Otoprotective effect of the use of antioxidants on noise exposure in experimental studies with rodents - A systematic review with meta-analysis. [PDF]
Novanta GGR +5 more
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Synthesis of Phosphonate Derivatives of Benzisoselenazolones and Their Remarkable Antiureolytic Activity in <i>Helicobacter pylori</i> Cells. [PDF]
Grabarek M +6 more
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Pharmacological advances in <i>Candida auris</i>: emerging antifungal mechanisms and next-generation therapeutic strategies. [PDF]
Hudu SA +4 more
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Halogenated <i>N</i>-Benzylbenzisoselenazolones Efficiently Inhibit <i>Helicobacter pylori</i> Ureolysis <i>In Vitro</i>. [PDF]
Grabarek M +5 more
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Unveiling the antiviral inhibitory activity of ebselen and ebsulfur derivatives on SARS-CoV-2 using machine learning-based QSAR, LB-PaCS-MD, and experimental assay. [PDF]
Sinsulpsiri S +16 more
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Ebselen has been demonstrated to be an effective anti-inflammatory agent in a variety of experimental modelsin vivo which differ from classical tests in that the aetiological roles of hydroperoxides and/or lipoxygenase products appear to be greater. Indeed, ebselen exhibits only weak anti-inflammatory activity in the traditional prostaglandin-dominated
M J, Parnham +4 more
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Molecular actions of Ebselen—an antiinflammatory antioxidant
General Pharmacology, 19951. Ebselen (2-phenyl-1,2-benzisoselenazol-3(2H)-one) is a non-toxic seleno-organic drug with antiinflammatory, antiatherosclerotic and cytoprotective properties. 2. Ebselen and some of its metabolites are effective reductants of hydroperoxides including those arising in biomembranes and lipoproteins. 3.
Tankred Schewe, T Schewe
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Ebselen effects on MPTP-induced neurotoxicity
Brain Research, 2006We evaluated the effect of ebselen on human SH-SY5Y dopaminergic neuronal cells and determined whether ebselen, a glutathione peroxidase-mimetic, protected against MPTP-induced dopamine depletion in mice. Ebselen (10-100 microM) inhibited the proliferation of SH-SY5Y cells dose-dependently.
Holly Brown-Borg +2 more
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