Results 131 to 140 of about 98,704 (296)

Newly identified properties of known pharmaceuticals and myxobacterial small molecules revealed by screening for autophagy modulators

open access: yesThe FEBS Journal, EarlyView.
Autophagy is a cellular degradation process involved in, for example, immune responses to pathogens and neurodegeneration. To identify modulators of autophagy, we developed a microscopy‐based screening assay and identified previously unknown autophagy‐modulating activities in known drugs and natural products from myxobacteria and fungi.
Janine Fichtner   +13 more
wiley   +1 more source

Making sense of TILs: recommendations for morphological assessment of tumour‐infiltrating lymphocytes in gastro‐oesophageal carcinoma

open access: yesHistopathology, EarlyView.
This review examines the role of tumour‐infiltrating lymphocytes (TILs) in gastro‐oesophageal carcinoma (GEC), focusing on their composition, clinical relevance and therapeutic utility. It proposes a framework for standardised evaluation and reporting of TILs, addressing GEC‐specific pathology challenges to support the widespread use and validation of ...
Ylva A Weeda   +38 more
wiley   +1 more source

Immune non‐response despite effective antiretroviral therapy in people living with HIV: A review of potential mechanisms, biomarkers and therapeutic approaches

open access: yesHIV Medicine, EarlyView.
Abstract Introduction A proportion of people living with HIV (PLWH) fail to restore their CD4 count or their CD4/CD8 ratio despite effective antiretroviral therapy (ART). PLWH with immune non‐response (INR) are at a higher risk of both AIDS and non‐AIDS events. The underlying mechanisms of INR remain unclear.
Charlotte Silvestre   +2 more
wiley   +1 more source

In Silico Characterization of Putative Ebv Receptor(S) on Prostate Cells and Repurposing Clinically Approved Drugs as Ebv Entry Inhibitors

open access: green, 2023
Khalid Ahmed   +8 more
openalex   +1 more source

Clinical characteristics of autoimmune glial fibrillary acidic protein astrocytopathy in adults: a retrospective analysis of 9 cases

open access: yesInternal Medicine Journal, EarlyView.
Abstract Background To identify early diagnostic clues, we analysed cerebrospinal fluid and serum biomarkers in patients with autoimmune glial fibrillary acidic protein astrocytopathy (GFAP‐A) and compared biomarker trends with those in patients with viral meningoencephalitis, tuberculous meningoencephalitis, and anti‐N‐methyl‐D‐aspartate receptor ...
Siruo Guo   +3 more
wiley   +1 more source

EBV [PDF]

open access: yes, 2019
openaire   +1 more source

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