Results 81 to 90 of about 178,297 (335)

The complexity of dementia development and its comorbidities: The collaborative cross‐mouse population for multivarious tasks approach

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The increasing prevalence of dementia and related neurodegenerative diseases—including Alzheimer's disease, Parkinson's disease, multiple sclerosis, and amyotrophic lateral sclerosis—poses a growing public health challenge. These conditions have traditionally been studied as isolated central nervous system disorders, but emerging evidence points to ...
Osayd Zohud   +3 more
wiley   +1 more source

Associations of Epstein-Barr Virus Infection with Attention Deficit Hyperactivity Disorder, Learning Disability, and Special Education in US Children

open access: yesInternational Journal of General Medicine, 2022
Jingjing Wang,1 Yaping Li,2 Xiaozhen Geng,2 Xin Zhang,2 Yanfeng Xiao,1 Wenjun Wang2 1Department of Pediatrics, Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, People’s Republic of China; 2Department of Infectious Diseases, Second
Wang J   +5 more
doaj  

The Value of Autoantibody and Viral Serologic Examinations in the Differential Diagnosis of Multiple Sclerosis and Stroke

open access: yesTürk Nöroloji Dergisi, 2019
Objective: To evaluate the value of autoantibody and viral serologic examinations in the diagnosis of multiple sclerosis (MS) and stroke and their effect on the course of treatment.
Ahmet, Utku Ogan, Berna, Nefati
doaj   +1 more source

Epstein–Barr Virus, Lower Vitamin D, Low Sun Exposure, and HLA‐DRB1*1501 Risk Variant Share Common Epigenetic Pathways Leading to Multiple Sclerosis Onset

open access: yesAnnals of Neurology, EarlyView.
Objectives Multiple sclerosis (MS) onset risk factors include Epstein–Barr virus (EBV) indices (including host response), lower serum 25‐vitamin D (25(OH)D) levels, low sun exposure, and HLA‐DRB1*1501. The underlying molecular mechanisms are unclear. Here, we examined mediation through differential DNA methylation (DNAm) to better understand possible ...
Steve Simpson‐Yap   +37 more
wiley   +1 more source

Confined B‐Cell Reconstruction and High T‐Cell Clonality Define Clinical Response to Cladribine Treatment

open access: yesAnnals of Neurology, EarlyView.
Cladribine tablets are approved for relapsing multiple sclerosis, mediating their clinical effect by moderately depleting lymphocytes. In a prospective, monocentric study including 22 patients completing 2 annual cycles of cladribine, B‐ and T‐cell receptor repertoires and relapse activity were assessed at baseline and after 24 months. T‐cell clonality
Tilman Schneider‐Hohendorf   +8 more
wiley   +1 more source

Human herpesviruses in the pathogenesis of orbit and eye tumors: detection of herpesvirus DNA in tumor biopsies

open access: yesРоссийский офтальмологический журнал, 2018
Biopsy samples of 32 patients with uveal melanoma (10), RBL (11), orbital lymphoma (7), lacrimal gland adenomas (2), rhabdomyosarcoma of conjunctiva (2) were tested by real time polymerase chain reaction (PCR) to detect the DNA of HSV 1, HSV 2, EBV, CMV,
A. E. Andryushin   +9 more
doaj   +1 more source

Selection of Bali cattle based on birth weight and calving interval records at West Nusa Tenggara Province of Indonesia

open access: yesJournal of the Indonesian Tropical Animal Agriculture, 2020
Birth weight and calving interval are included of productivity traits that can be increased by selection program. However, the standard of desirable birth weight in cattle during the selection program is important to prevent dystocia incident risk.
S. Said   +3 more
doaj   +1 more source

Chimerism after organ transplantation [PDF]

open access: yes, 1997
Recent evidence suggests that passenger leukocytes migrate after organ transplantation and produce persistent chimerism, which is essential for sustained survival of the allograft.
Demetris, AJ   +6 more
core   +1 more source

Serum Cytokine Profiling Differentiates Underlying Diseases in Cytokine Storm Syndrome

open access: yesArthritis &Rheumatology, EarlyView.
Serum cytokine profiling was performed using Luminex (48 cytokines) and ELISA (5 cytokines). Assessment of key cytokines (IFN‐α, IL‐18, IL‐6, CXCL9) delineated five dominant inflammatory patterns: I, IFN‐α–dominant CSS; II, IL‐18–dominant CSS; III, IL‐6–dominant CSS; IV, IFN‐γ–dominant CSS; and V, IL‐6 & IFN‐γ intermediate CSS.
Shuya Kaneko   +42 more
wiley   +1 more source

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