Results 71 to 80 of about 68,591 (217)

Phenotype characterization of heart failure with preserved ejection fraction in medical device and surgical trials

ESC Heart Failure, EarlyView.
This systematic review identified 24 clinical trials of medical device and surgical interventions for HFpEF, with 16 demonstrating at least safety and feasibility, but little evidence of long‐term benefit. Phenotype‐based responses suggest that certain interventions may benefit specific HFpEF subgroups, yet most trials suffered from heterogeneous ...
Kurdo Araz, Francesco Fioretti, Sara Ladak, Mohammed Obaidan, Javed Butler, Aamir Hameed   +5 more
wiley   +1 more source

Protective Effects of Buckwheat and Isoquercitrin Against Noise‐Induced Hearing Loss in Mice: An Antioxidant Strategy Targeting the Nrf2/HO‐1 Pathway in Auditory Hair Cells

Food Frontiers, EarlyView.
Isoquercitrin (IQ), a major bioactive compound in buckwheat (Fagopyrum esculentum Moench; BW), serves as a key mediator of the protective effects of BW against noise‐induced hearing loss (NIHL) by activating the Nrf2/HO‐1 signaling pathway, and oral administration of BW and IQ significantly attenuates oxidative stress and hair cell apoptosis through ...
Hojin Lee, Gahwa Jung, Guijae Yoo, Jonghoon Jung, Jae‐Yong Park, Changho Lee, Jaekwang Lee   +6 more
wiley   +1 more source

A Systematic Review of the Clinical Impact of Implementing Artificial Intelligence in Upper Aerodigestive Tract Endoscopy

Head &Neck, EarlyView.
ABSTRACT Background Endoscopy is essential in upper aerodigestive tract (UADT) examination, particularly in the early detection of laryngopharyngeal lesions. However, UADT endoscopy remains operator‐dependent and lacks standardized quality metrics. Recent advancements in artificial intelligence (AI) have generated interest in applications within UADT ...
Celine M. L. H. Wilmes, Arsen Goril BSc, Henri A. M. Marres, David J. Wellenstein, Guido B. van den Broek   +4 more
wiley   +1 more source

Evaluation of the Peripheral Vestibular System due to Inner Ear Barotrauma in the Hyperbaric Environment. [PDF]

Laryngoscope Investig Otolaryngol
Bozkurt Ö, Güven SG, Taş M, Yılmaz Ş, Köder A, Bulut E.   +5 more
europepmc   +1 more source

Using Flight Plan for Embolization Technique Based on Carotid Body Tumor Angiography to Improve Surgical Treatment of the Lesion: Report of Two Cases

Head &Neck, EarlyView.
ABSTRACT Background Carotid body tumor (CBT) is a rare type of paraganglioma in head and neck region, with a high risk of surgical bleeding and nerve damage. Here we applied a new imaging tool termed “Flight Plan for Embolization” (FPFE) technique to better identify tumors' feeding arteries so that better dissection and bleeding control can be made to ...
Haotian Huanggu, Guangchao Gu, Fangda Li, Rong Zeng, Yuehong Zheng   +4 more
wiley   +1 more source

Recent Advances in Functionalized Nanoparticles for Targeted and Controlled Inner Ear Therapy via Localized Cochlear Delivery. [PDF]

J Audiol Otol
Kim DK.
europepmc   +1 more source

The Many Facets of Workplace Moral Courage: Development and Validation of a Multidimensional Scale

Human Resource Development Quarterly, EarlyView.
ABSTRACT In the battle against unethical behavior in organizations, fostering employees' moral courage proves vital beyond conventional regulation and compliance efforts. To propel this frontier and empower individuals to uphold moral values, a robust measure of workplace moral courage becomes imperative.
Nicole Witt, Carmen Tanner
wiley   +1 more source

Assessment of Safety, Tolerability, Pharmacokinetics, and Volume-Dependent Conductive Hearing Loss in Healthy Volunteers: First-in-Human, Open-Label, Placebo-Controlled Study of a Single Intratympanic Injection of AC102. [PDF]

Otol Neurotol
Lanting C, Robijn S, Nieratschker M, Galetzka C, Meis A, Rommelspacher H, Ahoud-Schoenmakers S, Lackner E, Zeitlinger M, Bauer M, Arnoldner C, Pennings R, Schlingensiepen R.   +12 more
europepmc   +1 more source

Ongoing Discrepancy Between Unilateral Meniere's Disease and Bilateral Endolymphatic Hydrops on Hydrops MRI. [PDF]

Laryngoscope Investig Otolaryngol
Yang TH, Meng LC, Young YH.
europepmc   +1 more source

Toxicities in long‐term survivors of head and neck cancer—A multi‐national cross‐sectional analysis

International Journal of Cancer, EarlyView.
What's New? Cancer treatments frequently have toxic effects on the body, and these toxicities may cause long‐term health issues. Here, the authors report the results of a large, international study to evaluate long‐term toxicities of treatment for head and neck cancer (HNC).
Katherine J. Taylor, Cecilie D. Amdal, Kristin Bjordal, Guro L. Astrup, Bente B. Herlofson, Fréderic Duprez, Ricardo R. Gama, Alexandre Jacinto, Eva Hammerlid, Melissa Scricciolo, Femke Jansen, Irma M. Verdonck‐de Leeuw, Giuseppe Fanetti, Orlando Guntinas‐Lichius, Johanna Inhestern, Tatiana Dragan, Alexander Fabian, Andreas Boehm, Ulrike Wöhner, Naomi Kiyota, Maximilian Krüger, Pierluigi Bonomo, Monica Pinto, Sandra Nuyts, Joaquim Castro Silva, Carmen Stromberger, Pol Specenier, Francesco Tramacere, Ayman Bushnak, Pietro Perotti, Michaela Plath, Alberto Paderno, Noa Stempler, Maria Kouri, Vincent Grégoire, Silke Tribius, Susanne Singer, on behalf of the EORTC Quality of Life Group and the EORTC Head and Neck Group   +37 more
wiley   +1 more source