Results 111 to 120 of about 3,723 (172)

Halogenated <i>N</i>-Benzylbenzisoselenazolones Efficiently Inhibit <i>Helicobacter pylori</i> Ureolysis <i>In Vitro</i>. [PDF]

open access: yesACS Med Chem Lett
Grabarek M   +5 more
europepmc   +1 more source

Unveiling the antiviral inhibitory activity of ebselen and ebsulfur derivatives on SARS-CoV-2 using machine learning-based QSAR, LB-PaCS-MD, and experimental assay. [PDF]

open access: yesSci Rep
Sinsulpsiri S   +16 more
europepmc   +1 more source
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The pharmacology of ebselen

Agents and Actions, 1991
Ebselen has been demonstrated to be an effective anti-inflammatory agent in a variety of experimental modelsin vivo which differ from classical tests in that the aetiological roles of hydroperoxides and/or lipoxygenase products appear to be greater. Indeed, ebselen exhibits only weak anti-inflammatory activity in the traditional prostaglandin-dominated
M J, Parnham   +4 more
openaire   +2 more sources

Molecular actions of Ebselen—an antiinflammatory antioxidant

General Pharmacology, 1995
1. Ebselen (2-phenyl-1,2-benzisoselenazol-3(2H)-one) is a non-toxic seleno-organic drug with antiinflammatory, antiatherosclerotic and cytoprotective properties. 2. Ebselen and some of its metabolites are effective reductants of hydroperoxides including those arising in biomembranes and lipoproteins. 3.
Tankred Schewe, T Schewe
exaly   +3 more sources

Ebselen effects on MPTP-induced neurotoxicity

Brain Research, 2006
We evaluated the effect of ebselen on human SH-SY5Y dopaminergic neuronal cells and determined whether ebselen, a glutathione peroxidase-mimetic, protected against MPTP-induced dopamine depletion in mice. Ebselen (10-100 microM) inhibited the proliferation of SH-SY5Y cells dose-dependently.
Holly Brown-Borg   +2 more
exaly   +3 more sources

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