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Differential control of gene activity by isoforms A, B1 and B2 of the Drosophila ecdysone receptor.

open access: bronze, 2001
Jean‐François Mouillet   +3 more
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Ecdysone Receptors: From the Ashburner Model to Structural Biology [PDF]

open access: possibleAnnual Review of Entomology, 2013
In 1974, Ashburner and colleagues postulated a model to explain the control of the puffing sequence on Drosophila polytene chromosomes initiated by the molting hormone 20-hydroxyecdysone. This model inspired a generation of molecular biologists to clone and characterize elements of the model, thereby providing insights into the control of gene ...
Hill, Ronald J.   +4 more
openaire   +4 more sources
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Heterodimerization of the Drosophila ecdysone receptor with retinoid X receptor and ultraspiracle

Nature, 1993
Ecdysone in Drosophila has been a paradigm for steroid hormones since its ability to induce gene activity directly was demonstrated by its effects on moulting and polytene chromosome puffing. The ecdysone receptor (EcR) was recently confirmed as a member of the nuclear receptor superfamily by cloning and characterization in a Drosophila cell line. Here
H E Thomas   +2 more
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Ecdysone receptors and their biological actions

2000
Publisher Summary This chapter discusses the ecdysone receptors and their biological actions. It also summarizes the insect endocrinology and the roles of these steroids in the molting and metamorphosis. Natural hormones that lead to molting and metamorphosis are ecdysones.
Lynn M. Riddiford   +2 more
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Ligand‐Binding Pocket of the Ecdysone Receptor

2005
The ecdysone receptor (EcR) belongs to the superfamily of nuclear receptors (NRs) that are ligand-dependent transcription factors. Ecdysone receptor is present only in invertebrates and plays a central role in regulating the expression of a vast array of genes during development and reproduction.
Billas, Isabelle,, Moras, Dino
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Nuclear localization and DNA binding of ecdysone receptor and ultraspiracle

Archives of Insect Biochemistry and Physiology, 2007
AbstractThe Ecdysone receptor (EcR) is distributed between cytoplasm and nucleus in CHO cells. Nuclear localization is increased by the ligand Muristerone A. The most important heterodimerization partner Ultraspiracle (Usp) is localized predominantly in the nucleus.
K.‐D. Kröncke   +4 more
openaire   +3 more sources

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