Projections of Ebola outbreak size and duration with and without vaccine use in Équateur, Democratic Republic of Congo, as of May 27, 2018. [PDF]
, 2018 As of May 27, 2018, 6 suspected, 13 probable and 35 confirmed cases of Ebola virus disease (EVD) had been reported in Équateur Province, Democratic Republic of Congo. We used reported case counts and time series from prior outbreaks to estimate the total
Ackley, Sarah +17 more
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Ebolavirus Vaccines: Progress in the Fight Against Ebola Virus Disease
Cellular Physiology and Biochemistry, 2015 Ebolaviruses are highly infectious pathogens that cause lethal Ebola virus disease (EVD) in humans and non-human primates (NHPs). Due to their high pathogenicity and transmissibility, as well as the potential to be misused as a bioterrorism agent ...
Xiao-Xin Wu +8 more
doaj +1 more source
Modernising epidemic science: enabling patient-centred research during epidemics [PDF]
, 2016 Background: Emerging and epidemic infectious disease outbreaks are a significant public health problem and global health security threat. As an outbreak begins, epidemiological investigations and traditional public health responses are generally mounted ...
Horby, Peter W., Rojek, Amanda M.
core +3 more sources
The Final (Oral Ebola) Vaccine Trial on Captive Chimpanzees? [PDF]
, 2017 Could new oral vaccine technologies protect endangered wildlife against a rising tide of infectious disease? We used captive chimpanzees to test oral delivery of a rabies virus (RABV) vectored vaccine against Ebola virus (EBOV), a major threat to wild ...
Goetzmann, Jason E. +5 more
core +2 more sources
Human Vaccines & Immunotherapeutics, 2021 Clinical development of Ebola virus vaccines (EVV) was accelerated by the West African Ebola virus epidemic which remains the deadliest in history. To compare and rank the EVV according to their immunogenicity and safety.
Alhassane Diallo +7 more
doaj +1 more source
The Social and Political Dimensions of the Ebola Response: Global Inequality, Climate Change, and Infectious Disease [PDF]
, 2016 The 2014 Ebola crisis has highlighted public-health vulnerabilities in Liberia, Sierra Leone, and Guinea – countries ravaged by extreme poverty, deforestation and mining-related disruption of livelihoods and ecosystems, and bloody civil wars in the ...
A Kay +41 more
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Current State of the Development of Next-Generation Vaccines against Ebola Virus Disease
Проблемы особо опасных инфекций, 2015 Representative of Ebolavirus gender, Filoviridae family, Ebola virus is an etiological agent of particularly dangerous viral fever, the lethality of which comes up to 88 %.
T. E. Sizikova +4 more
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Ebola and Marburg virus vaccines [PDF]
Virus Genes, 2017 The filoviruses, Ebola virus (EBOV), and Marburg virus (MARV), are among the most pathogenic viruses known to man and the causative agents of viral hemorrhagic fever outbreaks in Africa with case fatality rates of up to 90%. Nearly 30,000 infections were observed in the latest EBOV epidemic in West Africa; previous outbreaks were much smaller ...
Reynolds, Pierce, Marzi, Andrea
openaire +2 more sources
Organisation of Health Care During an Outbreak of Marburg Haemorrhagic Fever in the Democratic Republic of Congo, 1999. [PDF]
, 2004 Organising health care was one of the tasks of the International Scientific and Technical Committee during the 1998-1999 outbreak in Durba/Watsa, in the north-eastern province (Province Orientale), Democratic Republic of Congo.
Borchert, M +10 more
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Data Fitting and Scenario Analysis of Vaccination in the 2014 Ebola Outbreak in Liberia [PDF]
Osong Public Health and Research Perspectives, 2019 Objectives This study aimed to extend an epidemiological model (SEIHFR) to analyze epidemic trends, and evaluate intervention efficacy. Methods SEIHFR was modified to examine disease transmission dynamics after vaccination for the Ebola outbreak.
Zhifu Xie
doaj +1 more source