Results 71 to 80 of about 28,261 (176)
EBioMedicineSummary: Background: Ebola virus disease (EVD) survivors experience ocular sequelae including retinal lesions, cataracts, and vision loss. While monoclonal antibodies targeting the Ebola virus glycoprotein (EBOV-GP) have shown promise in improving ...
Ha-Na Lee +17 more
doaj +1 more source
Sex Differences in Response to Viral Vector Vaccines—Implications for Future Vaccine Design
Immunological Reviews, Volume 338, Issue 1, March 2026.ABSTRACT Vaccination represents one of the most impactful public health achievements, preventing 3.5 to 5 million deaths annually according to estimates of the World Health Organization. Yet, recent outbreaks of emerging and reemerging infectious diseases highlight the need for rapid and strategic vaccine development using vaccine platforms ...
Ilka Grewe +2 more
wiley +1 more source
EBOV viral proteins are readily detectable in CD4+ T-cells.
, 2019 (A) Confocal microscopy analysis of EBOV-exposed CD4+ T-cells for colocalization of the late-endosomal marker Rab7 (green), the lysosomal marker, LC3 (yellow) and EBOV antigens (red); nuclei are stained with DAPI (blue). (B) Dual immuno-gold labeling TEM
Mathieu Iampietro (3387881) +11 more
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EBOV sGP increases the infectivity of EBOV-GFP.
, 2021 (A, B, C) HEK293 and Huh7 cells were infected for 1 h with 50–100 FFU EBOV-GFP and cultured for 72 h in the presence of 100 μg/ml (A, C) or the indicated concentration (B) of EBOV sGP or RESTV sGP. An equivalent amount of CP was added as a control.
Andrea Marzi (146489) +3 more
core +1 more source
ChemMedChem, Volume 21, Issue 4, 25 February 2026.Schematic representation depicting the influence of phosphine ligand identity on the biological and physicochemical characteristics of Pt(II) complexes: PTA promotes antileishmanial activity, PPh2(Php–COOH) strengthens antiviral activity, and TCEP enhances fluorescence.
Antonio A. de Oliveira‐Neto +12 more
wiley +1 more source
Sequences of LAMP primers for EBOV.
, 2016 Sequences of LAMP primers for EBOV.
Ayato Takada (18295) +7 more
core +1 more source
Ebola Virus Infection Modelling and Identifiability Problems
Frontiers in Microbiology, 2015 The recent outbreaks of Ebola virus (EBOV) infections have underlined the impact of the virus as a major threat for human health. Due to the high biosafety classification of EBOV (level 4), basic research is very limited.
Van-Kinh eNguyen +4 more
doaj +1 more source
Direct‐to‐Biology: Streamlining the Path From Chemistry to Biology in Drug Discovery
ChemMedChem, Volume 21, Issue 4, 25 February 2026.Crude yet clever: Direct‐to‐biology workflows exploit nanoscale synthesis and plate‐based assays to accelerate hit discovery, save precious intermediates, and rethink early drug discovery. Direct‐to‐biology (D2B) has emerged as a transformative concept in early drug discovery, defined by the direct on‐target screening of crude reaction mixtures without
Ariane F. Hübner, Fabian Barthels
wiley +1 more source
Comparative EBOV Viability Decay Rates and Stability in Dried Human Whole Blood.
, 2016 (A-B) Surface-composite decay plots in dried blood for EBOV/Mak-C05 and EBOV/Yam-May at 22°C/41% RH (A), and 28°C/90% RH (B). Viability values from stainless steel, TyChem QC, polypropylene (for both EBOV variants), and nitrile (for EBOV/Mak-C05 only ...
Artemas Herzog (2155816) +9 more
core +1 more source