Results 31 to 40 of about 4,035,262 (238)

Early life maternal separation induces sex-specific antidepressant-like responses but has minimal effects on adult stress susceptibility in mice

Frontiers in Behavioral Neuroscience, 2022
Early life stress is known to increase the risk of depression and anxiety disorders, which are highly prevalent conditions that disproportionately affect women.
Brittany J. Baugher, Benjamin D. Sachs
doaj   +1 more source

Stress exposure in early post-natal life reduces telomere length: an experimental demonstration in a long-lived seabird [PDF]

, 2014
Exposure to stressors early in life is associated with faster ageing and reduced longevity. One important mechanism that could underlie these late life effects is increased telomere loss. Telomere length in early post-natal life is an important predictor
Adam, Aileen, Boner, Winnie, Daunt, Francis, Heidinger, Britt J., Herborn, Katherine A., Monaghan, Pat, Noguera, Jose C.   +6 more
core   +4 more sources

N-3 Polyunsaturated Fatty Acids (PUFAs) Reverse the Impact of Early-Life Stress on the Gut Microbiota [PDF]

, 2015
Supporting Information S1 File. Microbiota Data Set. NS.S, NS.LD, NS.HD stand for non-separated Saline, non-separated Low Dose, non-separated High Dose, respectively.
Cotter, Paul D., Crispie, Fiona, Cryan, John F., Dinan, Timothy G., El Aidy, Sahar, Kelly, Philip, O'Sullivan, Orla, Pusceddu, Matteo M, STANTON, CATHERINE   +8 more
core   +3 more sources

From traumatic childhood to cocaine abuse: the critical function of the immune system [PDF]

, 2018
Background: Experiencing traumatic childhood is a risk factor for developing substance use disorder (SUD), but the mechanisms that underlie this relationship have not been determined.
Aricò, Eleonora, Bussone, Silvia, Carola, Valeria, Casella, Pietro, Catale, Clarissa, Chiurchiù, Valerio, Di Sabato, Paola, D’Argenio, Alberto, Guatteo, Ezia, Lo Iacono, Luisa, Maccarrone, Mauro, Martini, Alessandro, Mercuri, Nicola B., Perrone, Fabiana, Puglisi-Allegra, Stefano, Troisi, Alfonso, Valzania, Alessandro, Viscomi, Maria Teresa   +17 more
core   +1 more source

Cortisol reactivity to psychosocial stress is greater in sexual risk takers [PDF]

, 2013
Several studies have reported an association between deviant behaviour and cortisol reactivity to stress. However relatively few studies have investigated the relationship between psychobiological stress reactivity and sexual risk taking behaviours.
Harrison, Claire, Mitchell, Melanie, Ratcliffe, Joanne, Smith, Michael   +3 more
core   +1 more source

Reduced Oligodendrocyte Precursor Cell Impairs Astrocytic Development in Early Life Stress

Advancement of science, 2021
Astrocyte maldevelopment is implicated in various neuropsychiatric diseases associated with early life stress. However, the underlying astrocytopathy mechanism, which can result in the psychiatric symptoms, remains unclear.
Yuxin Wang, Yixun Su, Guangdan Yu, Xiaorui Wang, Xiaoying Chen, Bin Yu, Yijun Cheng, Ruixue Li, J. Sáez, Chenju Yi, L. Xiao, Jianqin Niu   +11 more
semanticscholar   +1 more source

The interplay of early-life stress, nutrition and immune activation programs adult hippocampal structure and function

Frontiers in Molecular Neuroscience, 2015
Early-life adversity increases the vulnerability to develop psychopathologies and cognitive decline later in life. This association is supported by clinical and preclinical studies.
Lianne eHoeijmakers, Paul eLucassen, Aniko eKorosi   +2 more
doaj   +1 more source

High-resolution 3D weld toe stress analysis and ACPD method for weld toe fatigue crack initiation [PDF]

, 2019
Weld toe fatigue crack initiation is highly dependent on the local weld toe stress-concentrating geometry including any inherent flaws. These flaws are responsible for premature fatigue crack initiation (FCI) and must be minimised to maximise the fatigue
Chaudhuri, Somsubhro, Crump, J., Mellor, B. G., Reed, P. A. S.   +3 more
core   +2 more sources

Effect of Early Life Stress on the Epigenetic Profiles in Depression

Frontiers in Cell and Developmental Biology, 2020
Depression is one of the most common mental disorders and has caused an overwhelming burden on world health. Abundant studies have suggested that early life stress may grant depressive-like phenotypes in adults. Childhood adversities that occurred in the
Ming Li, Xiying Fu, Wei Xie, Wanxu Guo, Bingjin Li, Ranji Cui, Wei Yang   +6 more
doaj   +1 more source

Oxidative Dysregulation in Early Life Stress and Posttraumatic Stress Disorder: A Comprehensive Review

Brain Science, 2021
Traumatic stress may chronically affect master homeostatic systems at the crossroads of peripheral and central susceptibility pathways and lead to the biological embedment of trauma-related allostatic trajectories through neurobiological alterations even
E. Karanikas, N. Daskalakis, A. Agorastos   +2 more
semanticscholar   +1 more source