Delayed Disease Progression in Cynomolgus Macaques Infected with Ebola Virus Makona Strain
In late 2013, the largest documented outbreak of Ebola hemorrhagic fever started in Guinea and has since spread to neighboring countries, resulting in almost 27,000 cases and >11,000 deaths in humans.
Andrea Marzi+5 more
doaj +1 more source
Hierarchy of knowledge translation: from health problems to ad-hoc drug design [PDF]
An innovative approach to analyze the complexity of translating novel molecular entities and nanomaterials into pharmaceutical alternatives (i.e., knowledge translation, KT) is discussed. First, some key concepts on the organization and translation of the biomedical knowledge (paradigms, homophily, power law distributions, hierarchy, modularity, and ...
arxiv +1 more source
Treatment of Marburg and Ebola hemorrhagic fevers: A strategy for testing new drugs and vaccines under outbreak conditions. [PDF]
The filoviruses, Marburg and Ebola, have the dubious distinction of being associated with some of the highest case-fatality rates of any known infectious disease-approaching 90% in many outbreaks.
A.G. Sprecher+105 more
core +2 more sources
Ebola Hemorrhagic Fever as a Public Health Emergency of International Concern; a Review Article
Ebola hemorrhagic fever (EHF) was first reported in 1976 with two concurrent outbreaks of acute viral hemorrhagic fever centered in Yambuku (near the Ebola River), Democratic Republic of Congo, and also in Nzara, Sudan.
Saeed Safari+4 more
doaj +1 more source
Viewpoint: filovirus haemorrhagic fever outbreaks: much ado about nothing? [PDF]
The recent outbreak of Marburg haemorrhagic fever in the Democratic Republic of Congo has put the filovirus threat back on the international health agenda.
Boelaert, M+7 more
core +3 more sources
Awareness of Ebola Virus Disease among the Medical and Non-medical Personnel in Lahore
Background: Ebola hemorrhagic fever, also called Ebola Virus Disease (EVD), is caused by a member of Filoviridae family known as Ebola Virus (EBOV).
Waqas Iftikhar+5 more
doaj +1 more source
Mapping of Ebola virus spillover: Suitability and seasonal variability at the landscape scale [PDF]
The unexpected Ebola virus outbreak in West Africa in 2014 involving the Zaire ebolavirus made clear that other regions outside Central Africa, its previously documented niche, were at risk of future epidemics. The complex transmission cycle and a lack of epidemiological data make mapping areas at risk of the disease challenging.
arxiv +1 more source
Factors Associated with Marburg Hemorrhagic Fever: [PDF]
Background. Reliable on-site polymerase chain reaction (PCR) testing for Marburg hemorrhagic fever (MHF) is not always available. Therefore, clinicians triage patients on the basis of presenting symptoms and contact history.
Bengi Moco Henrique+12 more
core +2 more sources
Ebola Virus Hemorrhagic Fever [PDF]
This past year has seen the largest Ebola virus outbreak on record, centered in West Africa in Guinea, Liberia, and Sierra Leone. 1 Cases were first reported in Guinea on March 21, 2014; by March 30, cases were reported in Liberia and in May Sierra Leone also reported cases.
openaire +2 more sources
Perspectives on West Africa Ebola Virus Disease Outbreak, 2013–2016
The variety of factors that contributed to the initial undetected spread of Ebola virus disease in West Africa during 2013–2016 and the difficulty controlling the outbreak once the etiology was identified highlight priorities for disease prevention ...
Jessica R. Spengler+4 more
doaj +1 more source