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Cancers, 2023 The clinical significance of Epstein–Barr virus (EBV) cannot be understated. Not only does it infect approximately 90% of the world’s population, but it is also associated with numerous pathologies. Diseases linked to this virus include hematologic malignancies such as diffuse large B-cell lymphoma, Hodgkin lymphoma, Burkitt lymphoma, primary CNS ...
Sausen, Daniel G. +2 more
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The Role of NK Cells in EBV Infection and EBV-Associated NPC [PDF]
Viruses, 2021 A vast majority of the population worldwide are asymptomatic carriers of Epstein-Barr Virus (EBV). However, some infected individuals eventually develop EBV-related cancers, including Nasopharyngeal Carcinoma (NPC). NPC is one of the most common EBV-associated epithelial cancers, and is highly prevalent in Southern China and Southeast Asia.
Audrey Zhi Yi Yang +5 more
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Progress in EBV Vaccines [PDF]
Frontiers in Oncology, 2019 The Epstein-Barr virus (EBV) is a ubiquitous pathogen that imparts a significant burden of disease on the human population. EBV is the primary cause of infectious mononucleosis and is etiologically linked to the development of numerous malignancies.
Dwain G. van Zyl +7 more
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Cancers, 2018 Epstein–Barr virus (EBV) infects up to 95% of the adult human population, with primary infection typically occurring during childhood and usually asymptomatic. However, EBV can cause infectious mononucleosis in approximately 35–50% cases when infection occurs during adolescence and early adulthood.
Joseph S. Pagano +2 more
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Uirusu, 2019 Epstein-Barr virus (EBV) is a double stranded DNA virus of the family Herpesviridae. EBV is associated with a variety of lymphomas, and the mechanisms by which it promotes lymphomagenesis have been elucidated; this includes, for example, by translocation/activation of Myc in Burkitt lymphoma.
Hiroshi Kimura, Yusuke Okuno
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Mediterranean Journal of Hematology and Infectious Diseases, 2010 The infection from Epstein-Barr virus (EBV) or virus of infectious mononucleosis, together with other herpesviruses’ infections, represents a prototype of persistent viral infections characterized by the property of the latency. Although the reactivations of the latent infection are associated with the resumption of the viral replication and eventually
PIZZIGALLO, Eligio +2 more
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Mediterranean Journal of Hematology and Infectious Diseases, 2009 Up to 40% of Hodgkin lymphoma (HL) cases are associated with the Epstein-Barr virus (EBV). Clonal viral genomes can be found in the HL tumor cells, the Hodgkin Reed-Sternberg cells (HRS). The latent infection results in expression of the viral oncogenes LMP1 and LMP2A which contribute to generate the particular phenotype of the HRS cells.
Giuseppina Massini +2 more
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Autophagy and immunity – insights from human herpesviruses
Frontiers in Immunology, 2012 The herpesviruses are a family of double-stranded DNA viruses that infect a large variety of organisms. Having co-evolved with their hosts over millennia, herpesviruses have developed a large repertoire of mechanisms to manipulate normal cellular ...
Luke eWilliams, Graham eTaylor
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The Pan African Medical Journal, 2016 INTRODUCTION: in most developing countries, Cytomegalovirus (CMV), Epstein Barr virus (EBV) and Herpes virus 6 (HHV-6) are not diagnosed in blood donors.
Lassina Traore +14 more
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Инфекция и иммунитет, 2022 The role of viral infection in bronchial asthma (BA) is well-known being reflected particularly in GINA. An effect of pneumotropic intracellular persistent herpesviruses on the course of BA is of particular interest. The most common viruses of this group
Evgeniy N. Suprun +5 more
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