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Structure of the Ebola virus polymerase complex
Filoviruses, including Ebola virus, pose an increasing threat to the public health. Although two therapeutic monoclonal antibodies have been approved to treat the Ebola virus disease 1 , 2 , there are no approved broadly reactive drugs to control diverse
Bin Yuan+7 more
semanticscholar +1 more source
Nurses are the largest group of health care providers and, therefore, are often at the forefront of epidemics: responding, treating, educating, and coordinating care as needed. But what happens when nurses are afraid of contracting an illness and decide to leave the workplace?
Nadia Laverne, Etienne+2 more
+8 more sources
Mapping of Ebola virus spillover: Suitability and seasonal variability at the landscape scale [PDF]
The unexpected Ebola virus outbreak in West Africa in 2014 involving the Zaire ebolavirus made clear that other regions outside Central Africa, its previously documented niche, were at risk of future epidemics. The complex transmission cycle and a lack of epidemiological data make mapping areas at risk of the disease challenging.
arxiv +1 more source
Current state of Ebola virus vaccines: A snapshot
Why are Ebola virus vaccines needed? Four species of the genus Ebolavirus cause severe and often lethal disease in humans: Sudan ebolavirus (SUDV), Bundibugyo ebolavirus (BDBV), Taï Forest ebolavirus (TAFV), and Zaire ebolavirus (EBOV) [1]. Historically,
Courtney Woolsey, T. Geisbert
semanticscholar +1 more source
Ebola is a highly pathogenic virus, which in humans reaches a mortality rate above 50%. Due to a lack of laboratories in territories where Ebola viruses are endemic and the limited number of surveillance programmes, tests for the confirmation of suspected cases of Ebola are often performed in Reference Laboratories.
Bettini, Aurora+2 more
openaire +3 more sources
Introduction The Ebola virus disease (EVD) outbreak in 2014–2016 in West Africa was the largest on record and provided an opportunity for large clinical trials and accelerated efforts to develop an effective and safe preventative vaccine.
Moses Badio+25 more
doaj +1 more source
COVID‐19 and myasthenia gravis: A review of neurological implications of the SARS‐COV‐2
Abstract Introduction This review highlights the potential mechanisms of neuromuscular manifestation of COVID‐19, especially myasthenia gravis (MG). Methods An extensive literature search was conducted by two independent investigators using PubMed/MEDLINE and Google Scholar from its inception to December 2020. Results Exacerbations of clinical symptoms
Syed Muhammad Ismail Shah+10 more
wiley +1 more source
Background Following the West Africa Ebola virus disease (EVD) outbreak (2013–2016), WHO developed a preparedness checklist for its member states. This checklist is currently being applied for the first time on a large and systematic scale to prepare for
Olushayo Oluseun Olu+11 more
doaj +1 more source
Ebola Virus Transmission Initiated by Systemic Ebola Virus Disease Relapse
Summary During the 2018-2020 Nord Kivu Ebola virus disease (EVD) outbreak in the Democratic Republic of the Congo, an individual who had received the Merck rVSV-ZEBOV vaccine was diagnosed with EVD.
Placide Mbala-Kingebeni+49 more
semanticscholar +1 more source
Ebola virus disease (EVD) has mostly affected economically deprived countries as limited resources adversely affect a country's infrastructure and administration. Probing into the factors that led to the widespread outbreak, setting forth plans to counter EVD cases in developing countries, and devising definitive measures to limit the spread of the ...
Haider Ghazanfar+3 more
openaire +3 more sources