a minimally invasive intratympanic administration.
Jing Zou   +4 more
doaj   +1 more source

Autophagy in the Vertebrate Inner Ear [PDF]

open access: yesFrontiers in Cell and Developmental Biology, 2017
Autophagy is a conserved catabolic process that results in the lysosomal degradation of cell components. During development, autophagy is associated with tissue and organ remodeling, and under physiological conditions it is tightly regulated as it plays a housekeeping role in removing misfolded proteins and damaged organelles.
Marta Magariños   +9 more
openaire   +6 more sources

Manufacturing and in vivo inner ear visualization of MRI traceable liposome nanoparticles encapsulating gadolinium

open access: yesJournal of Nanobiotechnology, 2010
Background Treatment of inner ear diseases remains a problem because of limited passage through the blood-inner ear barriers and lack of control with the delivery of treatment agents by intravenous or oral administration. As a minimally-invasive approach,
Kinnunen Paavo KJ   +6 more
doaj   +1 more source

Functional anatomy of the middle and inner ears of the red fox, in comparison to domestic dogs and cats

open access: yes, 2020
Anatomical middle and inner ear parameters are often used to predict hearing sensitivities of mammalian species. Given that ear morphology is substantially affected both by phylogeny and body size, it is interesting to consider whether the relatively ...
Burda, H., Malkemper, E., Mason, M.
core   +1 more source

Asymmetrically severe internal auditory canal hypoplasia: A case report. [PDF]

open access: yes, 2020
We present a case of an otherwise healthy 20-month-old with congenital sensorineural hearing loss. CT and MR imaging demonstrated bilateral asymmetrically severe hypoplasia of the internal auditory canals and vestibulocochlear nerves.
Djalilian, Hamid R   +6 more
core   +1 more source

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