Molecular Functions and Drug Prediction of MMP1 and TGFBR2 in Nasopharyngeal Carcinoma
Journal of Clinical Laboratory Analysis, EarlyView.MMP1 and TGFBR2 were validated by machine learning and external datasets as the candidate genes. Dexamethasone showed strong binding affinity to MMP1 (−7.72 kcal/mol) and TGFBR2 (−7.27 kcal/mol) in docking studies. Knockdown of MMP1 repressed the malignant phenotypes of NPC cells.
Feng Wang +5 more
wiley +1 more source
Role of EBNA-3 Family Proteins in EBV Associated B-cell Lymphomagenesis
Frontiers in Microbiology, 2016 Epstein-Barr virus (EBV) is highly ubiquitous in human population and establishes a lifelong asymptomatic infection within the infected host unless the immune system is compromised.
Shaoni eBhattacharjee +3 more
doaj +1 more source
Expression of the anti-apoptotic bfl-1/A1 gene is regulated by the Epstein Barr virus nuclear antigen 2(EBNA2) [PDF]
, 2003 The ubiquitous and oncogenic human herpesvirus Epstein-Barr virus (EBV) establishes a latent infection and promotes the long-term survival of the infected host cell by targeting the molecular machinery that controls cell fate decisions (apoptosis ...
Pegman, Pamela Mary
core
Aphasic status epilepticus due to Epstein–Barr virus meningoencephalitis – A clinical vignette
Epileptic Disorders, EarlyView.
Gemma Bassani +6 more
wiley +1 more source
Journal of Pediatric Gastroenterology and Nutrition, EarlyView.Abstract Objectives To assess the feasibility and efficacy of fecal microbiota transplantation (FMT) in adolescents (16–21 years) with refractory irritable bowel syndrome (IBS). Methods Randomized controlled pilot trial. Thirty‐two patients were included and randomized to receive two allogeneic or autologous FMTs.
Clara M. A. de Bruijn +8 more
wiley +1 more source
Shared mechanisms in stemness and carcinogenesis: lessons from oncogenic viruses
Frontiers in Cellular and Infection Microbiology, 2013 A rise in technologies for epigenetic reprogramming of cells to pluripotency highlights the potential of understanding and manipulating cellular plasticity in unprecedented ways.
Demetris eIacovides +3 more
doaj +1 more source
Uirusu, 2014 Epstein-Barr virus (EBV) is a member of gamma-herpesvirus, which can cause various types of tumor. Coexisting with the host for a long period of time, it has evolved unique and sophisticated strategy for survival by taking complicated, tactical modes of infection.
openaire +3 more sources
EBV-DNA in peripheral blood of mice inoculated with LCLs.
The EBV copy number in peripheral blood of mice inoculated with LCLs-WT and LCLs-dBNRF1 was quantified by qPCR analysis at the indicated time points. (TIFF)
Hitoshi Kiyoi (4458919) +9 more
core +1 more source
Relationship Between Non-Hodgkin's Lymphoma and Blood Levels of Epstein-Barr Virus in Children in North-Western Tanzania: A Case Control Study. [PDF]
, 2013 Non-Hodgkin's Lymphomas (NHL) are common in African children, with endemic Burkitt's lymphoma (BL) being the most common subtype. While the role of Epstein-Barr Virus (EBV) in endemic BL is known, no data are available about clinical presentations of NHL
Rambau, Peter +30 more
core +1 more source
Hodgkin lymphoma of the ampulla of Vater: A rare cause of obstructive jaundice in children
JPGN Reports, EarlyView.Abstract Hodgkin lymphoma (HL) has a wide spectrum of presentation. Most cases affect lymph nodes (nodal), while extranodal involvement is rare. Whereas the gastrointestinal tract is enriched with lymphoid tissues, the ampulla of Vater is not rich in lymphoid tissue. Involvement of the ampulla of Vater with HL has rarely been reported in adults and has
Sultana Alshammari +12 more
wiley +1 more source