Results 61 to 70 of about 125,177 (307)
, 2015 EBV expresses a number of viral noncoding RNAs (ncRNAs) during latent infection, many of which have known regulatory functions and can post-transcriptionally regulate viral and/or cellular gene expression. With recent advances in RNA sequencing technologies, the list of identified EBV ncRNAs continues to grow.
Rebecca L, Skalsky, Bryan R, Cullen
openaire +2 more sources
The role of EBV-encoded miRNA in EBV-associated gastric cancer
Frontiers in Oncology, 2023 Epstein-Barr virus ( human herpesvirus 4, EBV) is a linear double-stranded DNA virus that infects over 90% of the population worldwide. However, our understanding of EBV’s contribution to tumorigenesis of EBV-associated GC (EBVaGC) remains incomplete.
Ting Liu +11 more
openaire +3 more sources
Advanced Science, EarlyView.TRIM28 binds to DDX3 protein to catalyze the SUMOylation of DDX3 (S‐DDX3), thus the S‐DDX3 involves in aberrant alternative splicing of KLF4 mRNA, and the splicing variant KLF4α‐mediated cell cycle and signal transduction, weakens tumor suppressor function of DDX3 protein, which promotes progression of HBV‐HCC.
Yanfang Yang +8 more
wiley +1 more source
, 2019 (A) Polyfunctionality profile of latent (responders, KTRs n = 3/5; HCs n = 4/5) and lytic (responders, KTRs n = 8/10; HCs n = 13/15) EBV-specific CD4+ T cells from responding KTRs and HCs, displaying each possible combination of cytokine (IFNγ, IL-2 ...
Sylvain Choquet (7526123) +9 more
core +1 more source
AI‐Driven Cancer Multi‐Omics: A Review From the Data Pipeline Perspective
Advanced Intelligent Discovery, EarlyView.The exponential growth of cancer multi‐omics data brings opportunities and challenges for precision oncology. This review systematically examines AI's role in addressing these challenges, covering generative models, integration architectures, Explainable AI for clinical trust, clinical applications, and key directions for clinical translation.
Shilong Liu, Shunxiang Li, Kun Qian
wiley +1 more source
Epstein Barr Virus Associated B-Cell Lymphomas and Iatrogenic Lymphoproliferative Disorders
Frontiers in Oncology, 2019 Epstein-Barr virus (EBV) is a ubiquitous herpesvirus, affecting up to 90% of the population. EBV was first identified as an oncogenic virus in a Burkitt lymphoma cell line, though subsequently has been found to drive a variety of malignancies, including ...
Jennifer L. Crombie, Ann S. LaCasce
doaj +1 more source
American Journal of Hematology, EarlyView.ABSTRACT Nodal T‐follicular helper cell lymphoma (nTFHL), most commonly of angioimmunoblastic type, exhibits heterogeneous clinical outcomes that are not fully explained by current clinical and biological variables. While genetic alterations have been extensively investigated, its proteomic landscape remains largely unexplored.
David Beauvais +9 more
wiley +1 more source
Medical Journal of BabylonBackground: Herpes viruses like cytomegalovirus (CMV) and Epstein–Barr virus (EBV) can cause serious illness in those who already have impaired immune systems. Objectives: The purpose of this research was to examine the impact of CMV and EBV infection on
Eman Ammar Ihsan +2 more
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Polish Journal of Microbiology, 2022 The infectious agents may be the etiological factor of up to 15–20% of cancers. In stomach cancer, attention is paid to Helicobacter pylori and Epstein-Barr virus, both of which cause gastritis and can lead to tumor development.
Dzikowiec Magdalena +8 more
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Arthritis &Rheumatology, EarlyView.Objective Still disease (SD) is an autoinflammatory disorder characterized by remarkably high interleukin‐18 (IL‐18) levels. Increasing evidence suggests that adaptive immunity also contributes to its pathogenesis, particularly in refractory courses. Macrophage activation syndrome (MAS), one of SD's most severe complications, is associated with further
Greta Rogani +17 more
wiley +1 more source