Results 121 to 130 of about 12,455 (266)

Characterization of Influenza Virus Pseudotyped with Ebolavirus Glycoprotein [PDF]

open access: yesJournal of Virology, 2018
ABSTRACT We have produced a new Ebola virus pseudotype, E-S-FLU, that can be handled in biosafety level 1/2 containment for laboratory analysis. The E-S-FLU virus is a single-cycle influenza virus coated with Ebolavirus glycoprotein, and it encodes enhanced green fluorescence protein as a reporter that replaces the influenza ...
Wim Annaert   +6 more
openaire   +3 more sources

Data Fitting and Scenario Analysis of Vaccination in the 2014 Ebola Outbreak in Liberia [PDF]

open access: yesOsong Public Health and Research Perspectives, 2019
Objectives This study aimed to extend an epidemiological model (SEIHFR) to analyze epidemic trends, and evaluate intervention efficacy. Methods SEIHFR was modified to examine disease transmission dynamics after vaccination for the Ebola outbreak.
Zhifu Xie
doaj   +1 more source

Ebola Virus Disease – An Update [PDF]

open access: yes, 2014
Ebola Virus Disease (EVD) is a severe, haemorrhagic febrile disease, often fatal in humans, caused by a non segmented, negative sense RNA virus of the family Filoviridae and genus Ebolavirus. It is also known as Ebola Haemorrhagic fever.
Kishore, Surekha, Singh, Richa
core   +1 more source

Ebolavirus and evidence-based speculations.

open access: yesThe new microbiologica, 2016
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Focosi, Daniele   +2 more
openaire   +4 more sources

A Bayesian analysis of birth pulse effects on the probability of detecting Ebola virus in fruit bats

open access: yesPeer Community Journal
Since 1976 various species of Ebolavirus have caused a series of zoonotic outbreaks and public health crises in Africa. Bats have long been hypothesised to function as important hosts for ebolavirus maintenance, however the transmission ecology for these
Pleydell, David R.J.   +6 more
doaj   +1 more source

Immunotherapeutics for Ebola Virus Disease: Hope on the Horizon

open access: yesBiologics: Targets & Therapy, 2021
Kyle L O’Donnell, Andrea Marzi Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USACorrespondence: Andrea Marzi Email marzia@niaid.nih ...
O'Donnell KL, Marzi A
doaj  

Standardization of the Filovirus Plaque Assay for Use in Preclinical Studies

open access: yesViruses, 2012
The filovirus plaque assay serves as the assay of choice to measure infectious virus in a cell culture, blood, or homogenized tissue sample. It has been in use for more than 30 years and is the generally accepted assay used to titrate virus in samples ...
Gene G. Olinger   +10 more
doaj   +1 more source

Immunogenicity and safety of Ebola virus vaccines in healthy adults: a systematic review and network meta-analysis

open access: yesHuman Vaccines & Immunotherapeutics, 2021
Clinical development of Ebola virus vaccines (EVV) was accelerated by the West African Ebola virus epidemic which remains the deadliest in history. To compare and rank the EVV according to their immunogenicity and safety.
Alhassane Diallo   +7 more
doaj   +1 more source

YF17D‐based vaccines – standing on the shoulders of a giant

open access: yesEuropean Journal of Immunology, Volume 54, Issue 5, May 2024.
Graphical Abstract: Live‐attenuated yellow fever vaccine (YF17D) has emerged as platform to develop prophylactic and therapeutic vaccines against infectious diseases and cancer. In this review, we summarize the unique polyfunctional immunity endowed by original YF17D, and the progress and challenges of recombinant YF17D‐based vaccines for unmet medical
Lorena Sanchez‐Felipe   +4 more
wiley   +1 more source

Antibody‐dependent enhancement (ADE) of SARS‐CoV‐2 in patients exposed to MERS‐CoV and SARS‐CoV‐2 antigens

open access: yesJournal of Medical Virology, Volume 96, Issue 5, May 2024.
Abstract This study evaluated the potential for antibody‐dependent enhancement (ADE) in serum samples from patients exposed to Middle East respiratory syndrome coronavirus (MERS‐CoV). Furthermore, we evaluated the effect of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) vaccination on ADE in individuals with a MERS infection history.
Swapna Thomas   +12 more
wiley   +1 more source

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