Results 181 to 190 of about 230,272 (282)

DEPENDENCY IDENTIFICATION FOR ENGINEERING CHANGE MANAGEMENT (ECM): AN EXAMPLE OF COMPUTER-AIDED DESIGN (CAD)-BASED APPROACH

, 2015
Mahmoud Masmoudi, Patrice Leclaire, Marc Zolghadri, Mohamed Haddar   +3 more
openalex   +1 more source

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

Advanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin, Alexander Chen, Quincy P. Lyons, Michael B. Nguyen, Maria L. Karkanitsa, Justin Yu, Van K. Ninh, Emily Gardner, Elyse G. Wong, Sriya N. Paleti, Julian Cheng, Benjamin D. Bridgelal, Kate E. Reimold, Selena Cao, Connor Uhre, Colin G. Luo, Zhenxing Fu, Kevin R. King, Karen L. Christman   +18 more
wiley   +1 more source

Thrombospondin 1 and 2 regulate mesenchymal progenitor cell fate and matrix organization. [PDF]

Bone Res
Hunter MK, Korlakunta S, Vishlaghi N, Mittal M, Cragg K, Juan C, Pagani CA, Sun Y, Lammlin L, Kessell K, Feist D, Choi JH, Hsieh ML, Saikia J, Duvall CL, Kang H, Alford AI, Hankenson KD, Tower RJ, Maerz T, Levi B.   +20 more
europepmc   +1 more source

lncRNA MIAT increases cell viability, migration, EMT and ECM production in age‑related cataracts by regulating the miR‑181a/CTGF/ERK signaling pathway

, 2020
Jiaojiao Ling, Ke Tan, Lu Lu, Fang Yang, Lan Luan   +4 more
openalex   +2 more sources

Geometrical Designs in Volumetric Bioprinting to Study Cellular Behaviors in Engineered Constructs

Advanced Healthcare Materials, EarlyView.
Curvature and spatial confinement guide cell behavior in volumetrically printed 3D constructs. Endothelial cells align and spread along specific geometries, while metastatic osteosarcoma cells proliferate independently of structural cues. Label‐free holographic microscopy captures real‐time, long‐term cell–material interactions, highlighting Gel‐PEG's ...
Julia Simińska‐Stanny, Pierre Tournier, Armin Shavandi, Shukry J Habib   +3 more
wiley   +1 more source

The Functional Epididymal Amyloid Cystatin-Related Epididymal Spermatogenic (CRES) is a Component of the Mammalian Brain Extracellular Matrix. [PDF]

J Neurosci Res
Gomez A, Tran UT, Grozdanov PN, Cornwall GA.   +3 more
europepmc   +1 more source

The emerging role of ECM crosslinking in T cell mobility as a hallmark of immunosenescence in humans

, 2016
Jean-François Moreau, Thomas Pradeu, Andrea Grignolio, Christine Nardini, Filippo Castiglione, Paolo Tieri, Miriam Capri, Stefano Salvioli, Jean‐Luc Taupin, Paolo Garagnani, Claudio Franceschi   +10 more
openalex   +2 more sources

A 3D Bioprinted Spheroid‐Laden dECM‐Enriched Osteosarcoma Model for Enhanced Drug Testing and Therapeutic Discovery

Advanced Healthcare Materials, EarlyView.
A 3D biomimetic OS model was developed by bioprinting an OS‐cell‐derived dECM‐enriched bioink with OS spheroids incorporated. The model showed upregulation of known OS prognostic markers and increased resistance to doxorubicin, compared to 2D cultures and scaffold‐free spheroids, making this a more clinically relevant platform for drug discovery ...
Margarida F. Domingues, Maria Catarina Carreira, Mafalda S. Santos, Daniela Pacheco, Frederico Castelo Ferreira, Paola Sanjuan‐Alberte, João Carlos Silva   +6 more
wiley   +1 more source

Molecular Mechanisms of Chondrocyte Hypertrophy Mediated by Physical Cues and Therapeutic Strategies in Osteoarthritis. [PDF]

Int J Mol Sci
Jin GZ.
europepmc   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source