Results 141 to 150 of about 125,177 (307)

EBV-infected lymphoma cells express the PD-L1 and PD-L2 ligands in cord blood-humanized mice.

open access: yes, 2016
A) B cells isolated from pancreatic tissue or spleens of mice injected with EBV-infected cord blood, or mock-treated cord blood, were stained with antibodies specific for human CD45, CD19, CD20, CD3, PD-L1, PD-L2 or isotype matched negative controls and ...
Henri-Jacques Delecluse (166065)   +7 more
core   +1 more source

Long‐term outcomes of haploidentical hematopoietic stem cell transplantation with antithymocyte globulin–based myeloablative conditioning in pediatric refractory or relapsed non‐Hodgkin lymphoma

open access: yesPediatric Investigation, EarlyView.
Single‐center retrospective data showed that ATG‐based myeloablative haploidentical hematopoietic stem cell transplantation provides durable remission and favorable long‐term survival in children with refractory/relapsed non‐Hodgkin lymphoma, achieving high engraftment rates, low relapse incidence, and acceptable toxicity.
Chenguang Jia   +12 more
wiley   +1 more source

Dynamic early biomarkers predict outcomes in pediatric Epstein–Barr virus‐associated hemophagocytic lymphohistiocytosis

open access: yesPediatric Investigation, EarlyView.
This study elucidates the critical pathogenic mechanisms of pediatric Epstein–Barr virus‐associated hemophagocytic lymphohistiocytosis (EBV‐HLH), where EBV infection triggers a cytokine storm leading to immune cell hyperactivation and tissue damage. Dynamic plasma biomarkers (EBV‐DNA, ferritin, and interferon‐γ) effectively predict treatment response ...
Feifei Liu   +9 more
wiley   +1 more source

Checkmate for EBV-HLH [PDF]

open access: yesBlood, 2020
Kenneth L. McClain   +1 more
openaire   +2 more sources

Suppression of Epstein-Barr virus infection in nasopharyngeal carcinoma cells through CRISPR/Cas9 targeting of EBNA1, OriP and W repeats

open access: yes, 2016
Epstein-Barr virus (EBV) infects more than 90 % of the world's adult population. Persistent infection with EBV is strongly associated with nasopharyngeal carcinoma (NPC), the incidence of which is geographically restricted and particularly high in ...
Jin, D, Yuen, KS, Wong, NHM
core  

Precision immunomodulation for pediatric hemophagocytic lymphohistiocytosis in intensive care

open access: yesPediatric Investigation, EarlyView.
This review presents a bedside framework for recognizing pediatric hemophagocytic lymphohistiocytosis and cytokine storm, stabilizing organ dysfunction, identifying the underlying phenotype, selecting targeted immunomodulation, considering extracorporeal adjuncts, and reassessing response within 24–72 h. ABSTRACT Hemophagocytic lymphohistiocytosis (HLH)
Weerapong Lilitwat, Prakreeti Bhandari
wiley   +1 more source

Endocrine therapy‐induced cancer‐related fatigue in hormone‐dependent malignancies: Mechanisms, impact, and management strategies

open access: yesPrecision Medical Sciences, EarlyView.
Multipathway schematic of endocrine therapy–induced cancer‐related fatigue. Endocrine interventions trigger four interacting mechanisms—neuroendocrine dysregulation, systemic inflammation, energy‐metabolic failure, and psycho‐behavioral amplification—that culminate in the multidimensional CRF phenotype.
Jiajing Jiang   +7 more
wiley   +1 more source

EBV antibodies in SLE patients and healthy controls (%).

open access: yes, 2015
EBV—Epstein-Barr virus, SLE—systemic lupus erythematosus, EBNA-1 –EBV nuclear antigen 1, EBV-VCA—EBV viral capsid antigen, EBV-EA/D—EBV early antigen diffuse, NS—not significant.EBV antibodies in SLE patients and healthy controls (%).
Christoffer T. Nielsen (728072)   +7 more
core   +1 more source

Ruta graveolens L. in Evidence‐Based Phytotherapy: Pharmacological Activities, Bioactive Compounds and Safety

open access: yesPhytotherapy Research, EarlyView.
Graphical representation of ethnomedical uses, major bioactive compounds, pharmacological potential and toxicological risks of Ruta graveolens L. ABSTRACT Ruta graveolens L. is widely used in traditional European, Asian, African, and South American medicine for digestive, nervous, cardiovascular, respiratory, and reproductive disorders.
Tetiana Serhiienko   +3 more
wiley   +1 more source

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