Results 111 to 120 of about 125,177 (307)

EBV-miR-BART1-5P promotes the proliferation of NPC cells.

open access: yes, 2018
(A, C) colony formation assay, (B, D) EdU incorporation assays of NPC cells performed after transfection with NC, anti-c, EBV-miR-BART1-5P mimics, inhibitor and/or PTEN plasmid, si-PTEN as indicated. The data were shown as the mean ± s.e.m.
Jianguo Wang (1400488)   +17 more
core   +1 more source

Enhanced CRISPR‐cas systems for genome editing and molecular diagnostics

open access: yesInterdisciplinary Medicine, EarlyView.
This review systematically summarizes the major optimization strategies for CRISPR‐Cas systems, focusing on the engineering of Cas proteins, guide RNAs, reporter probes, and the incorporation of chemical additives. The aim is to enhance editing precision and diagnostic capability, thereby expanding the CRISPR system's potential for broader biomedical ...
Sheng Li   +7 more
wiley   +1 more source

MECHANISMS OF IMMUNOLOGICAL TOLERANCE DISRUPTION

open access: yesTransactions of the Karelian Research Centre of the Russian Academy of Sciences, 2016
Autoimmune diseases belong to disorders with an unclear etiology. The spectrum of autoimmune diseases is wide, the most well known of them are type 1 diabetes, rheumatoid arthritis, systemic lupus erythematosus, multiple sclerosis, Crohn’s disease ...
Polina Kravchenko, Evgenia Oleinik
doaj   +1 more source

EBV-miR-BART1-5P directly targets cellular AMPKα1 gene.

open access: yes, 2018
(A) EBV-miR-BART1-5P and its putative binding sequences in the 3’UTR of AMPKα1. Mutation was generated in the complementary site that binds to the seed region of BV-miR-BART1-5P.
Jianguo Wang (1400488)   +17 more
core   +1 more source

Pancreas–Intestine Composite Transplantation for Simultaneous Loss of Pancreatic and Intestinal Function (With Video)

open access: yesJournal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Pancreas–intestine composite transplantation (PITx) is a therapeutic option for patients with irreversible loss of both pancreatic and intestinal function. We report a case of PITx in a 16‐year‐old male who developed fulminant Type 1 diabetes mellitus complicated by non‐occlusive mesenteric ischemia, resulting in extensive intestinal necrosis.
Kei Yamane   +24 more
wiley   +1 more source

Epstein–Barr virus and its association with Fascin expression in colorectal cancers in the Syrian population: A tissue microarray study

open access: yesHuman Vaccines & Immunotherapeutics, 2017
Colorectal cancer (CRC) is the third most common malignancy in both men and women worldwide. Colorectal carcinogenesis is a complex, multistep process involving environmental and lifestyle features as well as sequential genetic changes in addition to ...
Noor Al-Antary   +5 more
doaj   +1 more source

MRI‐Derived Lymph Node Characteristics for Risk Stratification of Distant Metastasis in Locoregionally Advanced Nasopharyngeal Carcinoma

open access: yesJournal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background MRI‐derived nodal features may improve prognostication beyond TNM staging, but distant‐metastasis risk models remain limited. Purpose To develop and internally validate an MRI model for distant metastasis prediction in locoregionally advanced nasopharyngeal carcinoma (LA‐NPC). Study Type Retrospective.
Jing Wang   +10 more
wiley   +1 more source

High Level Estradiol Induces EBV Reactivation and EBV gp350/220(+)CD138(+) Double-positive B Cell Population in Graves’ Disease Patients and Healthy Controls [PDF]

open access: yes
Graves’ disease occurs predominantly in women. Epstein-Barr virus (EBV) mainly persists in human B lymphocytes, and its reactivation stimulates antibody production.
90294321   +29 more
core   +1 more source

Heterogeneous effects of donor‐related risk factors in 954 pediatric liver transplantations

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Accepting a suitable donor for a child awaiting pediatric liver transplantation (pLT) is increasingly challenging. Donor‐specific risk factors influence post‐transplant outcomes, but evidence in pediatric patients remains inconsistent.
Christoph Leiskau   +12 more
wiley   +1 more source

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