Results 21 to 30 of about 4,035,262 (238)
Dissecting early life stress-induced adolescent depression through epigenomic approach
Molecular Psychiatry, 2022 Early life stress (ELS), such as abuse and neglect during childhood, can lead to psychiatric disorders in later life. Previous studies have suggested that ELS can cause profound changes in gene expression through epigenetic mechanisms, which can lead to ...
S. Ochi, Yogesh Kumar Dwivedi
semanticscholar +1 more source
Early life stress impairs synaptic pruning in the developing hippocampus
Brain, behavior, and immunity, 2022 Early life adversity impairs normal hippocampal function and connectivity in various mammalian species, including humans and rodents. According to the ‘cumulative model’ the number of early adversities can be summed up to determine the risk for ...
Kiran K. Dayananda +5 more
semanticscholar +1 more source
Early-life adversity and edentulism among Chinese older adults
BMC Oral Health, 2022 Background Emerging evidence indicate the relationship between ELA with oral health problems. However, most focus on single types of adversity. The association of cumulative ELA with edentulism, the final marker of disease burden for oral health, remains
Ziqing Tang +4 more
doaj +1 more source
Early life stress and psychopharmacology [PDF]
Psychopharmacology, 2011 The concept of early life stress (ELS) has long been a central focus in clinical psychiatry and psychology, owing in no small part to the primacy of this concept in psychoanalytic theory. Perhaps in response to that legacy, both clinical and preclinical biologically oriented researchers have become increasingly invested in understanding the adult ...
Lawrence H, Price, Thomas, Steckler
openaire +2 more sources
Clinical Psychology Review, 2021 Despite evidence supporting a role for oxytocin (OT) in regulating social behavior, surprisingly little is known about how this neuropeptide is calibrated during development.
B. Ellis +4 more
semanticscholar +1 more source
Why does early childhood deprivation increase the risk for depression and anxiety in adulthood? A developmental cascade model [PDF]
, 2020 Background: Using data from the English & Romanian Adoptees (ERA) study we recently reported that early time-lmited exposure to severe institutional deprivation is associated with early onset and persistent neurodevelopmental problems and later onset
Barker, Edward D. +10 more
core +1 more source
The effects of early life stress on impulsivity.
Neuroscience and Biobehavioral Reviews, 2022 Elevated impulsivity is a symptom shared by various psychiatric disorders such as substance use disorder, bipolar disorder, and attention-deficit/hyperactivity disorder.
Evelyn Ordoñes Sanchez, D. Bangasser
semanticscholar +1 more source
Epigenetic Programming by Early-Life Stress [PDF]
, 2018 Studies show that adverse conditions during early life can increase risks of developing mood disorders later in life. It is currently hypothesized that levels of environmental adversity in this early developmental period are able to shape the experience-dependent maturation of stress-regulating pathways leading to long-lasting alterations in stress ...
Reema Abdulrahman S, Alyamani +1 more
openaire +4 more sources
Testing three hypotheses about effects of sensitive-insensitive parenting on telomeres. [PDF]
, 2020 Telomeres are the protective DNA-protein sequences appearing at the ends of chromosomes; they shorten with each cell division and are considered a biomarker of aging.
Beijers, Roseriet +6 more
core +1 more source
Chronic unpredictable early-life stress (CUELS) protocol: Early-life stress changes anxiety levels of adult zebrafish [PDF]
Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2021 Early-life stress can lead to two different behavioral responses: (1) increased susceptibility to psychiatric disorders or (2) resilience. Here, we created a chronic unpredictable early-life stress (CUELS) protocol to assess the effects of early experiences in adult zebrafish.
Barbara D, Fontana +4 more
openaire +2 more sources