Results 121 to 130 of about 12,943 (270)
Structural Basis for Differential Neutralization of Ebolaviruses
There are five antigenically distinct ebolaviruses that cause hemorrhagic fever in humans or non-human primates (Ebola virus, Sudan virus, Reston virus, Taï Forest virus, and Bundibugyo virus).
John M. Dye+11 more
doaj +1 more source
The figure shows the effects (increasing upward arrow or decreasing downward arrow) the most common host traits, landscape attributes, climatic features and anthropogenic variables recorded in the review had on the infection and transmission of directly transmitted virus to mammals.
María del Carmen Villalobos‐Segura+3 more
wiley +1 more source
In dieser Studie wurden durch Elektrospinning photoaktive Membranen aus hydrophobem PCL und hydrophilem PAN hergestellt, in die entweder ein hydrophober oder hydrophiler Photosensibilisator eingebettet wurde. Mit Hilfe der Fluoreszenzlebensdauer‐Mikroskopie konnten photoangeregte „aktive Zentren“ innerhalb der Membranen identifiziert werden und damit ...
Fabian Terlau+2 more
wiley +1 more source
Regioselective Deacetylation in Nucleosides and Derivatives
Selective deprotection of the acetyl group(s) in acetylated nucleosides demonstrates practical significance in synthetic processes. It simplifies the preparation of partially or differentially substituted nucleoside intermediates. In this mini‐review, we summarized and evaluated recent approaches for regioselective deacetylation in acetylated ...
Charis Grabbe, Li Cai
wiley +1 more source
Characterization of Influenza Virus Pseudotyped with Ebolavirus Glycoprotein [PDF]
ABSTRACT We have produced a new Ebola virus pseudotype, E-S-FLU, that can be handled in biosafety level 1/2 containment for laboratory analysis. The E-S-FLU virus is a single-cycle influenza virus coated with Ebolavirus glycoprotein, and it encodes enhanced green fluorescence protein as a reporter that replaces the influenza ...
Wim Annaert+6 more
openaire +3 more sources
Novel functional hepatitis C virus glycoprotein isolates identified using an optimised viral pseudotype entry assay [PDF]
Retrovirus pseudotypes are a highly tractable model used to study the entry pathways of enveloped viruses. This model has been extensively applied to the study of the hepatitis C virus (HCV) entry pathway, pre-clinical screening of antiviral antibodies ...
Alexander W. Tarr+7 more
core +1 more source
Advancing the field of viroporins—Structure, function and pharmacology: IUPHAR Review 39
Viroporins possess important potential as antiviral targets due to their critical roles during virus life cycles, spanning from virus entry to egress. Although the antiviral amantadine targets the M2 viroporin of influenza A virus, successful progression of other viroporin inhibitors into clinical use remains challenging.
Kira Devantier+4 more
wiley +1 more source
Ebolavirus and evidence-based speculations.
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Focosi, Daniele+2 more
openaire +4 more sources
A Bayesian analysis of birth pulse effects on the probability of detecting Ebola virus in fruit bats
Since 1976 various species of Ebolavirus have caused a series of zoonotic outbreaks and public health crises in Africa. Bats have long been hypothesised to function as important hosts for ebolavirus maintenance, however the transmission ecology for these
Pleydell, David R.J.+6 more
doaj +1 more source
Sequence determination of complete or coding-complete genomes of viruses is becoming common practice for supporting the work of epidemiologists, ecologists, virologists, and taxonomists.
Jens H. Kuhn+75 more
doaj +1 more source