Prognostic factors and historical trends in the epidemiology of candidemia in critically ill patients: an analysis of five multicenter studies sequentially conducted over a 9-year period [PDF]
, 2014 To describe temporal trends in the epidemiology, clinical management and outcome of candidemia in intensive care unit (ICU) patients.This study was a retrospective analysis of 1,392 episodes of candidemia in 647 adult ICU patients from 22 Brazilian ...
Andreotti, Ricardo +7 more
core +1 more source
3 Biotech, 2019 Anidulafungin, a new class of antifungal agent used for the treatment of chronic fungal infections, is derived from Echinocandin B nucleus, an intermediate metabolite of Echinocandin B produced by Aspergillus nidulans. The enzyme acylase plays a key role in the bioconversion of Echinocandin B to Echinocandin B nucleus.
J. Savitha +5 more
openaire +3 more sources
Membrane-associated echinocandin B deacylase of Actinoplanes utahensis : purification, characterization, heterologous cloning and enzymatic deacylation reaction [PDF]
, 2000 A J Kreuzman +7 more
openalex +1 more source
Toxicity of LY303366, an Echinocandin Antifungal, in Mice Pretreated with Glucocorticoids [PDF]
, 2000 Karl V. Clemons +2 more
openalex +1 more source
In vitro antifungal activity of FK463, a new water-soluble echinocandin-like lipopeptide [PDF]
, 2000 Hiroshige Mikamo +2 more
openalex +1 more source
Synergy, Pharmacodynamics, and Time-Sequenced Ultrastructural Changes of the Interaction between Nikkomycin Z and the Echinocandin FK463 against Aspergillus fumigatus [PDF]
, 2001 Christine C. Chiou +4 more
openalex +1 more source
mBioRecent epidemiological studies documented an alarming increase in the prevalence of echinocandin-resistant (ECR) Candida glabrata blood isolates. ECR isolates are known to arise from a minor subpopulation of a clonal population, termed echinocandin ...
Amir Arastehfar +8 more
doaj +1 more source
Dosage-Dependent Antifungal Efficacy of V-Echinocandin (LY303366) against Experimental Fluconazole-Resistant Oropharyngeal and Esophageal Candidiasis [PDF]
, 2001 Vidmantas Petraitis +9 more
openalex +1 more source
Tipping the balance both ways: drug resistance and virulence in Candida glabrata [PDF]
, 2017 Among existing fungal pathogens, Candida glabrata is outstanding in its capacity to rapidly develop resistance to currently used antifungal agents. Resistance to the class of azoles, which are still widely used agents, varies in proportion (from 5 to 20%)
Bolotin-Fukuhara, Monique +2 more
core
International Journal of Infectious DiseasesBackground: Echinocandins represent first-line therapy for Candida Bloodstream Infections (C-BSIs). Incidence of treatment failure (TF) remains high with unclear risk factors. Aim: to evaluate predictors of echinocandin TF for C-BSIs.
Davide Fiore Bavaro +27 more
doaj +1 more source