Results 101 to 110 of about 1,763,176 (361)

Integrating Affinity Chromatography in the Platform Process for Adenovirus Purification

Biotechnology and Bioengineering, EarlyView.
Peptide‐functionalized affinity resins with high adenovirus binding capacity, recovery, and contaminant removal afford excellent productivity, and reduced impurities in a three‐step purification process. ABSTRACT Adenoviral vectors (AdVs) are gaining prominence in cancer therapy and vaccine development, posing the need for a modern AdV manufacturing ...
Yuxuan Wu, Eduardo Barbieri, William K. Smith, Arianna Minzoni, Ryan E. Kilgore, Wenning Chu, Michael A. Daniele, Stefano Menegatti   +7 more
wiley   +1 more source

A genome-wide CRISPR screen identifies N-acetylglucosamine-1-phosphate transferase as a potential antiviral target for Ebola virus

Nature Communications, 2019
There are no approved therapies for Ebola virus infection. Here, to find potential therapeutic targets, we perform a screen for genes essential for Ebola virus (EBOV) infection.
M. Flint, P. Chatterjee, D. L. Lin, L. McMullan, P. Shrivastava-Ranjan, É. Bergeron, Michael K. Lo, S. R. Welch, S. Nichol, Andrew W. Tai, C. Spiropoulou   +10 more
semanticscholar   +1 more source

Ebola Virus Diseases

African Journal of Clinical and Experimental Microbiology, 2014
Since the first reported outbreak of Ebola in 1976, there have been approximately 25 outbreaks all of which, except two, have been reported only in east and central Africa. The current outbreak and a single case reported in 1994 in Ivory Coast are the only two outbreaks in West Africa (7).
A Elisha, B Adegboro
openaire   +4 more sources

Ebola and Marburg virus vaccines [PDF]

Virus Genes, 2017
The filoviruses, Ebola virus (EBOV), and Marburg virus (MARV), are among the most pathogenic viruses known to man and the causative agents of viral hemorrhagic fever outbreaks in Africa with case fatality rates of up to 90%. Nearly 30,000 infections were observed in the latest EBOV epidemic in West Africa; previous outbreaks were much smaller ...
Pierce Reynolds, Andrea Marzi
openaire   +3 more sources

COP27 Climate Change Conference: Urgent action needed for Africa and the world

, 2022
Australian Journal of Rural Health, Volume 30, Issue 6, Page 836-838, December 2022.
Lukoye Atwoli, Gregory E. Erhabor, Aiah A. Gbakima, Abraham Haileamlak, Jean‐Marie Kayembe Ntumba, James Kigera, Laurie Laybourn‐Langton, Bob Mash, Joy Muhia, Fhumulani Mavis Mulaudzi, David Ofori‐Adjei, Friday Okonofua, Arash Rashidian, Maha El‐Adawy, Siaka Sidibé, Abdelmadjid Snouber, James Tumwine, Mohammad Sahar Yassien, Paul Yonga, Lilia Zakhama, Chris Zielinski   +20 more
wiley   +1 more source

Infrastructural state capacity in the digital age: What drives the performance of COVID‐19 tracing apps?

Governance, Volume 36, Issue 1, Page 275-297, January 2023., 2023
Abstract In a context where states increasingly complement their physical presence with digital means, the classic idea of infrastructural state power needs reconsideration. The COVID‐19 pandemic represents an unparalleled opportunity to that end, given the uniformity of one type of digital infrastructural intervention—the offer of contact tracing apps‐
Luciana Cingolani
wiley   +1 more source

Elucidating variations in the nucleotide sequence of Ebola virus associated with increasing pathogenicity [PDF]

, 2014
Background Ebolaviruses cause a severe and often fatal haemorrhagic fever in humans, with some species such as Ebola virus having case fatality rates approaching 90%. Currently, the worst Ebola virus outbreak since the disease was discovered is occurring
A Groseth, A Pichlmair, A Sanchez, A Topfer, AA Chepurnov, B Hudjetz, BM Connolly, C Trapnell, Christiane Hertz-Fowler, Cyril Empig, D Falzarano, David A Matthews, E Adu-Gyamfi, E Ryabchikova, E Subbotina, EM Leroy, ET Bowen, F Feldmann, G Gabriel, G Liu, GA Marsh, GS Mohan, H Ebihara, HM Weingartl, I Garcia-Dorival, Irene Taylor, Isabel García-Dorival, John Kenny, John N Barr, JR Kugelman, Julian A Hiscox, Kara Corbin-Lickfett, KM Johnson, Kyle Schlunegger, LJ Reed, LR Baden, M Linster, M Martin, M Mateo, M Mehedi, M Mehedi, MA Larkin, Miles W Carroll, N Biedenkopf, N van Doremalen, NA Twenhafel, Neil Hall, O Martinez, Roger Hewson, S Baize, S Herfst, S Pattyn, SA Carroll, SP Reid, Stuart D Dowall, T Hoenen, VA Volchkova, VE Volchkov, VE Volchkov, W Xu, WHO   +60 more
core   +1 more source

Scalable Bayesian divergence time estimation with ratio transformations [PDF]

arXiv, 2021
Divergence time estimation is crucial to provide temporal signals for dating biologically important events, from species divergence to viral transmissions in space and time. With the advent of high-throughput sequencing, recent Bayesian phylogenetic studies have analyzed hundreds to thousands of sequences. Such large-scale analyses challenge divergence
arxiv  

An overview of Ebola virus disease

Northern Clinics of Istanbul, 2016
(Uploaded by Plazi for the Bat Literature Project) Ebola virus disease (EVD), formerly known as Ebola hemorrhagic fever, is a severe, often fatal illness in humans. Ebola virus (EBOV) is transmitted through contact with blood or body fluids of a person who contracted or died from EVD, contaminated objects like needles and infected animals or bush meat.
Gül Karagöz, Ayten Kadanali
openaire   +3 more sources

Process intensification of the baculovirus expression vector system using a perfusion process with a low multiplicity of infection at high cell concentrations

Biotechnology Progress, EarlyView.
Abstract The emergence of new viruses and the spread of existing pathogens necessitate efficient vaccine production methods. The baculovirus expression vector system (BEVS) is an efficient and scalable system for subunit and virus‐like particle vaccine production and gene therapy vectors.
Jort J. Altenburg, Brenda E. Juarez‐Garza, Jelle van Keimpema, Linda van Oosten, Gorben P. Pijlman, Monique M. van Oers, René H. Wijffels, Dirk E. Martens   +7 more
wiley   +1 more source