Results 111 to 120 of about 2,848,670 (398)
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Different Approach to Horses-The Use of Equid Remains in the Early Middle Ages on the Example of Ostrów Tumski in Wroclaw. [PDF]
Jaworski K +3 more
europepmc +1 more source
Detrital zircon from a late Paleozoic accretionary complex of SW Iberia (Variscan Belt): History of crustal growth and recycling at the Rheic convergent margin [PDF]
In this study we present new U-Pb ages of detrital zircons from greywackes and quartzites of the Pulo do Lobo Anticline (PLA) that have been interpreted to represent a Late Paleozoic accretionary complex in SW Iberia.
Chichorro, M. +4 more
core
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Cumulative Blood Pressure in Early Adulthood and Coronary Artery Calcium and Carotid Intima‐Media Thickness in Middle Age Among Adults With Maintained Blood Pressure of <130/80 mm Hg: A Post Hoc Analysis [PDF]
Soroush Masrouri +4 more
openalex +1 more source
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
The Preventive Check in Medieval and Pre-industrial England [PDF]
England’s post-Reformation demographic regime has been characterized as ‘low pressure’. Yet the evidence hitherto for the presence of a preventive check, defined as the short-run response of marriage and births to variations in living standards, is ...
Cormac Ó Gráda, Morgan Kelly
core
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source

