Results 81 to 90 of about 5,362,575 (211)

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Early-onset sepsis events per 1000 live births.

, 2019
Early-onset sepsis events per 1000 live births.
Elise Putt (6555872), Kathryn Braye (6555866), John Ferguson (79508), Mark Jones (233817), Maralyn Foureur (3661378), Koert de Waal (6555869)   +5 more
core   +1 more source

Early-onset drinking in Ireland: negative outcomes and behaviours.

, 2013
Early-onset drinking in Ireland: negative outcomes and ...
Theodore D. Cosco (7937204), Karen Morgan (7895711), Hannah Mc Gee (7895552), Laura Currie (7937849)   +3 more
core   +2 more sources

The global burden and trends analysis of early-onset colorectal cancer attributable to dietary risk factors in 204 countries and territories, 1990–2019: a secondary analysis for the global burden of disease study 2019

Frontiers in Nutrition
BackgroundRising trends in early-onset colorectal cancer (CRC) burden have been observed, but the distribution and temporal patterns of early-onset CRC attributable to dietary risks remain unclear.ObjectivesThis study aimed to estimate the burden of ...
Jiao Su, Yuanhao Liang, Xiaofeng He
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Disorders Leading to Early-Onset Osteoarthritis: Orthopedic Considerations and Insights

Osteoarthritis (OA), characterized by articular cartilage deterioration, is influenced by factors such as age, trauma, genetic alterations, and inflammatory diseases. Early-onset osteoarthritis (EO-OA), typically observed before 40 or 50, can result from
Ahmet Issın, ISSIN, AHMET, ISSIN, GİZEM, Gizem Issın   +3 more
core   +1 more source

Early surgery for acute-onset infective endocarditis

, 2018
Objectives: Acute onset of infective endocarditis has been previously linked to the development of septic shock and a worse prognosis. The purpose of this study was to analyse the clinical features and in-hospital evolution of patients with acute-onset ...
Manuel Carnero-Alcázar, Ferrera, Carlos, Di Stefano, Salvatore, Cristina Sarriá, Luis Carlos Maroto Castellanos, Javier Cobiella, Maroto Castellanos, Luis Carlos, David Vivas, Sarriá, Cristina, Vivas Balcones, Luis David, Daniel García-Arribas, Cobiella, Javier, García Arribas, Daniel, Carlos Ferrera, Isidre Vilacosta, Carmen Olmos, Fernández, Cristina, Carmen Sáez, Carnero Alcázar, Manuel, Cristina Fernández, Javier López, López, Javier, Sáez, Carmen, San Román, José Alberto, Olmos, Carmen, Vila Costa, Isidro, Salvatore Di Stefano, J Alberto San Román   +27 more
core   +1 more source

TBK1 mutation spectrum in an extended European patient cohort with frontotemporal dementia and amyotrophic lateral sclerosis [PDF]

, 2017
We investigated the mutation spectrum of the TANK-Binding Kinase 1 (TBK1) gene and its associated phenotypic spectrum by exonic resequencing of TBK1 in a cohort of 2,538 patients with frontotemporal dementia (FTD), amyotrophic lateral sclerosis (ALS), or
Gelpi, Ellen, Lle\uf3, Alberto, Alexopoulos, Panagiotis, Engelborghs, Sebastiaan, Diehl-Schmid, Janine, Cras, Patrick, Sch\uf6ls, Ludger, Bäumer, Veerle, Gómez-Tortosa, Estrella, Gijselinck, Ilse, Santens, PatrickGE34UZGent8010010118870000-0002-8886-9776F4E5680A-F0ED-11E1-A9DE-61C894A0A6B4, Santens, Patrick, Schöls, Ludger, Clarimón, Jordi, Cruts, Marc, G\uf3mez-Tortosa, Estrella, Just, Jennifer, Danek, Adrian, Perrone, Federica, Sarafov, Stayko, Jordanova, Albena, Thonberg, H\ue5kan, Belgian Neurology Consortium, the, Sleegers, Kristel, Ramirez, Alfredo, Jessen, Frank, Tournev, Ivailo, Heeman, Bavo, Heneka, Michael T., Vandenberghe, Rik, van der Zee, Julie, Graff, Caroline, Rojas-García, Ricardo, Dillen, Lobke, Rojas-Garci\ue1, Ricardo, Miltenberger-Milt\ue9nyi, Gabriel, Miltenberger-Miltényi, Gabriel, Synofzik, Matthis, Simões do Couto, Frederico, De Jonghe, Peter, Lleó, Alberto, Dermaut, Bart, Clarim\uf3n, Jordi, De Bleecker, Jan, B\ue4umer, Veerle, de Mendonça, Alexandre, Dillen, Lubina, Dermaut, BartGE31UZGent8020012288050000-0002-6968-057275FD8022-0C13-11E2-AA3C-3DCD10BDE39D, De Deyn, Peter P, Perneczky, Robert, Padovani, Alessandro, De Bleecker, JanGE34UZGent8010006203520000-0002-1328-1812F43740E0-F0ED-11E1-A9DE-61C894A0A6B4, Van Mossevelde, Sara, Baets, Jonathan, Borroni, Barbara, De Deyn, Peter Paul, Van Broeckhoven, Christine, Heneka, Michael T, Thonberg, Håkan   +58 more
core   +1 more source

بررسی مقایسه‌ای اتیولوژی سوش‌های باکتریایی در پنومونی وابسته به ونتیلاتور زودرس و دیررس در بیماران اورژانسی و غیر اورژانسی بستری در بخش‌های مراقبت ویژه‌ی بیمارستان الزهرای (س) اصفهان

مجله دانشکده پزشکی اصفهان, 2015
مقدمه: پنومونی وابسته به ونتیلاتور، شایع‌ترین عفونت در بخش مراقبت‌های ویژه می‌باشد که به دو نوع زودرس و دیررس تقسیم می‌گردد. میزان بروز و مرگ و میر بیماران در نوع دیررس، دارای پیش‌آگهی بدتری است و سوش‌های باکتریایی مربوط به آن نیز دیرتر به درمان پاسخ می ...
Babak Alikiaie, Daryoush Moradi, Maryam Mosaddegh, Nima Salimi, Jamshid Mosaddegh   +4 more
doaj  

Comparing survival outcomes between surgical and non-surgical treatments in patients with early-onset endometrial cancer and developing a nomogram to predict survival: a study based on Eastern and Western data sets

World Journal of Surgical Oncology
Background Surgery is the preferred approach for treating endometrial cancer (EC). However, the prognosis of young women undergoing surgery has not been thoroughly evaluated.
Yunfeng Zheng, Ran Hu, Fan Yang, Gaohua Liu, Tianyu Peng, Langting Xie, Jie Wu, Lamei Hou, Rui Yuan   +8 more
doaj   +1 more source