Results 81 to 90 of about 25,220 (171)

Intra-host Ebola viral adaption during human infection

open access: yesBiosafety and Health, 2019
The onsite next generation sequencing (NGS) of Ebola virus (EBOV) genomes during the 2013–2016 Ebola epidemic in Western Africa provides an opportunity to trace the origin, transmission, and evolution of this virus.
William J. Liu   +32 more
doaj   +1 more source

Virus-encoded miRNAs in Ebola virus disease

open access: yesScientific Reports, 2018
Ebola virus (EBOV) is a negative-strand RNA virus that replicates in the cytoplasm and causes an often-fatal hemorrhagic fever. EBOV, like other viruses, can reportedly encode its own microRNAs (miRNAs) to subvert host immune defenses.
Janice Duy   +18 more
doaj   +1 more source

Specific and visual detection of EBOV based on a one-pot RT-RAA-CRISPR/Cas12a assay. [PDF]

open access: yesVirol Sin
Huang Z   +11 more
europepmc   +4 more sources

Modeling Ebola Virus Transmission Using Ferrets

open access: yesmSphere, 2018
Ebola virus (EBOV) has been responsible for sporadic outbreaks in Central Africa since 1976 and has the potential of causing social disruption and public panic as illustrated by the 2013–2016 epidemic in West Africa.
Marc-Antoine de La Vega   +7 more
doaj   +1 more source

Identification and Potential Functions of Ebola Virus-Encoded microRNAs in EBOV-Infected Human ARPE Cells

open access: yesActa Microbiologica Hellenica
Ebola virus (EBOV) causes Ebola virus disease (EVD), a severe hemorrhagic fever that has high case fatality rates (CFR). Although previous Ebola miRNA research has mainly focused on host miRNA expression during infection, it has been shown that the Ebola virus also encodes miRNAs.
Melvin Mensah-Bonsu   +3 more
openaire   +1 more source

Development of a Pentacistronic Ebola Virus Minigenome System

open access: yesViruses
Ebola virus (EBOV) causes severe disease outbreaks in humans with high case fatality rates. EBOV requires adaptation to cause lethal disease in mice by acquiring single mutations in both the nucleoprotein (NP) and VP24 genes. As an attempt to model mouse-
Brady N. Zell   +6 more
doaj   +1 more source

The vesicular stomatitis virus-based Ebola virus vaccine: From concept to clinical trials

open access: yesHuman Vaccines & Immunotherapeutics, 2018
The devastating Ebola virus (EBOV) epidemic in West Africa in 2013–2016 accelerated the progress of several vaccines and antivirals through clinical trials, including the replication-competent vesicular stomatitis virus-based vaccine expressing the EBOV ...
Ellen Suder   +4 more
doaj   +1 more source

2: Laboratory Values From Positive EBOV Patients [PDF]

open access: yesAmerican Journal of Clinical Pathology, 2015
Emily L. Ryan, Charles E. Hill
openaire   +1 more source

Afucosylated anti-EBOV antibody MIL77-3 engages sGP to elicit NK cytotoxicity

open access: yesJournal of Virology
ABSTRACT MIL77-3 is one component of antibody cocktail that is produced in our lab and represents an effective regimen for animals suffering from Zaire Ebolavirus (EBOV) infection. MIL77-3 is engineered to increase its affinity for the FcγRIIIa (CD16a) by deleting the fucose in the framework region ...
Yuting Zhang   +17 more
openaire   +2 more sources

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