Results 81 to 90 of about 28,261 (176)
PLoS Pathogens, 2023 Ebola virus (EBOV) causes severe hemorrhagic fever in humans with high mortality. In Ebola virus disease (EVD) survivors, EBOV persistence in the eyes may break through the inner blood–retinal barrier (iBRB), leading to ocular complications and EVD ...
Jiawang Gao +5 more
doaj
ZNRD2 Mediated Nucleoprotein Aggregation Impairs Respiratory Syncytial Virus Replication
Advanced Science, Volume 13, Issue 12, 27 February 2026.During RSV infection, nucleoprotein (N) forms RNA‐bound oligomers. The host protein ZNRD2 binds to these oligomers, promoting their transition into insoluble aggregates. These aggregates simultaneously sequester functional N to restrict viral production and disrupt chaperonin assembly quality control by interfering with ZNRD2's role as an adaptor ...
Haiwu Zhou +8 more
wiley +1 more source
Frontiers in Microbiology, 2020 Ebola virus (EBOV) has caused several outbreaks as the consequence of spillover events from zoonotic sources and has resulted in huge death tolls. In spite of considerable progress, a thorough know-how regarding EBOV adaptation in various host species ...
Wen Luo +10 more
doaj +1 more source
Advanced Science, Volume 13, Issue 9, 13 February 2026.This study identifies Membralin as an ER‐phagy receptor that recruits MAN1B1 and VCP to form a selective ERLAD complex. By sensing dense N‐glycan clusters on viral fusion glycoproteins, this ubiquitin‐independent pathway directs SARS‐CoV‐2 spike, Ebola GP, influenza HA, and HIV‐1 Env to lysosomal degradation, thereby limiting viral infectivity ...
Jing Zhang +5 more
wiley +1 more source
Purified pAbs from vaccinated TcBs demonstrate neutralizing activity against EBOV and SUDV.
, 2015 Antibodies were purified from plasma collected from both TcBs eight days following the third and fourth vaccinations. (A) These purified V3 (22.16 mg/ml) and V4 (36.68 mg/ml) EBOV/SUDV human pAbs were evaluated by standard ELISA for total IgG antibody ...
John M. Dye (131085) +13 more
core +1 more source
Intra-host Ebola viral adaption during human infection
Biosafety and Health, 2019 The onsite next generation sequencing (NGS) of Ebola virus (EBOV) genomes during the 2013–2016 Ebola epidemic in Western Africa provides an opportunity to trace the origin, transmission, and evolution of this virus.
William J. Liu +32 more
doaj +1 more source
Ebola virus (EBOV) causes Ebola virus disease (EVD), a severe and often fatal hemorrhagic fever. Although much research has focused on host miRNA expression during EBOV infection, it has been discovered that EBOV itself also produces miRNAs.
Christopher Doss +3 more
core +1 more source
EBOV Viability Decay Rates and Half-lives for Each Test Matrix and Environment.
, 2016 A least-squares method was used to calculate the slope of the line defined by the post-drying surface-averaged points for each matrix and environment.
Artemas Herzog (2155816) +9 more
core +1 more source
, 2021 The most advanced vaccines in the US and Europe include Ervebo (rVSV-EBOV), Zabdeno/Mvabea (Ad26-ZEBOV/MVA-BN-Filo), and cAd3-EBOZ (with or without MVA-BN-Filo). These platforms use a viral vector to provoke an immune response, but, as illustrated, there
Thomas W. Geisbert (9239748) +1 more
core +1 more source
Detection of EBOV antibodies, 1976 Democratic Republic of Congo.
, 2018 (A) Representative image of reactive LFn-EBOV-GP and LFn-EBOV-sGP Western blot analysis in 9 sera collected in surrounding areas of the 1976 Ebola virus outbreak in the Democratic Republic of Congo. +, positive control.
Onikepe Folarin (305194) +12 more
core +1 more source