Results 71 to 80 of about 17,129 (220)
Advanced Science, Volume 13, Issue 5, 27 January 2026.Rice gall dwarf virus (RGDV), transmitted biparentally by leafhopper vector to their offspring, exploits the capsid protein to induce inheritable ovarian apoptosis via insulin‐driven PI3K/AKT/FoxO signaling axis. This mechanism enhances infection but reduces female reproductive fitness, causing inefficient maternal transmission.
Haibo Wu +6 more
wiley +1 more source
Developmental Expression of \u3cem\u3eDrop-Dead\u3c/em\u3e is Required for Early Adult Survival and Normal Body Mass in \u3cem\u3eDrosophila melanogaster\u3c/em\u3e [PDF]
, 2012 In Drosophila melanogaster, mutations in the gene drop-dead (drd) result in early adult lethality, with flies dying within 2 weeks of eclosion. Additional phenotypes include neurodegeneration, tracheal defects, starvation, reduced body mass, and female ...
Blumenthal, Edward M +1 more
core +1 more source
TDP-43 loss-of-function causes neuronal loss due to defective steroid receptor-mediated gene program switching in Drosophila [PDF]
, 2013 TDP-43 proteinopathy is strongly implicated in the pathogenesis of amyotrophic lateral sclerosis and related neurodegenerative disorders. Whether TDP-43 neurotoxicity is caused by a novel toxic gain-of-function mechanism of the aggregates or by a loss of
Adachi, Yoshitsugu +13 more
core +3 more sources
Advanced Science, Volume 13, Issue 4, 19 January 2026.This study elucidates a molecular mechanism enabling species coexistence between parasitoid wasps, showing how Asobara japonica uses a set of novel venom proteins to delay host development and exploit older hosts, thereby achieving temporal niche partitioning with Leptopilina drosophilae. Abstract Interspecific competition can drive species coexistence
Junwei Zhang +11 more
wiley +1 more source
MicroRNA expression profiling during the life cycle of the silkworm () [PDF]
, 2009 Background MicroRNAs (miRNAs) are expressed by a wide range of eukaryotic organisms, and function in diverse biological processes. Numerous miRNAs have been identified in Bombyx mori, but the temporal expression profiles of miRNAs corresponding to each ...
Shiping Liu +7 more
core +2 more sources
Ecdysone Oxidase: Reaction and Specificity [PDF]
European Journal of Biochemistry, 1978 Ecdysone oxidase oxidizes 3‐hydroxysteroids of the ecdysteroid type irreversibly to 3‐dehydro derivatives. The hydrogen of the steroid is transferred by the enzyme to oxygen which is reduced to hydrogen peroxide. Ecdysone oxidase is relatively specific for ecdysone and ecdysterone. Apparent Michaelis constants for these two physiological substrates are
J, Koolman, P, Karlson
openaire +2 more sources
Sex‐Specific Response to Predator Auditory Cues in Asian Corn Borer (Ostrinia furnacalis)
Ecology and Evolution, Volume 16, Issue 1, January 2026.Females downregulate more DEGs; males upregulate under predation risk. Males boost ecdysteroid; females reduce fecundity under bat ultrasound. Female O. furnacalis reacted more strongly to auditory cues of bats than males. ABSTRACT Predation risk has profound effects on prey from phenotype to gene expression.
Li Wang +8 more
wiley +1 more source
FEBS Open Bio, 2017 Synthetic nonsteroidal ecdysone agonists, a class of insect growth regulators (IGRs), target the ecdysone receptor (EcR), which forms a heterodimer with ultraspiracle (USP) to transactivate ecdysone response genes.
Sayoko Ito‐Harashima +4 more
doaj +1 more source
Ecdysone signaling induces two phases of cell cycle exit in Drosophila cells
Biology Open, 2016 During development, cell proliferation and differentiation must be tightly coordinated to ensure proper tissue morphogenesis. Because steroid hormones are central regulators of developmental timing, understanding the links between steroid hormone ...
Yongfeng Guo +4 more
doaj +1 more source
Spatiotemporal Crosstalk Between Oocyte and the Microenvironment Governs Preovulatory Follicle Aging
Aging Cell, Volume 25, Issue 1, January 2026.Preovulatory follicle aging is characterized by two distinct phases—early oocyte protective and late degenerative phases. The degenerative phase involves a positive feedback loop between oocyte mitochondrial dysfunction mediated by a mitochondrial‐localized microprotein PIGBOS, and granulosa cell functional decline through a circular RNA circdlg1 ...
Xin Yi Koh +7 more
wiley +1 more source