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Early life stress impairs hippocampal subfield myelination [PDF]
Communications BiologyThe hippocampus is an archicortical structure that is highly sensitive to experience and is made up of individual subfields. These subfields, crucial for learning and memory, rapidly develop and are vulnerable to early stress, yet the mechanisms are ...
Emily S. Nichols +5 more
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Early Life Stress and Pediatric Posttraumatic Stress Disorder [PDF]
Brain Sciences, 2020 Traumatic stress exposure during critical periods of development may have essential and long-lasting effects on the physical and mental health of individuals.
Panagiota Pervanidou +3 more
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Adverse effects of early-life stress: focus on the rodent neuroendocrine system
Neural Regeneration Research, 2023 Early-life stress is associated with a high prevalence of mental illnesses such as post-traumatic stress disorders, attention-deficit/hyperactivity disorder, schizophrenia, and anxiety or depressive behavior, which constitute major public health problems.
Seung Hyun Lee, Eui-Man Jung
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Early Life Stress, Hormones, and Neurodevelopmental Disorders
Hormone Research in Paediatrics, 2022 Background: Early life stress (ELS) describes a broad spectrum of adverse and stressful prenatal events, namely, prenatal maternal stress (PMS), or early postnatal events, which can have detrimental long-term influences on the physiology, cognition, and ...
G. Makris +2 more
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Early life stress and development: potential mechanisms for adverse outcomes
Journal of Neurodevelopmental Disorders, 2020 Background Chronic and/or extreme stress in early life, often referred to as early adversity, childhood trauma, or early life stress, has been associated with a wide range of adverse effects on development.
Karen E. Smith, Seth D. Pollak
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Early Life Stress, Mood, and Anxiety Disorders [PDF]
Chronic Stress, 2017 Early life stress has been shown to exert profound short- and long-term effects on human physiology both in the central nervous system and peripherally. Early life stress has demonstrated clear association with many psychiatric disorders including major ...
Shariful A. Syed, Charles B. Nemeroff
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Alteration of somatosensory response in adulthood by early life stress. [PDF]
Frontiers in Molecular Neuroscience, 2015 Early-life stress is well known as a critical risk factor for mental and cognitive disorders in adulthood. Such disorders are accompanied by altered neuro- (synapto-) genesis and gene expression.
Yusuke eTakatsuru, Noriyuki eKoibuchi
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Early life stress concept: introduction
European Journal of Psychotraumatology, 2012 Rationale/statement of the problem : Stressful experiences during early life can remodel brain circuitry underlying behavioral adaptation with consequences for resilience and vulnerability to emotional and cognitive disorders. At least in the rodent this
E. Ronald de Kloet +1 more
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Impact of Early Life Stress on Reward Circuit Function and Regulation
Frontiers in Psychiatry, 2021 Early life stress – including experience of child maltreatment, neglect, separation from or loss of a parent, and other forms of adversity – increases lifetime risk of mood, anxiety, and substance use disorders.
Jamie L. Hanson +3 more
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Early-life neighborhood context, perceived stress, and preterm birth in African American Women [PDF]
SSM: Population Health, 2019 Stressors from multiple sources, across the life-course, may have independent and joint associations with preterm birth (PTB) risk in African American women. Using data from the Life-course Influences on Fetal Environments Study (LIFE; 2009–2011) of post-
Shawnita Sealy-Jefferson +2 more
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