Results 11 to 20 of about 98,704 (296)

Enhancement of specific T-lymphocyte responses by monocyte-derived dendritic cells pulsed with E2 protein of human papillomavirus 16 and human p16INK4A [PDF]

open access: yesPeerJ, 2020
Introduction Prophylactic vaccines are already available for prevention of human papillomavirus (HPV) infection. However, we still await development of therapeutic vaccines with high efficiency for stimulating specific T lymphocytes to clear HPV ...
Nuchsupha Sunthamala   +8 more
doaj   +2 more sources

Inherited immunodeficiencies associated with proximal and distal defects in T cell receptor signaling and co-signaling

open access: yesBiomedical Journal, 2022
T lymphocytes are central cells of adaptive immunity. Activation of T lymphocytes by the antigen receptor of T cells (TCR) and co-stimulatory molecules involve specific signaling components and cascades.
Sylvain Latour
doaj   +1 more source

The interaction between Epstein–Barr virus and multiple sclerosis genetic risk loci: insights into disease pathogenesis and therapeutic opportunities

open access: yesClinical & Translational Immunology, 2023
Multiple sclerosis (MS) is a chronic neurodegenerative autoimmune disease, characterised by the demyelination of neurons in the central nervous system. Whilst it is unclear what precisely leads to MS, it is believed that genetic predisposition combined ...
Ali Afrasiabi   +3 more
doaj   +1 more source

Epstein Barr Virus related cancer in people living with HIV: a review of the literature [PDF]

open access: yesWorld Cancer Research Journal, 2020
The introduction of Highly Active Antiretroviral Therapy (HAART) has modified the natural history of Human Immunodeficiency Virus (HIV) infection, leading to an increase in the life expectancy of the patients living with HIV (PLWH).
F. D’Andrea   +9 more
doaj   +1 more source

EBV and Lymphomagenesis

open access: yesCancers, 2023
The clinical significance of Epstein–Barr virus (EBV) cannot be understated. Not only does it infect approximately 90% of the world’s population, but it is also associated with numerous pathologies. Diseases linked to this virus include hematologic malignancies such as diffuse large B-cell lymphoma, Hodgkin lymphoma, Burkitt lymphoma, primary CNS ...
Sausen, Daniel G.   +2 more
openaire   +2 more sources

Prevalence and association of Epstein-Barr virus infection with sinonasal inverted papilloma and sinonasal squamous cell carcinoma in the northeastern Thai population

open access: yesInfectious Agents and Cancer, 2020
Aims Sinonasal inverted papillomas (SIP) and sinonasal squamous cell carcinomas (SNSCC) are sinonasal tumors with unclear etiology and pathogenesis. Epstein-Barr virus (EBV) has been detected in these tumors but information concerning their association ...
Thawaree Nukpook   +7 more
doaj   +1 more source

EBV CHRONIC INFECTIONS

open access: yesMediterranean Journal of Hematology and Infectious Diseases, 2010
The infection from Epstein-Barr virus (EBV) or virus of infectious mononucleosis, together with other herpesviruses’ infections, represents a prototype of persistent viral infections characterized by the property of the latency. Although the reactivations of the latent infection are associated with the resumption of the viral replication and eventually
PIZZIGALLO, Eligio   +2 more
openaire   +6 more sources

Loss of RASGRP1 in humans impairs T‐cell expansion leading to Epstein‐Barr virus susceptibility

open access: yesEMBO Molecular Medicine, 2018
Inherited CTPS1, CD27, and CD70 deficiencies in humans have revealed key factors of T‐lymphocyte expansion, a critical prerequisite for an efficient immunity to Epstein–Barr virus (EBV) infection.
Sarah Winter   +9 more
doaj   +1 more source

The co-presence of high-risk human papillomaviruses and Epstein-Barr virus is linked with tumor grade and stage in Qatari women with breast cancer

open access: yesHuman Vaccines & Immunotherapeutics, 2021
High-risk human papillomaviruses (HPV) can be present and cooperate with Epstein–Barr virus (EBV) to promote the onset and/or progression of various cancers including cervical, breast, head and neck as well as colorectal.
Ishita Gupta   +7 more
doaj   +1 more source

Active Herpes Virus Infection in Young Children

open access: yesДетские инфекции (Москва), 2018
Under observation were 122 young children (up to 3 years of age), who were identified markers of active forms of herpes virus infections. Markers were studied by PCR in blood, smear from tonsils, saliva, cerebrospinal fluid, urine with determination DNA ...
N. Yu. Egorova   +4 more
doaj   +1 more source

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