Results 91 to 100 of about 1,185,812 (300)

A JavaScript API for the Ice Sheet System Model: towards on online interactive model for the Cryosphere Community [PDF]

, 2016
. Earth System Models (ESMs) are becoming increasingly complex, requiring extensive knowledge and experience to deploy and use in an efficient manner.
Cheng, Daniel, Duong, Bao, Halkides, Daria, Harounian, Silva, Hayes, Wayne, Larour, Eric, Morlighem, Mathieu, Nguyen, Lan, Perez, Gilberto, Petrie, Kit, Quinn, Justin   +10 more
core  

Habitability of Super-Earth Planets around Main-Sequence Stars including Red Giant Branch Evolution: Models based on the Integrated System Approach

, 2011
In a previous study published in Astrobiology, we focused on the evolution of habitability of a 10 M_E super-Earth planet orbiting a star akin to the Sun.
C. Bounama, Cuntz, K.-P. Schröder, M. Cuntz, Maeder, Noack, S. Franck, Schaller, W. von Bloh   +8 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Editorial: Ecological Applications of Earth System Models and Regional Climate Models

Frontiers in Marine Science, 2021
Rebecca G. Asch, Johnna M. Holding, Darren J. Pilcher, Darren J. Pilcher, Sara Rivero-Calle, Kenneth A. Rose   +5 more
doaj   +1 more source

Ripples of Learning: A Middle School Teacher's Application of Content and Pedagogy Learned in the ESSEA Online Earth System Science Course [PDF]

This article provides an overview of an Earth System Science Education Alliance (ESSEA) online professional development course for middle school classroom teachers.
Kelly Kunk, Robert Myers, William Slattery   +2 more
core   +1 more source

DSCOVR EPIC vegetation earth system data record: product analysis and scientific exploration [PDF]

, 2018
The NASA's Earth Polychromatic Imaging Camera (EPIC) onboard NOAA's Deep Space Climate Observatory (DSCOVR) mission was launched on February 11, 2015 to the Sun-Earth Lagrangian L1 point where it began to collect radiance data of the entire sunlit Earth ...
Knjazihhin, Juri, Mõttus, Matti, Pisel, Jan, Rautiainen, Miina, She, Xiaojun   +4 more
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Detectability of Phytoplankton Biomass Extremes Using Simulated Satellite Chlorophyll Observations

Geophysical Research Letters
Extreme open‐ocean phytoplankton events can influence marine ecosystems, yet their global occurrence, drivers, and consequences remain poorly understood.
Genevieve L. Clow, Nicole S. Lovenduski, Michael N. Levy, Keith Lindsay, Samuel C. Mogen, Jennifer E. Kay   +5 more
doaj   +1 more source

Modular System for Shelves and Coasts (MOSSCO v1.0) - a flexible and multi-component framework for coupled coastal ocean ecosystem modelling

, 2017
Shelf and coastal sea processes extend from the atmosphere through the water column and into the sea bed. These processes are driven by physical, chemical, and biological interactions at local scales, and they are influenced by transport and cross strong
Burchard, Hans, Hofmeister, Richard, Kerimoglu, Onur, Klingbeil, Knut, Kösters, Frank, Lemmen, Carsten, Nasermoaddeli, M. Hassan, Wirtz, Kai W.   +7 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source