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Ebola virus disease (EVD) is a severe and frequently lethal disease caused by Ebola virus (EBOV). EVD outbreaks typically start from a single case of probable zoonotic transmission, followed by human-to-human transmission via direct contact or contact ...
Shevin T. Jacob+10 more
semanticscholar +7 more sources
Ebola Virus Transmission Initiated by Systemic Ebola Virus Disease Relapse [PDF]
Summary During the 2018-2020 Nord Kivu Ebola virus disease (EVD) outbreak in the Democratic Republic of the Congo, an individual who had received the Merck rVSV-ZEBOV vaccine was diagnosed with EVD.
Placide Mbala-Kingebeni+49 more
semanticscholar +6 more sources
Ebolaviruses are pathogenic agents associated with a severe, potentially fatal, systemic disease in man and great apes. Four species of ebolaviruses have been identified in west or equatorial Africa. Once the more virulent forms enter the human population, transmission occurs primarily through contact with infected body fluids and can result in major ...
Denis Malvy+4 more
semanticscholar +3 more sources
Understanding Ebola Virus Transmission [PDF]
An unprecedented number of Ebola virus infections among healthcare workers and patients have raised questions about our understanding of Ebola virus transmission.
Seth Judson+2 more
doaj +3 more sources
Postmortem Stability of Ebola Virus
The ongoing Ebola virus outbreak in West Africa has highlighted questions regarding stability of the virus and detection of RNA from corpses. We used Ebola virus–infected macaques to model humans who died of Ebola virus disease. Viable virus was isolated
Joseph B. Prescott+5 more
doaj +3 more sources
EBOLA VIRUS AND EBOLA VIRUS DISEASES
The name of the Ebola virus which is making theheadlines today originates from the Ebola Riverin the Congo. The first time the disease appearedwas in August 1976. Patient zero was aschoolteacher who had been touring along theEbola River just days before he was identifiedwith what become known as the Ebola virus.This was the beginning of ebola viral ...
Alamzeb, Aziz Ahmad, Taj Muhammad Khan
openalex +4 more sources
Ebola virus disease (Ebola hemorrhagic fever) first appeared in 1976 with two concurrent outbreaks of acute viral hemorrhagic fever involving 284 cases (151 deaths [53%]) centred in Nzara, Sudan (1), and 318 cases (280 deaths [88%]) in Yambuku (near the Ebola River), Democratic Republic of Congo (2).
Laupland, Kevin B., Valiquette, Louis
openaire +9 more sources
Ebola Virus Disease Vaccines: Development, Current Perspectives & Challenges
The global outgoing outbreaks of Ebola virus disease (EVD) in different regions of Sudan, Uganda, and Western Africa have brought into focus the inadequacies and restrictions of pre-designed vaccines for use in the battle against EVD, which has affirmed ...
S. Malik+11 more
semanticscholar +1 more source
Structure of the Ebola virus polymerase complex
Filoviruses, including Ebola virus, pose an increasing threat to the public health. Although two therapeutic monoclonal antibodies have been approved to treat the Ebola virus disease 1 , 2 , there are no approved broadly reactive drugs to control diverse
Bin Yuan+7 more
semanticscholar +1 more source