Results 151 to 160 of about 23,261 (287)

Spontaneous Mutational Frequency and FKS Mutation Rates Vary by Echinocandin Agent against Candida glabrata

Antimicrobial Agents and Chemotherapy, 2018
Echinocandins are front-line agents for treatment of invasive candidiasis. There are no reported agent-specific differences in Candida mutational frequency of resistance or propensity to develop FKS mutations. ABSTRACT Echinocandins are front-line agents
R. Shields, Ellen G. Kline, K. Healey, Milena Kordalewska, David S. Perlin, M. Nguyen, C. Clancy   +6 more
semanticscholar   +1 more source

2117. Fluconazole vs. Echinocandins as Initial Therapy for Candidemia Caused by Fluconazole-Susceptible Species in the Era of Rapid Diagnostic Testing [PDF]

, 2019
Danya Roshdy, Tyler Ginn, Rupal K Jaffa, William E. Anderson, Elizabeth Green, Leigh Ann Medaris   +5 more
openalex   +1 more source

Emerging Echinocandin Resistance – A Review

, 2021
P. Sneka, Krishnan Mahalakshmi, V. Sangamithra   +2 more
openalex   +2 more sources

FKS1 mutation associated with decreased echinocandin susceptibility of Aspergillus fumigatus following anidulafungin exposure [PDF]

, 2020
Ana P. Silva, Isabel M. Miranda, Joana Branco, Patrícia Oliveira, Isabel Faria‐Ramos, Raquel M. Silva, Acácio G. Rodrigues, Sofia Costa‐de‐Oliveira   +7 more
openalex   +1 more source

Echinocandin persistence directly impacts the evolution of resistance and survival of the pathogenic fungus Candida glabrata

mBio
Recent epidemiological studies documented an alarming increase in the prevalence of echinocandin-resistant (ECR) Candida glabrata blood isolates. ECR isolates are known to arise from a minor subpopulation of a clonal population, termed echinocandin ...
Amir Arastehfar, Farnaz Daneshnia, Daniel J. Floyd, Nathan Elias Jeffries, Mostafa Salehi, David S. Perlin, Macit Ilkit, Cornelia Lass-Flöerl, Michael K. Mansour   +8 more
doaj   +1 more source

Tipping the balance both ways: drug resistance and virulence in Candida glabrata [PDF]

, 2017
Among existing fungal pathogens, Candida glabrata is outstanding in its capacity to rapidly develop resistance to currently used antifungal agents. Resistance to the class of azoles, which are still widely used agents, varies in proportion (from 5 to 20%)
Bolotin-Fukuhara, Monique, Sanglard, Dominique, Vale-Silva, Luis A.   +2 more
core  

Why do echinocandins fail? Identifying key predictors to improve clinical outcomes of candida bloodstream infections: a retrospective multicenter cohort study

International Journal of Infectious Diseases
Background: Echinocandins represent first-line therapy for Candida Bloodstream Infections (C-BSIs). Incidence of treatment failure (TF) remains high with unclear risk factors. Aim: to evaluate predictors of echinocandin TF for C-BSIs.
Davide Fiore Bavaro, Lucia Diella, Alessandro De Angelis, Massimo Vanoni, Alessandra Belati, Laura De Santis, Linda Bussini, Laura Montemurro, Roberto Papale, Luigi Ronga, Maria Calabrò, Erminia Casari, Monica Stufano, Lidia Dalfino, Federica Tordato, Paola Morelli, Nadia Fusilli, Gianluca Castellani, Elena Costantini, Francesco Di Gennaro, Valeria Cento, Dario Cattaneo, Salvatore Grasso, Annalisa Saracino, Sergio Carbonara, Giovanni Berna, Maurizio Cecconi, Michele Bartoletti   +27 more
doaj   +1 more source

Resistance to Echinocandins in Candida Can Be Detected by Performing the Etest Directly on Blood Culture Samples [PDF]

, 2018
María Ángeles Bordallo-Cardona, Laura Judith Marcos-Zambrano, Carlos Sánchez‐Carrillo, Emilio Bouza, Patricia Muñóz, Pilar Escribano, Jesús Guinea   +6 more
openalex   +1 more source

Comparison of In Vitro Activities of the New Triazole SCH56592 and the Echinocandins MK-0991 (L-743,872) and LY303366 against Opportunistic Filamentous and Dimorphic Fungi and Yeasts [PDF]

, 1998
Ana Espinel‐Ingroff
openalex   +1 more source

P017 Echinocandin resistance mechanism in Candida tropicalis and Candida glabrata [PDF]

, 2022
Dipti Sharma, Raees A. Paul, Jayashree Murlidharan, Sadhna Sharma, Harsimran Kaur, Anup Ghosh, Arunaloke Chakrabarti, Shivaprakash M. Rudramurthy   +7 more
openalex   +1 more source