Results 51 to 60 of about 218,767 (244)

Analysis of carcinogenic virus infection in HIV-infected patients

Shanghai yufang yixue, 2022
ObjectiveTo investigate the status of carcinogenic infection in people infected with HIV and those with negative HIV test results in VCT clinics. To analyze the epidemiological characteristics and provide scientific basis for more targeted disease ...
ZHANG Yong, XIN Xin, WANG Tao, WU Ping’an, CHEN Jing, LU Yihan   +5 more
doaj   +1 more source

Progress in EBV Vaccines

Frontiers in Oncology, 2019
The Epstein-Barr virus (EBV) is a ubiquitous pathogen that imparts a significant burden of disease on the human population. EBV is the primary cause of infectious mononucleosis and is etiologically linked to the development of numerous malignancies.
Dwain G van Zyl, J. Mautner, H. Delecluse   +2 more
semanticscholar   +1 more source

Epstein-Barr Virus-induced Jaundice [PDF]

, 2020
Infectious mononucleosis is primarily caused by Epstein-Barr virus (EBV) and is a common di-agnosis made in emergency departments worldwide. Subclinical and transient transaminase ele-vations are a well-established sequela of EBV.
Grimaldo, Felipe, Herold, Jessica
core  

The Epstein-Barr Virus Episome Maneuvers between Nuclear Chromatin Compartments during Reactivation. [PDF]

, 2018
The human genome is structurally organized in three-dimensional space to facilitate functional partitioning of transcription. We learned that the latent episome of the human Epstein-Barr virus (EBV) preferentially associates with gene-poor chromosomes ...
Fernandez, Samantha G, McBride, Alison A, Miranda, Jj L, Moquin, Stephanie A, Pollard, Katherine S, Thomas, Sean, Warburton, Alix, Whalen, Sean   +7 more
core   +1 more source

THE RESULTS OF LONG-TERM STUDY OF HERPESVIRUS INFECTION AT THE DEPARTMENT OF INFECTIOUS DISEASES IN CHILDREN OF RUSSIAN NATIONAL RESEARCH MEDICAL UNIVERSITY

Детские инфекции (Москва), 2017
As a result of many years of research, the role of Herpesviridae IV, V and VI types in the structure of various pathologies in children (with infectious mononucleosis (MI), CNS damage, long-term subfebrile syndrome, vasculitis syndrome, hepatitis, etc ...
O. V. Shamsheva, F. S. Kharlamova, N. Yu. Egorova, O. V. Molochkova, E. V. Novosad, E. V. Simonova, T. M. Lebedeva, N. A. Guseva   +7 more
doaj   +1 more source

Human immunity against EBV—lessons from the clinic

Journal of Experimental Medicine, 2017
The mammalian immune system has evolved over many millennia to be best equipped to protect the host from pathogen infection. In many cases, host and pathogen have coevolved, each acquiring sophisticated ways of inducing or protecting from disease ...
S. Tangye, U. Palendira, E. Edwards
semanticscholar   +1 more source

Prediction of haplotypes for ungenotyped animals and its effect on marker-assisted breeding value estimation [PDF]

, 2010
Background: In livestock populations, missing genotypes on a large proportion of animals are a major problem to implement the estimation of marker-assisted breeding values using haplotypes.
Calus, M.P.L., Mulder, H.A., Veerkamp, R.F.   +2 more
core   +3 more sources

The clinical significance of EBV DNA in the plasma and peripheral blood mononuclear cells of patients with or without EBV diseases.

Blood, 2016
Epstein-Barr virus (EBV) is a ubiquitous virus that establishes a latent infection within the host and in some cases can lead to the development of EBV-associated lymphomas, lymphoproliferative disorders, hemophagocytic lymphohistiocytosis, solid tumors,
J. Kanakry, A. Hegde, C. Durand, A. Massie, A. Greer, R. Ambinder, A. Valsamakis   +6 more
semanticscholar   +1 more source

Inactivation of cytidine triphosphate synthase 1 prevents fatal auto-immunity in mice

Nature Communications
De novo synthesis of the pyrimidine, cytidine triphosphate (CTP), is crucial for DNA/RNA metabolism and depends on the CTP synthetases, CTPS1 and −2. Partial CTPS1 deficiency in humans has previously been shown to lead to immunodeficiency, with impaired ...
Claire Soudais, Romane Schaus, Camille Bachelet, Norbert Minet, Sara Mouasni, Cécile Garcin, Caique Lopes Souza, Pierre David, Clara Cousu, Hélène Asnagli, Andrew Parker, Paul Palmquist-Gomes, Fernando E. Sepulveda, Sébastien Storck, Sigolène M. Meilhac, Alain Fischer, Emmanuel Martin, Sylvain Latour   +17 more
doaj   +1 more source

EBV-positive large B-cell lymphomas in young patients: a nodal lymphoma with evidence for a tolerogenic immune environment.

Blood, 2015
Few studies have reported Epstein-Barr virus-positive (EBV(+)) large B-cell lymphomas (LBCLs) in young patients without immunodeficiency. We identified 46 such cases in patients ≤45 years of age and analyzed the clinical and pathological characteristics.
A. Nicolae, S. Pittaluga, Shahed Abdullah, S. Steinberg, T. Pham, T. Davies-Hill, L. Xi, M. Raffeld, E. Jaffe   +8 more
semanticscholar   +1 more source