Disease Models & Mechanisms, 2020 Aldosterone is produced by the mammalian adrenal cortex to modulate blood pressure and fluid balance; however, excessive, prolonged aldosterone promotes fibrosis and kidney failure.
Wenjing Zheng, Karen Ocorr, Marc Tatar
doaj +1 more source
Structure of the heterodimeric ecdysone receptor DNA-binding complex [PDF]
The EMBO Journal, 2003 Ecdysteroids initiate molting and metamorphosis in insects via a heterodimeric receptor consisting of the ecdysone receptor (EcR) and ultraspiracle (USP). The EcR-USP heterodimer preferentially mediates transcription through highly degenerate pseudo-palindromic response elements, resembling inverted repeats of 5'-AGGTCA-3' separated by 1 bp (IR-1). The
Srikripa, Devarakonda +4 more
openaire +2 more sources
Genomic Analysis of Drosophila Neuronal Remodeling: A Role for the RNA-Binding Protein Boule as a Negative Regulator of Axon Pruning [PDF]
, 2008 Drosophila mushroom body (MB) {gamma} neurons undergo axon pruning during metamorphosis through a process of localized degeneration of specific axon branches.
Hoopfer, Eric D. +3 more
core +1 more source
Four-way regulation of mosquito yolk protein precursor genes by juvenile hormone-, ecdysone-, nutrient-, and insulin-like peptide signaling pathways. [PDF]
, 2014 Anautogenous mosquito females require a meal of vertebrate blood in order to initiate the production of yolk protein precursors by the fat body. Yolk protein precursor gene expression is tightly repressed in a state-of-arrest before blood meal-related ...
Attardo, Geoffrey M +3 more
core +2 more sources
Pigment dispersing factor regulates ecdysone biosynthesis via bombyx neuropeptide G protein coupled receptor-B2 in the prothoracic glands of Bombyx mori. [PDF]
PLoS ONE, 2014 Ecdysone is the key hormone regulating insect growth and development. Ecdysone synthesis occurs in the prothoracic glands (PGs) and is regulated by several neuropeptides.
Masatoshi Iga +3 more
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A Genetic Mosaic Screen Reveals Ecdysone-Responsive Genes Regulating Drosophila Oogenesis [PDF]
, 2016 Information about the supplemental materials can be found here: www.g3journal.org/lookup/suppl/doi:10.1534/g3.116.028951/-/DC1Multiple aspects of Drosophila oogenesis, including germline stem cell activity, germ cell differentiation, and follicle ...
Ables +15 more
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Effects of methoxyfenozide on ecdysone receptor complex expression in larval Asian gypsy moth
Open Life Sciences, 2015 As a target of insect growth regulators, the ecdysone receptor complex binds ecdysone agonists to regulate gene transcription, development, and growth.
Wu Shao-ping +6 more
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Animal Nutrition, 2022 Cholesterol, as an indispensable nutrient, regulates molting and growth in crustacean. As crustaceans are unable to biosynthesize cholesterol de novo, it is central to understand how dietary cholesterol affects molting in crustaceans.
Tingting Zhu +9 more
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Ash2 acts as an ecdysone receptor coactivator by stabilizing the histone methyltransferase Trr. [PDF]
, 2013 The molting hormone ecdysone triggers chromatin changes via histone modifications that are important for gene regulation. On hormone activation, the ecdysone receptor (EcR) binds to the SET domain-containing histone H3 methyltransferase trithorax-related
Carbonell, Albert +3 more
core +2 more sources
PLoS ONE, 2023 Ecdysteroids control ovary growth and egg production through a complex gene hierarchy. In the female Rhodnius prolixus, a blood-gorging triatomine and the vector of Chagas disease, we have identified the ecdysone response genes in the ovary using ...
Samiha Benrabaa +2 more
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