Results 61 to 70 of about 434,910 (305)

Surgical procedure of intratympanic injection and inner ear pharmacokinetics simulation in domestic pigs

open access: yesFrontiers in Pharmacology
Introduction: One major obstacle in validating drugs for the treatment or prevention of hearing loss is the limited data available on the distribution and concentration of drugs in the human inner ear.
Adele Moatti   +18 more
doaj   +1 more source

Polymer‐Incorporated Mechanically Compliant Carbon Nanotube Microelectrode Arrays for Multichannel Neural Signal Recording

open access: yesAdvanced Functional Materials, EarlyView.
This work presents a soft microelectrode array based on vertically aligned carbon nanotube (CNT) forests, combining high conductivity with mechanical softness. A densification process and air‐pressure‐assisted flexibilization improve structural integrity, ensuring stable insertion and reduced inflammation.
Hyeonhee Roh   +8 more
wiley   +1 more source

Probing the Xenopus laevis inner ear transcriptome for biological function

open access: yesBMC Genomics, 2012
Background The senses of hearing and balance depend upon mechanoreception, a process that originates in the inner ear and shares features across species.
Powers TuShun R   +3 more
doaj   +1 more source

Which GABA Receptors Are Expressed in the Zebrafish Lateral Line? [PDF]

open access: yes, 2017
The presence of the neurotransmitter GABA in the mammalian inner ear is well established, yet its role in regulating inner ear cell function is less clear.
Crabtree, Connell   +5 more
core   +1 more source

Inner ear ossification and mineralization kinetics in human embryonic development - microtomographic and histomorphological study. [PDF]

open access: yes, 2017
Little is known about middle and inner ear development during the second and third parts of human fetal life. Using ultra-high resolution Microcomputed Tomography coupled with bone histology, we performed the first quantitative middle and inner ear ...
Courbon, G.   +5 more
core   +1 more source

Cell Calcification Models and Their Implications for Medicine and Biomaterial Research

open access: yesAdvanced Healthcare Materials, EarlyView.
Calcification, is the process by which the tissues containing minerals are formed, occurring during normal physiological processes, or in pathological conditions. Here, it is aimed to give a comprehensive overview of the range of cell models available, and the approaches taken by these models, highlighting when and how methodological divergences arise,
Luke Hunter   +5 more
wiley   +1 more source

Beyond Bioactive Glass Composition: Using Morphology to Improve in Vitro and in Vivo Performance

open access: yesAdvanced Healthcare Materials, EarlyView.
Bioactive glasses can easily be shaped into granules, spheres, discs, fibers, or three‐dimensional scaffolds. The resulting morphology not only affects handling properties; it has a direct influence on various glass properties, including results of acellular immersion experiments or in vitro studies with cells or bacteria, but also on in vivo ...
Meixin Su   +5 more
wiley   +1 more source

Dual contribution to amplification in the mammalian inner ear

open access: yes, 2010
The inner ear achieves a wide dynamic range of responsiveness by mechanically amplifying weak sounds. The enormous mechanical gain reported for the mammalian cochlea, which exceeds a factor of 4,000, poses a challenge for theory.
A. J. Hudspeth   +4 more
core   +1 more source

Progressive Insights into 3D Bioprinting for Corneal Tissue Restoration

open access: yesAdvanced Healthcare Materials, EarlyView.
This review explores the potential of 3D bioprinting to replicate the complex structure and function of the human cornea. It highlights key advances in bioink development, printing modalities, and in vivo performance, while addressing current challenges and emerging strategies. The review emphasizes bioprinting's promise to overcome donor shortages and
Ilayda Namli   +6 more
wiley   +1 more source

Natural Sweetener Stevioside‐Based Dissolving Microneedles Solubilize Minoxidil for the Treatment of Androgenic Alopecia

open access: yesAdvanced Healthcare Materials, EarlyView.
This study addresses limitations of minoxidil (MXD) in treating androgenetic alopecia by using stevioside (STV) as a solubilizing agent and microneedle (MN) material. STV enhanced MXD's solubility and skin absorption, leading to improved drug delivery and significant hair regrowth in animal models, demonstrating strong potential for AGA treatment ...
Junying Zhang   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy