Results 101 to 110 of about 4,966,709 (244)

Spacelike Geodesics and Other Puzzles in the Mixmaster Universe [PDF]

open access: yes, 2012
In this thesis we are going to investigate the behaviour of geodesics in a metric with a singularity known as the ``Mixmaster Universe''. This was motivated from previous work done, where the now well-known AdS/CFT correspondence was used to extract ...
KENWAY, ANGHARAD,SONIA   +1 more
core  

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

STRUCTURE OF THE UNIVERSE

open access: yes, 2020
Between 1840 and 1864 Jakob Lorber wrote 25 volumes which was dictated to him through the inner word. The aim of these books is to re-explain to mankind the true meaning of religion and the purpose of life. Among the many deepest secrets of life, a clear
Hoffmann, Albert
core  

Probing the primordial Universe using the SKA in combination with other cosmological surveys [PDF]

open access: yes, 2019
>Magister Scientiae - MScNext-generation surveys of the large-scale structure of the Universe will be of great importance in allowing us to extract invaluable information about the nature of the Universe and the physical laws that govern it, at a ...
Matthewson, William
core   +1 more source

What happens when supercooling is terminated by curvature flipping of the effective potential?

open access: yesJournal of High Energy Physics
We explore the nature of a certain type of supercooled phase transition, where the supercooling is guaranteed to end due to the curvature of the finite-temperature effective potential at the origin experiencing a sign flip at some temperature.
Tomasz P. Dutka   +2 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Applications of cosmological perturbation theory [PDF]

open access: yes, 2011
PhDCosmological perturbation theory is crucial for our understanding of the universe. The linear theory has been well understood for some time, however developing and applying the theory beyond linear order is currently at the forefront of research in
Christopherson, Adam J.
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

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