Results 121 to 130 of about 112,556 (314)

Juvenile Gangrenous Vasculitis of the Scrotum or Scrotum Lipschütz Ulcers

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Lipschütz genital ulcers are traditionally described in adolescent females and often linked to acute viral infections. Their male counterpart remains poorly characterised. We report a 59‐year‐old man with sudden onset of unilateral necrotic ulcers on the scrotum and inguinal region following a brief febrile episode and mild pharyngitis ...
Francesco Bellinato   +2 more
wiley   +1 more source

Radiotherapy‐Induced Otitis Media With Effusion in Nasopharyngeal Carcinoma: A Meta‐Analysis

open access: yesThe Laryngoscope, EarlyView.
This meta‐analysis of eight studies comprising 582 NPC patients provides the first quantitative synthesis of radiotherapy‐induced otitis media with effusion (OME), demonstrating a significant overall risk difference of 0.18 (95% CI: −0.06 to 0.42, p < 0.0001) in OME naive ears.
Nevin Yi Meng Chua   +3 more
wiley   +1 more source

Transoral Ultrasound in the Diagnostic Workup of Peritonsillar Abscess—A Randomized Clinical Trial

open access: yesThe Laryngoscope, EarlyView.
Peritonsillar abscess frequently mimics peritonsillar cellulitis, exposing many patients to unnecessary and often painful blind needle aspirations. In this multicenter randomized clinical trial of 95 patients, adding transoral ultrasound to standard examination reduced needle aspiration attempts by nearly one third.
Tobias Todsen   +8 more
wiley   +1 more source

EBV-induced mevalonate metabolism supplies geranylgeranyl pyrophosphate (GGPP) for newly infected B-cell outgrowth.

open access: yes, 2019
(A) Fold change in live cell number of primary human B-cells infected by EBV B95-8 for the indicated DPI, cultured in the presence of DMSO or simvastatin (2 μM) from 2–7 DPI. Simvastatin was refreshed at 4 DPI.
Zhonghao Wang (710309)   +9 more
core   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik   +3 more
wiley   +1 more source

Analysis of the variability of Epstein-Barr virus genes in infectious mononucleosis: Investigation of the potential correlation with biochemical parameters of hepatic involvement [PDF]

open access: yesJournal of Medical Biochemistry, 2016
Background: Primary Epstein-Barr virus (EBV) infection is usually asymptomatic, although at times it results in the benign lymphoproliferative disease, infectious mononucleosis (IM), during which almost half of patients develop hepatitis. The aims of the
Banko Ana   +8 more
doaj  

The novel negative checkpoint regulator VISTA is expressed in gastric carcinoma and associated with PD-L1/PD-1: A future perspective for a combined gastric cancer therapy?

open access: yesOncoImmunology, 2017
A combined blockade of V-domain Ig suppressor of T-cell activation (VISTA) and PD-1 is a promising new cancer treatment option, which was efficient in murine tumor models and is currently tested in first phase I studies.
Christine Böger   +3 more
doaj   +1 more source

EBV-DNA load was positively correlated with TAM and vessel density.

open access: yes
(A) and (B)Spearman Rank Correlation Test was used to explore the correlation between EBV-DNA load and TAM/vessel density. * P .05, ** P .01, *** P .001, **** P .0001, NS, not significant. (PDF)
Nannan Zhu (194119)   +7 more
core   +1 more source

EBV-infected lymphoma cells express the PD-L1 and PD-L2 ligands in cord blood-humanized mice.

open access: yes, 2016
A) B cells isolated from pancreatic tissue or spleens of mice injected with EBV-infected cord blood, or mock-treated cord blood, were stained with antibodies specific for human CD45, CD19, CD20, CD3, PD-L1, PD-L2 or isotype matched negative controls and ...
Henri-Jacques Delecluse (166065)   +7 more
core   +1 more source

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