Results 81 to 90 of about 11,522 (197)
Correspondence of Neutralizing Humoral Immunity and CD4 T Cell Responses in Long Recovered Sudan Virus Survivors. [PDF]
, 2016 Robust humoral and cellular immunity are critical for survival in humans during an ebolavirus infection. However, the interplay between these two arms of immunity is poorly understood.
Cose, Stephen +14 more
core +2 more sources
The ebolavirus VP24 interferon antagonist [PDF]
Virulence, 2012 Suppression during the early phases of the immune system often correlates directly with a fatal outcome for the host. The ebolaviruses, some of the most lethal viruses known, appear to cripple initial stages of the host defense network via multiple distinct paths. Two of the eight viral proteins are critical for immunosuppression. One of these proteins
Adrianna P P, Zhang +5 more
openaire +2 more sources
Vox Sanguinis, Volume 120, Issue 8, Page 784-792, August 2025.Abstract Background and Objectives The coronavirus disease 2019 (COVID‐19) pandemic necessitated various therapeutic approaches, including convalescent plasma (CP) administration. The administration timing of COVID‐19 CP (CCP), antibody specificity and quantity were identified as crucial factors for therapeutic success.
Sandra Laner‐Plamberger +9 more
wiley +1 more source
Viruses, 2014 In 2014, Ebola virus (EBOV) was identified as the etiological agent of a large and still expanding outbreak of Ebola virus disease (EVD) in West Africa and a much more confined EVD outbreak in Middle Africa.
Jens H. Kuhn +43 more
doaj +1 more source
Cell Reports, 2021 Summary: The Ebola virus matrix protein VP40 forms distinct structures linked to distinct functions in the virus life cycle. Dimeric VP40 is a structural protein associated with virus assembly, while octameric, ring-shaped VP40 is associated with ...
Sara Landeras-Bueno +8 more
doaj +1 more source
An Interagency Collaboration to Facilitate Development of Filovirus Medical Countermeasures
Viruses, 2012 The Filovirus Animal Non-Clinical Group (FANG) is a US interdepartmental and interagency group established to support and facilitate the advanced development of filovirus Medical Countermeasures (MCM), both vaccines and therapeutics.
Edwin O. Nuzum, Nicole Kilgore
doaj +1 more source
RIG-I activation inhibits ebolavirus replication
Virology, 2009 Hemorrhagic fever viruses are associated with rapidly progressing severe disease with high case fatality, making them of public health and biothreat importance. Effective antivirals are not available for most of the members of this diverse group of viruses. A broad spectrum strategy for antiviral development would be very advantageous. Perhaps the most
Spiropoulou, Christina F. +10 more
openaire +2 more sources
Land Use Change and Infectious Disease Emergence
Reviews of Geophysics, Volume 63, Issue 2, June 2025.Abstract Major infectious diseases threatening human health are transmitted to people from animals or by arthropod vectors such as insects. In recent decades, disease outbreaks have become more common, especially in tropical regions, including new and emerging infections that were previously undetected or unknown. Even though there is growing awareness
M. Cristina Rulli +6 more
wiley +1 more source
Potential Vaccines and Post-Exposure Treatments for Filovirus Infections
Viruses, 2012 Viruses of the family Filoviridae represent significant health risks as emerging infectious diseases as well as potentially engineered biothreats. While many research efforts have been published offering possibilities toward the mitigation of filoviral ...
Gene G. Olinger +6 more
doaj +1 more source
Engineering in Life Sciences, Volume 25, Issue 5, May 2025.ABSTRACT Marburg marburgvirus (MARV) is a highly virulent human pathogen with limited therapeutic options. Recombinant MARV glycoprotein (GP) produced in Drosophila Schneider 2 (S2) cells has been extensively investigated as potential vaccine antigen with promising efficacy demonstrated in nonhuman primate models.
Sven Göbel +7 more
wiley +1 more source