Results 61 to 70 of about 5,362,575 (211)
Atypical antipsychotics in the treatment of early-onset schizophrenia
, 2015 Michal Hrdlicka, Iva Dudova Department of Child Psychiatry, Charles University Second Faculty of Medicine and University Hospital Motol, Prague, Czech Republic Abstract: Atypical antipsychotics (AAPs) have been successfully used in early-onset ...
Dudova I, Hrdlicka M
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Early-onset AGA modifies drug effects.
BackgroundEarly-onset androgenetic alopecia (AGA) has been associated with various chronic conditions, including metabolic syndrome (MetS). Gaining a deep understanding of early-onset AGA may enable earlier intervention in individuals at high risks. This
Li-Ping Liu (3590765) +5 more
core +1 more source
Genetic Analysis ofRAB39Bin an Early-Onset Parkinson's Disease Cohort
, 2020 Pathogenic variants in the gene encoding RAB39B, resulting in the loss of protein function, lead to the development of X-linked early-onset parkinsonism.
Romano, Alexandra +6 more
core +1 more source
Is major depressive disorder with psychotic features more likely in elderly than adulthood?
Psychiatry and Behavioral Sciences, 2015 Objective: Although psychotic depression is very common among old depressed patients, studies have generally failed to find any socio-demographic differences between psychotic depressed patients and non-psychotic patients.
Osman Ozdemir +4 more
doaj +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Early – versus late-onset preeclampsia: differences in risk factors and birth outcomes
, 2017 Introduction. Preeclampsia (PE) continues to be a leading cause of maternal and fetal morbidity and mortality worldwide with an incidence of 3–5 %. Recently evidence suggests that PE can be subdivided into early-onset PE (EOP), requiring delivery before ...
Medvyedyeva O., Markin L.
core +1 more source
Is Parkinson's disease of early onset a separate disease entity? [PDF]
, 1989 Two groups of patients suffering from Parkinson's disease were studied. The first group consisted of 23 patients with an onset age before 40 years; in the second group of 21 patients the onset was after age 50. The clinical findings and the course of the
Ludin, Hans-Peter, Ludin, Sabina
core +2 more sources
The increasing burden of early-onset pancreatic and biliary tract cancers: a review of risk factors
ESMO Gastrointestinal OncologyThe rising incidence of early-onset pancreatic and biliary tract cancers (PBTCs) challenges conventional assumptions that these malignancies primarily affect older populations.
A. Boilève +6 more
doaj +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
A shared journey: insights from the Banksia Younger Onset Dementia Support Group [PDF]
, 2015 The study of a pilot program to support people with younger onset dementia in the Frankston area of outer Melbourne has found that the participants valued being involved in initiating and organising activities that they find meaningful and enjoyable, and
Seuwandi Wickramasinghe +2 more
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