Juvenile hormone regulates body size and perturbs insulin signaling in Drosophila [PDF]
The role of juvenile hormone (JH) in regulating the timing and nature of insect molts is well-established. Increasing evidence suggests that JH is also involved in regulating final insect size.
Gokhale, R. H. +8 more
core +1 more source
InDrosophila, ecdysone-regulated genes are bound by a heterodimer of ecdysone receptor (EcR) and Ultraspiracle. Here, the authors provide evidence of a non-canonical complex containing EcR and the nucleosome remodeller dMi-2 that limits transcription of ...
Judith Kreher +10 more
doaj +1 more source
Steroid Hormone Signaling Is Essential to Regulate Innate Immune Cells and Fight Bacterial Infection in Drosophila [PDF]
Coupling immunity and development is essential to ensure survival despite changing internal conditions in the organism. Drosophila metamorphosis represents a striking example of drastic and systemic physiological changes that need to be integrated with ...
Brandão, Ana S. +6 more
core +2 more sources
Ecdysone-Related Biomarkers of Toxicity in the Model Organism Chironomus riparius: Stage and Sex-Dependent Variations in Gene Expression Profiles. [PDF]
Despite being considered a model organism in toxicity studies, particularly in assessing the environmental impact of endocrine disrupting compounds (EDCs) and other chemicals, the molecular basis of development is largely unknown in Chironomus riparius ...
Rosario Planelló +5 more
doaj +1 more source
Ecdysone Elicits Chronic Renal Impairment via Mineralocorticoid-Like Pathogenic Activities
Background/Aims: Ecdysteroids are steroidal insect molting hormones that also exist in herbs. Ecdysteroid-containing adaptogens have been popularly used to improve well-being and by bodybuilders for muscle growth.
Minglei Lu +9 more
doaj +1 more source
There is growing evidence that peptides encoded by small open-reading frames (sORF or smORF) can fulfill various cellular functions and define a novel class regulatory molecules.
Azza Dib +11 more
doaj +1 more source
Penaeid shrimp genome provides insights into benthic adaptation and frequent molting [PDF]
Crustacea, the subphylum of Arthropoda which dominates the aquatic environment, is of major importance in ecology and fisheries. Here we report the genome sequence of the Pacific white shrimp Litopenaeus vannamei, covering similar to 1.66 Gb (scaffold ...
Alcivar-Warren, Acacia +32 more
core +3 more sources
Rapid Assessment of Insect Steroid Hormone Entry Into Cultured Cells
Steroid hormones control development and homeostasis in a wide variety of animals by interacting with intracellular nuclear receptors. Recent discoveries in the fruit fly Drosophila melanogaster revealed that insect steroid hormones or ecdysteroids are ...
Mitchell Masterson +5 more
doaj +1 more source
Stage-Specific Plasticity in Ovary Size Is Regulated by Insulin/Insulin-Like Growth Factor and Ecdysone Signaling in Drosophila [PDF]
Animals from flies to humans adjust their development in response to environmental conditions through a series of developmental checkpoints, which alter the sensitivity of organs to environmental perturbation.
Mendes, C. C., Mirth, C. K.
core +2 more sources
Mechanisms of transcriptional regulation of ecdysone response
The mechanisms of ecdysone-dependent expression have been studied for many decades. Initially, the activation of individual genes under the influence of ecdysone was studied on the model of polythene chromosomes from salivary glands of Drosophila ...
M. Yu. Mazina, N. E. Vorobyeva
doaj +1 more source

