Results 91 to 100 of about 25,220 (171)

Serological evidence of zoonotic filovirus exposure among bushmeat hunters in Guinea

Nature Communications
Human Ebola virus (EBOV) outbreaks caused by persistent EBOV infection raises questions on the role of zoonotic spillover in filovirus epidemiology. To characterise filovirus zoonotic exposure, we collected cross-sectional serum samples from bushmeat ...
Joseph Akoi Boré, Joseph W. S. Timothy, Tom Tipton, Ifono Kekoura, Yper Hall, Grace Hood, Stephanie Longet, Kimberly Fornace, Millimono S. Lucien, Sarah Katarina Fehling, Beatrice K. Koivogui, Si’Ana A. Coggins, Eric D. Laing, Christopher C. Broder, N’ Faly Magassouba, Thomas Strecker, Jeremy Rossman, Kader Konde, Miles W. Carroll   +18 more
doaj   +1 more source

A lethal mice model of recombinant vesicular stomatitis viruses for EBOV-targeting prophylactic vaccines evaluation

Virologica Sinica
• The recombinant VSV-EBOV is highly lethal to IFNα/β/γ R(−/−) mice. • The infected mice exhibit hyperviremia and distinct splenohepatic lesions. • Virus replicon particle vaccine can protect all IFNα/β/γ R(−/−) mice against VSV-EBOV lethal challenge. • This surrogate model can be used for EBOV vaccine evaluation.
Hong-Qing Zhang, Zhe-Rui Zhang, Cheng-Lin Deng, Zhi-Ming Yuan, Bo Zhang   +4 more
openaire   +2 more sources

Neutralising Antibody Activity in Convalescent Plasma of EBOV Survivors [PDF]

, 2023
openaire   +1 more source

A protein-proximity screen reveals Ebola virus co-opts the mRNA decapping complex through the scaffold protein EDC4

Nature Communications
The interaction of host and Ebola virus (EBOV) proteins is required for establishing infection. In this study, we use proximity-dependent biotinylation to identify cellular proteins that bind to EBOV proteins encoded by six of the seven viral genes. Hits
Callie J. Donahue, Aditi S. Kesari, Naveen Thakur, Ling Wang, Sarah Hulsey Stubbs, Caroline G. Williams, Sandhya Bharti Sharma, Cara D. Kirby, Daisy W. Leung, Uma K. Aryal, Christopher F. Basler, Douglas J. LaCount, Robert A. Davey   +12 more
doaj   +1 more source

Bundibugyo virus-perspectives for the current outbreak. [PDF]

Npj Viruses
Hoenen T.
europepmc   +1 more source

Why is there still no licensed vaccine for Bundibugyo ebolavirus? Lessons from the 2026 outbreaks in Uganda and the Democratic Republic of Congo. [PDF]

New Microbes New Infect
Abdi AM, Omar AM, Khalif IA, Adan AM, Bashir SG.   +4 more
europepmc   +1 more source

Machine Learning-Enabled Quantification of Hepatocellular Necrosis in the Liver After Lethal Marburg and Ebola Virus Exposures. [PDF]

J Infect Dis
Liu Y, Chu WT, Gilani SQ, Woodburn DB, Liu DX, Vinithakumari AA, Isic N, Boshinski A, Perry DL, Hischak A, Solomon J, Crozier I, Morris CP.   +12 more
europepmc   +1 more source

2026 Bundibugyo virus outbreak: the role of genomics in <i>Orthoebolavirus</i> outbreaks. [PDF]

Microb Genom
Houldcroft CJ.
europepmc   +1 more source

Comparison of Ebola virus infection routes and resulting disease in animal models. [PDF]

J Virol
Gathright BR, Marzi A.
europepmc   +1 more source

Engineered bispecific antibodies achieve broad and potent protection against multiple ebolavirus species. [PDF]

Emerg Microbes Infect
Zhou J, Zhang B, Yao Y, Li F, Chen S, Wu Y, Xie Y, Guo X, Li W, Peng C, Peng Y, Gao G, Yan F, Gong R, Zhang X, Chiu S.   +15 more
europepmc   +1 more source