Results 111 to 120 of about 125,177 (307)
EBV-miR-BART1-5P promotes the proliferation of NPC cells.
(A, C) colony formation assay, (B, D) EdU incorporation assays of NPC cells performed after transfection with NC, anti-c, EBV-miR-BART1-5P mimics, inhibitor and/or PTEN plasmid, si-PTEN as indicated. The data were shown as the mean ± s.e.m.
Jianguo Wang (1400488) +17 more
core +1 more source
Enhanced CRISPR‐cas systems for genome editing and molecular diagnostics
This review systematically summarizes the major optimization strategies for CRISPR‐Cas systems, focusing on the engineering of Cas proteins, guide RNAs, reporter probes, and the incorporation of chemical additives. The aim is to enhance editing precision and diagnostic capability, thereby expanding the CRISPR system's potential for broader biomedical ...
Sheng Li +7 more
wiley +1 more source
MECHANISMS OF IMMUNOLOGICAL TOLERANCE DISRUPTION
Autoimmune diseases belong to disorders with an unclear etiology. The spectrum of autoimmune diseases is wide, the most well known of them are type 1 diabetes, rheumatoid arthritis, systemic lupus erythematosus, multiple sclerosis, Crohn’s disease ...
Polina Kravchenko, Evgenia Oleinik
doaj +1 more source
EBV-miR-BART1-5P directly targets cellular AMPKα1 gene.
(A) EBV-miR-BART1-5P and its putative binding sequences in the 3’UTR of AMPKα1. Mutation was generated in the complementary site that binds to the seed region of BV-miR-BART1-5P.
Jianguo Wang (1400488) +17 more
core +1 more source
ABSTRACT Pancreas–intestine composite transplantation (PITx) is a therapeutic option for patients with irreversible loss of both pancreatic and intestinal function. We report a case of PITx in a 16‐year‐old male who developed fulminant Type 1 diabetes mellitus complicated by non‐occlusive mesenteric ischemia, resulting in extensive intestinal necrosis.
Kei Yamane +24 more
wiley +1 more source
Colorectal cancer (CRC) is the third most common malignancy in both men and women worldwide. Colorectal carcinogenesis is a complex, multistep process involving environmental and lifestyle features as well as sequential genetic changes in addition to ...
Noor Al-Antary +5 more
doaj +1 more source
ABSTRACT Background MRI‐derived nodal features may improve prognostication beyond TNM staging, but distant‐metastasis risk models remain limited. Purpose To develop and internally validate an MRI model for distant metastasis prediction in locoregionally advanced nasopharyngeal carcinoma (LA‐NPC). Study Type Retrospective.
Jing Wang +10 more
wiley +1 more source
High Level Estradiol Induces EBV Reactivation and EBV gp350/220(+)CD138(+) Double-positive B Cell Population in Graves’ Disease Patients and Healthy Controls [PDF]
Graves’ disease occurs predominantly in women. Epstein-Barr virus (EBV) mainly persists in human B lymphocytes, and its reactivation stimulates antibody production.
90294321 +29 more
core +1 more source
Chronic Active Epstein-Barr Virus (EBV) Disease with Haemophagocytic Lymphohistiocytosis and Abnormal T/NK Cells. [PDF]
eJHaem, Volume 7, Issue 6, December 2026.
Al Maashari B +4 more
europepmc +2 more sources
Heterogeneous effects of donor‐related risk factors in 954 pediatric liver transplantations
Abstract Objectives Accepting a suitable donor for a child awaiting pediatric liver transplantation (pLT) is increasingly challenging. Donor‐specific risk factors influence post‐transplant outcomes, but evidence in pediatric patients remains inconsistent.
Christoph Leiskau +12 more
wiley +1 more source

