Results 71 to 80 of about 438,577 (299)

Dual contribution to amplification in the mammalian inner ear

, 2010
The inner ear achieves a wide dynamic range of responsiveness by mechanically amplifying weak sounds. The enormous mechanical gain reported for the mammalian cochlea, which exceeds a factor of 4,000, poses a challenge for theory.
A. J. Hudspeth, J. Lighthill, L. Robles, M. A. Ruggero, Tobias Reichenbach   +4 more
core   +1 more source

Moth‐Wing‐Inspired Multifunctional Metamaterials

Advanced Materials, EarlyView.
This study develops a moth‐wing‐inspired heterogeneous metamaterial that achieves synergistic broadband sound absorption, mechanical energy dissipation, and thermal insulation within a lightweight architected framework. Combining bioinspired gradient design, genetic‐algorithm optimization, and additive manufacturing, the bionic heterogeneous acoustic ...
Haoran Pei, Hang Yang, Ning Zhang, Tian Li, Xinxin Wang, Miao Zhao, Shuwei Ding, Xin Wang, Qinniu Lv, Zijie Xu, Yinghong Chen, Xinwei Li, Wei Zhai   +12 more
wiley   +1 more source

Roles of supporting cells in the maintenance and regeneration of the damaged inner ear: A literature review

Journal of Otology
The inner ear sensory epithelium consists of two major types of cells: hair cells (HCs) and supporting cells (SCs). Critical functions of HCs in the perception of mechanical stimulation and mechanosensory transduction have long been elucidated.
Jing-Ying Guo, Jun-Yi Xu, Shu-Sheng Gong, Guo-Peng Wang   +3 more
doaj   +1 more source

Inner Ear Therapeutics: An Overview of Middle Ear Delivery

Frontiers in Cellular Neuroscience, 2019
There are a variety of methods to access the inner ear and many of these methods depend on utilizing the middle ear as a portal. In this approach the middle ear can be used as a passive receptacle, as part of an active drug delivery system, or simply as ...
Jaimin Patel, Mikhaylo Szczupak, Suhrud Rajguru, Suhrud Rajguru, Carey Balaban, Michael E. Hoffer, Michael E. Hoffer   +6 more
doaj   +1 more source

Sufu and Gli3 repressor mediate the temporal basal-to-apical progression of hair cell differentiation in mammalian cochleae [PDF]

, 2014
Poster presentation - Theme 3: Development & stem cellsThe Sonic Hedgehog pathway plays important roles in mammalian inner ear development. Mutations of Shh, Smo and Gli3 lead to severe defects in mouse inner ear morphogenesis.
Hui, CC, Liu, Y, Sham, MH, Wang, B, Wong, EYM   +4 more
core  

Plastin 1 widens stereocilia by transforming actin filament packing from hexagonal to liquid [PDF]

, 2016
With their essential role in inner-ear function, stereocilia of sensory hair cells demonstrate the importance of cellular actin protrusions. Actin packing in stereocilia is mediated by crosslinkers of the plastin, fascin, and espin families.
Avenarius, Burkard, Chhabra, Claessens, Cox, Cox, Crawley, DeRosier, DeRosier, DeRosier, DeRosier, Drummond, Dumont, Ebrahim, Egelman, Eng, Erde, Francis, Gallien, Gardel, Gillespie, Grimm-Günter, Grüneberg, Gupton, Gustafsson, Hudspeth, Hwang, Jansen, Jones, Jones, Jones, Krey, Krey, Li, Merritt, Michelot, Mogensen, Perrin, Perrin, Purdy, Revenu, Rzadzinska, Salles, Sekerková, Shepherd, Shevchenko, Shin, Shin, Shin, Taylor, Tilney, Tilney, Tilney, Tilney, Tilney, Vignjevic, Volkmann, Waingeh, Wilmarth, Zheng   +59 more
core   +2 more sources

Scalable Etch‐Free Transfer of Low‐Dimensional Materials From Metal Films to Diverse Substrates

Advanced Materials Interfaces, EarlyView.
A scalable, etch‐free transfer method for low‐dimensional materials is presented, utilizing a low‐melting‐point metal as a reusable support. This technique enables gentle wafer‐scale electrochemical delamination from mechanically fragile metal thin‐film substrates and supports integration into device architectures.
Kentaro Yumigeta, Muhammed Yusufoglu, Mamun Sarker, Rishi Raj, Franco Daluisio, Richard Holloway, Howard Yawit, Thomas Sweepe, Julian Battaglia, Shelby Janssen, Alex C. Welch, Paul DiPasquale, K. Andre Mkhoyan, Alexander Sinitskii, Zafer Mutlu   +14 more
wiley   +1 more source

Connexins and gap junctions in the inner ear - it's not just about K(+) recycling [PDF]

, 2014
Normal development, function and repair of the sensory epithelia in the inner ear are all dependent on gap junctional intercellular communication.
Forge, A, Jagger, DJ
core   +2 more sources

4D Bioprinted Self‐Folding Scaffolds Enhance Cartilage Formation in the Engineering of Trachea

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
A bilayer self‐folding scaffold, triggerable by humidity, is fabricated via 4D bioprinting for trachea engineering. An analytical model is derived to predict its radius of curvature, enabling its scalability. Cartilage progenitor cells seeded on the scaffold perceive scaffold final curvature and react to it, by enhancing the upregulation of pro ...
Irene Chiesa, Alessio Esposito, Giovanni Vozzi, Riccardo Gottardi, Carmelo De Maria   +4 more
wiley   +1 more source

Cochlear Implant Outcomes and Genetic Mutations in Children with Ear and Brain Anomalies [PDF]

, 2015
Background. Specific clinical conditions could compromise cochlear implantation outcomes and drastically reduce the chance of an acceptable development of perceptual and linguistic capabilities.
Aimoni, C, Busi, M, Calzolari, F, Castiglione, Alessandro, Granieri, E, Martini, Alessandro, Minazzi, F, Rosignoli, M, Trevisi, Patrizia   +8 more
core   +4 more sources