The research carried out in 2009 in the multicultural site Gnidavs'ka Gìrka near Łuck [PDF]
У статті проаналізовано результати досліджень на багатошаровому поселенні Гнідавська Гірка с.Рованці: на площі 636,5 кв.м. виявлено і досліджено 50 археологічних об'єктів від епохи неоліту до пізнього середньовіччяThe article presents the effects of the ...
Bardetskyi, Andrii +3 more
core
Hematopoietic (stem) cells—The elixir of life?
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Os agentes públicos e a fome nos primeiros séculos da Idade Média
Resumo A Alta Idade Média foi um período marcado por sucessivas crises alimentares. De acordo com um levantamento nas histórias, anais, crônicas, hagiografias etc., feito no início do século XX pelo historiador alemão Fritz Curschmann, há 68 menções a ...
Marcelo Cândido da Silva
doaj +1 more source
Cost Accounting in Early Regulated Markets: The Case of the Royal Soap Factory of Seville, 1525-1692 [PDF]
(WP 16/03 Clave pdf) Regulated markets and state-owned monopolies characterized the economies of many Southern European territories around the end of the Middle Ages and during the Renaissance.
SALVADOR CARMONA
core
Detrital zircon from a late Paleozoic accretionary complex of SW Iberia (Variscan Belt): History of crustal growth and recycling at the Rheic convergent margin [PDF]
In this study we present new U-Pb ages of detrital zircons from greywackes and quartzites of the Pulo do Lobo Anticline (PLA) that have been interpreted to represent a Late Paleozoic accretionary complex in SW Iberia.
Chichorro, M. +4 more
core
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
The Preventive Check in Medieval and Pre-industrial England [PDF]
England’s post-Reformation demographic regime has been characterized as ‘low pressure’. Yet the evidence hitherto for the presence of a preventive check, defined as the short-run response of marriage and births to variations in living standards, is ...
Cormac Ó Gráda, Morgan Kelly
core
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Different Approach to Horses-The Use of Equid Remains in the Early Middle Ages on the Example of Ostrów Tumski in Wroclaw. [PDF]
Jaworski K +3 more
europepmc +1 more source
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source

