Results 61 to 70 of about 28,261 (176)

Carbohydrate‐Based Drug Discovery: Synthetic Strategies and Clinical Applications

open access: yesIsrael Journal of Chemistry, Volume 66, Issue 3, May 2026.
The picture depicts the molecules discussed in the review. On the left side, the general scaffold of sugars is shown. Next to it are four carbohydrate‐based molecules, including remdesivir, islatravir, empagliflozin, and Globo‐H. Remdesivir and islatravir contain a substituted ribose ring attached to a modified nucleobase.
Stephan Scheeff   +2 more
wiley   +1 more source

EBOV GP–specific IFNγ producing T cell responses (IFNγ ELISpot).

open access: yes, 2021
EBOV GP, Ebola virus glycoprotein; ELISpot, enzyme-linked immunospot; IFNγ, interferon gamma. (DOCX)
Zacchaeus Anywaine (3578855)   +22 more
core   +1 more source

Engineering exosomal cargo loading via endogenous molecular pathways: Strategies to enhance therapeutic potential

open access: yesInterdisciplinary Medicine, Volume 4, Issue 3, May 2026.
This review illustrates how scientists engineer exosomes by hijacking the cell's own cargo‐sorting machinery. These strategies efficiently load therapeutic molecules into natural vesicles, creating powerful next‐generation drug delivery systems (Created with BioGDP.com).
Huanrong Zhu   +6 more
wiley   +1 more source

EBOV seroprevalence estimates using different assays in DRC.

open access: yes, 2023
EBOV seroprevalence estimates using different assays in DRC.
Ynke Larivière (16920398)   +14 more
core   +1 more source

Small Molecule Inhibition of Mononegavirales RNA Polymerases

open access: yesJournal of Medical Virology, Volume 98, Issue 5, May 2026.
ABSTRACT The order Mononegavirales includes several non‐segmented negative‐sense RNA viruses that are significant human pathogens, whose transcription and replication depend on multifunctional RNA‐dependent RNA polymerase (L protein). Recent discoveries in cryo‐electron microscopy (cryo‐EM) have elucidated the structures of these polymerases and their ...
Claire R. Cao   +3 more
wiley   +1 more source

Comparison of EBOV and MARV pathophysiology over time.

open access: yes, 2022
EBOV, Ebola virus; MARV, Marburg virus; NHP, nonhuman primate.
Christopher D. Kane (8592750)   +4 more
core   +1 more source

Discovery of Nanosota-EB1 and -EB2 as Novel Nanobody Inhibitors Against Ebola Virus Infection.

open access: yesPLoS Pathogens
The Ebola filovirus (EBOV) poses a serious threat to global health and national security. Nanobodies, a type of single-domain antibody, have demonstrated promising therapeutic potential.
Fan Bu   +13 more
doaj   +1 more source

Generation and Characterization of a Mouse-Adapted Makona Variant of Ebola Virus

open access: yesViruses, 2019
Ebola virus (EBOV) is a zoonotic pathogen that poses a significant threat to public health, causing sporadic yet devastating outbreaks that have the potential to spread worldwide, as demonstrated during the 2013−2016 West African outbreak.
Mable Chan   +7 more
doaj   +1 more source

Cohorts of immature Pteropus bats show interannual variation in Hendra virus serology

open access: yesJournal of Animal Ecology, Volume 95, Issue 3, Page 521-537, March 2026.
Pteropus bat with offspring, photo taken by Manuel Ruiz‐Aravena. Abstract Understanding the drivers of seasonal disease outbreaks remains a fundamental challenge in disease ecology. Periodic outbreaks can be driven by several seasonally varying factors, including pulses of susceptible individuals through births, changes in host behaviour and social ...
Daniel E. Crowley   +24 more
wiley   +1 more source

Determination of neutralising antibody activity in an EBOV GP psVNA.

open access: yes, 2021
EBOV GP, Ebola virus glycoprotein; psVNA, pseudovirion neutralisation assay. (DOCX)
Zacchaeus Anywaine (3578855)   +22 more
core   +1 more source

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